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Research.

Every peer-reviewed study on fascia in one place — graded for strength of evidence, summarised in plain language for clinicians, researchers, and curious patients.

We grade studies from A to 1A+++ using the Fascia Research Database rubric — 1A+++ is the strongest.

2,804
studies
602
top-graded
2,783
with plain-language summary
Showing 1–21 of 21 studiesfasciaA++
Clear
A++2023

Change in gliding properties of the iliotibial tract in hypermobile Ehlers–Danlos Syndrome

Tina J Wang, Antonio Stecco, Robert Schleip, Carla Stecco, Carmelo Pirri

This study used ultrasonography to examine the gliding properties of the iliotibial tract (ITT) in individuals with hypermobile Ehlers-Danlos Syndrome (hEDS). Researchers found that the shear strain, which represents ho…

fasciashear strainultrasonography
A++2020

Ultrasound imaging of a scar on the knee: Sonopalpation for fascia and subcutaneous tissues

Carmelo Pirri, Antonio Stecco, Caterina Fede, Raffaele De Caro, Carla Stecco, Levent Özçakar

Persistent pain from surgical or trauma-related scars is a common and sometimes debilitating problem. In this article, the authors describe the use of ultrasound imaging to provide an objective diagnosis for debilitatin…

fasciapainscar
A++2020

Fascia and soft tissues innervation in the human hip and their possible role in post-surgical pain

Caterina Fede, Andrea Porzionato, Lucia Petrelli, Chenglei Fan, Carmelo Pirri, Carlo Biz, Raffaele De Caro, Carla Stecco

Researchers investigated the nerve supply to various soft tissues in the human hip to better understand persistent pain after hip replacement surgery. Analyzing tissue samples from patients and cadavers, they measured t…

fasciapaininnervation
A++2019

The architecture and spatial organization of the living human body as revealed by intratissular endoscopy - An osteopathic perspective

Colin Armstrong

This review article discusses research by Dr. Jean-Claude Guimberteau, who used endoscopy to visualize the internal architecture of the living body. His work reveals a continuous, body-wide multifibrillar network that t…

fasciaextracellular matrixosteopathy
A++2018

Bone is fascia

Stephen Levin

This entry, based on its title alone, proposes a conceptual link between bone and fascia. Without an abstract or full text, the specific arguments made by the author remain unclear. The title 'Bone is fascia' suggests a…

fascia
A++2017

Biological effects of direct and indirect manipulation of the fascial system. Narrative review

Giovanni Parravicini, Andrea Bergna

This narrative review explores the biological effects of manual fascial therapies. While osteopathic manipulative treatment (OMT) is clinically effective, its underlying mechanisms are not fully understood. The authors…

fasciaMyofascial releaseManual Therapy
A++2016

Ultra-weak photon emission in healthy subjects and patients with type 2 diabetes: evidence for a non-invasive diagnostic tool

Meina Yang, Wenyu Ding, Yanli Liu, Hua Fan, Rajendra P Bajpai, Jialei Fu, Jingxiang Pang, Xiaolei Zhao, Jinxiang Han

All living organisms emit extremely faint light, known as ultra-weak photon emission (UPE). This study investigated whether these light emissions differ between healthy individuals and people with type 2 diabetes. Resea…

fasciaphoton emissionbiological systems
A++2015

The Effects of Vibration and Muscle Fatigue on Trunk Sensorimotor Control in Low Back Pain Patients

Jean-Alexandre Boucher, Jacques Abboud, François Nougarou, Martin C Normand, Martin Descarreaux

This study compared trunk muscle control between people with chronic low back pain (cLBP) and healthy individuals. Researchers found that the cLBP group was less accurate at reproducing a specific amount of force with t…

fascialow back painmuscle fatigue
A++2014

Spatiotemporal Imaging of Glutamate-Induced Biophotonic Activities and Transmission in Neural Circuits

Rendong Tang, Jiapei Dai

This study on mouse brain tissue investigated biophotons, which are ultra-weak light emissions from biological systems. Researchers found that applying the neurotransmitter glutamate caused a significant and long-lastin…

fasciabiophotonsultraweak photons
A++2014

New perspective in cell communication: Potential role of ultra-weak photon emission

Ankush Prasad, Claudio Rossi, Stefania Lamponi, Pavel Pospíšil, Alberto Foletti

This 2014 narrative review explores how cells might communicate with each other. Beyond chemical signals and direct contact, the authors discuss evidence for communication via electromagnetic radiation, specifically ult…

fasciabiophotonsUltra-weak photon emission
A++2013

Squeeze film lubrication for non-Newtonian fluids with application to manual medicine

Hans Chaudhry, Bruce Bukiet, Max Roman, Antonio Stecco, Thomas Findley

Researchers used a mathematical model to investigate how manual therapy affects the fluid in and around fascia. The model focused on hyaluronic acid (HA), a natural lubricant in connective tissue. The results suggest th…

fasciaHyaluronic acidmassage therapy
A++2013

Vibration Induced Osteogenic Commitment of Mesenchymal Stem Cells is Enhanced by Cytoskeletal Remodeling but not Fluid Shear

Gunes Uzer, Suphannee Pongkitwitoon, M Ete Chan, Stefan Judex

This laboratory study investigated how mechanical vibrations encourage stem cells to develop into bone cells. Researchers tested two potential mechanisms: the force of fluid moving across the cells (fluid shear) and cha…

fasciaBonedifferentiation
A++2013

Implementation of Matrix Rhythm Therapy and Conventional Massage in Young Females and Comparison of Their Acute Effects on Circulation

Ferruh Taspinar, Ummuhan Bas Aslan, Nuran Sabir, Ugur Cavlak

This randomized controlled trial compared the acute effects of Matrix Rhythm Therapy and conventional massage on lower leg blood circulation in young, healthy women. Fifteen participants received a single 30-minute sess…

fascia
A++2013

Mathematical Analysis of the Flow of Hyaluronic Acid Around Fascia During Manual Therapy Motions

Max Roman, Hans Chaudhry, Bruce Bukiet, Antonio Stecco,Thomas Findley

This study used a mathematical model to simulate how different manual therapy techniques affect the flow of hyaluronic acid (HA) within fascia. The researchers compared constant sliding, perpendicular vibration, and tan…

hyaluronanfasciaManual Therapy
A++2012

Lymphatic and interstitial flow in the tumour microenvironment: linking mechanobiology with immunity

Melody A Swartz, Amanda W Lund

This review explores how tumors interact with the lymphatic system to grow and spread. Increased fluid flow from a tumor to nearby lymph nodes does more than just transport cancer cells. This flow also creates mechanica…

fasciacancerstiffness
A++2011

Review of Evidence Suggesting That the Fascia Network Could Be the Anatomical Basis for Acupoints and Meridians in the Human Body

Yu Bai, Jun Wang, Jin-Peng Wu, Jing-Xing Dai, Ou Sha, David Tai Wai Yew, Lin Yuan, Qiu-Ni Liang

This narrative review explores the idea that the body's fascia network could be the physical structure behind traditional Chinese medicine's (TCM) meridians and acupoints. The authors examine anatomical, physiological,…

fasciaacupunctureacupoints
A++2010

Biophotons as neural communication signals demonstrated by in situ biophoton autography

Yan Sun, Chao Wang, Jiapei Dai

This in vitro study on rat nerve tissue explored whether biophotons—extremely weak light emitted by living cells—could act as signals in the nervous system. Researchers stimulated one end of a spinal nerve root with var…

fasciabiophotonsultraweak photons
A++2009

Imaging of Ultraweak Spontaneous Photon Emission from Human Body Displaying Diurnal Rhythm

Masaki Kobayashi, Daisuke Kikuchi, Hitoshi Okamura

The human body emits an extremely faint light, about 1000 times dimmer than what our naked eyes can detect. This phenomenon, known as ultraweak photon emission, is thought to be linked to the body's energy metabolism. U…

fasciabiophotonsultraweak photons
A++2009

Bonghan Circulatory System as an Extension of Acupuncture Meridians

Kwang-Sup Soh

This article describes the Bonghan circulatory system (BHS), a network proposed in the 1960s to correspond with classical acupuncture meridians. After a long period of being overlooked, researchers have recently develop…

fasciacanceracupuncture meridian
A++2008

Humoral phototransduction: Light transportation in the blood, and possible biological effects

F Grass, S Kasper

In this theoretical paper, researchers propose a model called 'humoral phototransduction' to explain how light might affect the body beyond the eyes. They observed that blood plasma, and particularly the protein albumin…

fasciabiophotonsultraweak photons
A++2006

Quantum Events of Biophoton Emission Associated with Complementary and Alternative Medicine Therapies: A Descriptive Pilot Study

Marius Hossu, Ronald Rupert

This descriptive pilot study investigated biophoton emission (BPE), an ultra-low level of light emitted by living organisms that may reflect overall health status. Researchers measured BPE from the neck and lower back o…

fasciaManual Therapybiophotons