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The Fascia Guide

Research.

Every peer-reviewed study on fascia in one place — graded for strength of evidence, summarised in plain language for clinicians, researchers, and curious patients.

We grade studies from A to 1A+++ using the Fascia Research Database rubric — 1A+++ is the strongest.

2,804
studies
602
top-graded
2,783
with plain-language summary
TopicAllfascia233extracellular matrix51hyaluronan46inflammation40Connective tissue39mechanotransduction36collagen32Vitamin C31Manual Therapy30acupuncture24
GradeAll1A+++41A++21A+42A++++1A+++317A++236A+84A435
YearAll yearsSince 2020Since 2015Since 2010With summary
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Showing 1–3 of 3 studiesextracellular matrixA++Since 2015
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  1. A++
    2023

    Functional organization of extracellular hyaluronan, CD44 and RHAMM

    Mary K Cowman, Eva A Turley

    In this comprehensive review, the authors explore how hyaluronan (HA) and its receptors, CD44 and RHAMM, organize the space immediately surrounding cells. In healthy tissue, these components maintain a stable environmen…

    hyaluronanCD44extracellular matrixRHAMMpericellular matrix
  2. A++
    2020

    The Structure and Role of Intramuscular Connective Tissue in Muscle Function

    Peter P Purslow

    This narrative review analyzes the microscopic structure of intramuscular connective tissue—endomysium, perimysium, and epimysium—and its role in muscle function. Rather than acting simply as a container, this connectiv…

    extracellular matrixMusclecollagenmechanotransductionperimysium
  3. A++
    2019

    The architecture and spatial organization of the living human body as revealed by intratissular endoscopy - An osteopathic perspective

    Colin Armstrong

    This review article discusses research by Dr. Jean-Claude Guimberteau, who used endoscopy to visualize the internal architecture of the living body. His work reveals a continuous, body-wide multifibrillar network that t…

    fasciaextracellular matrixosteopathyCollagen fibersFibrillar network