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The Fascia Guide

Research.

Every peer-reviewed study on fascia in one place — graded for strength of evidence, summarised in plain language for clinicians, researchers, and curious patients.

We grade studies from A to 1A+++ using the Fascia Research Database rubric — 1A+++ is the strongest.

2,804
studies
602
top-graded
2,783
with plain-language summary
TopicAllfascia233extracellular matrix51hyaluronan46inflammation40Connective tissue39mechanotransduction36collagen32Vitamin C31Manual Therapy30acupuncture24
GradeAll1A+++41A++21A+42A++++1A+++317A++236A+84A435
YearAll yearsSince 2020Since 2015Since 2010With summary
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Showing 1–5 of 5 studiescollagenASince 2010
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  1. A
    2019

    Oral Collagen Supplementation: A Systematic Review of Dermatological Applications

    Franchesca D Choi, Calvin T Sung, Margit L W Juhasz, Natasha Atanaskova Mesinkovsk

    This systematic review examined eleven clinical trials investigating the impact of oral collagen supplements on skin health. The findings suggest that collagen hydrolysates and peptides may improve skin elasticity, hydr…

    wound healingcollagenskin aging
  2. A
    2013

    Molecular assembly and mechanical properties of the extracellular matrix: A fibrous protein perspective

    Lisa D Muiznieks, Fred W Keeley

    This review article examines the extracellular matrix (ECM), the dynamic network of molecules surrounding our cells. The authors focus on fibrous proteins like collagen and elastin, which form the structural backbone of…

    fasciaextracellular matrixcollageneastinself-assembly
  3. A
    2011

    Exercise training reduces fibrosis and matrix metalloproteinase dysregulation in the aging rat heart

    Hyo-Bum Kwak, Jong-hee Kim, Kumar Joshi, Alvin Yeh, Daniel A Martinez, John M Lawler

    In this animal study, researchers investigated how exercise affects age-related fibrosis (scarring) in the rat heart. They found that aging was associated with an increase in collagen and a dysregulation of enzymes call…

    collagenRemodelingTIMP-1
  4. A
    2011

    The extracellular matrix: an active or passive player in fibrosis?

    T N Wight, S Potter-Perigo

    Fibrosis, the excessive buildup of scar tissue, can be understood as a wound healing process that has gone awry. Normally, specialized cells called myofibroblasts help repair tissue and then disappear, but in fibrosis,…

    fasciaprovisional extracellular matrixmyofibroblatcollagenhyaluronan proteoglycans
  5. A
    2010

    3D reconstruction of the crural and thoracolumbar fasciae

    L Benetazzo, A Bizzego, R De Caro, G Frigo, D Guidolin, Carla Stecco

    Researchers created detailed 3D computer models to visualize the structure of the crural fascia in the lower leg and the superficial layer of the thoracolumbar fascia in the lower back. They found the crural fascia is c…

    Connective tissuecollagenThoracolumbar fasciacrural fascia3D models