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The Fascia Guide

Research.

Every peer-reviewed study on fascia in one place — graded for strength of evidence, summarised in plain language for clinicians, researchers, and curious patients.

We grade studies from A to 1A+++ using the Fascia Research Database rubric — 1A+++ is the strongest.

2,804
studies
602
top-graded
2,783
with plain-language summary
TopicAllfascia233extracellular matrix51hyaluronan46inflammation40Connective tissue39mechanotransduction36collagen32Vitamin C31Manual Therapy30acupuncture24
GradeAll1A+++41A++21A+42A++++1A+++317A++236A+84A435
YearAll yearsSince 2020Since 2015Since 2010With summary
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  1. A+
    2019

    Collagen changes in pelvic support tissues in women with pelvic organ prolapse

    Runqi Gong, Zhijun Xia

    This narrative review summarizes research on how changes in collagen are linked to pelvic organ prolapse in women. Collagen is a critical component of the pelvic floor, providing essential supportive functions. Studies…

    extracellular matrixcollagenBiomechanicsPelvic organ prolapseSignaling pathways
  2. A+
    2015

    Osmotic pressure induced tensile forces in tendon collagen

    Admir Masic, Luca Bertinetti, Roman Schuetz, Shu-Wei Chang, Till Hartmut Metzger, Markus J Buehler, Peter Fratzl

    Researchers investigated the role of water in tendon collagen using a combination of experiments and computer modeling. They found that water is a crucial part of the collagen molecule's structure. When water is removed…

    collagenOsmotic pressurewater
  3. A+
    2012

    The effect of menopause on the skin and other connective tissues

    J Calleja-Agius, M Brincat

    This narrative review examines how menopause and the resulting decline in estrogen affect the body's connective tissues, particularly the skin. Research suggests that skin collagen levels drop significantly following me…

    collagenageingskin tissuemenopauseoestrogen