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The Fascia Guide

Research.

Every peer-reviewed study on fascia in one place — graded for strength of evidence, summarised in plain language for clinicians, researchers, and curious patients.

We grade studies from A to 1A+++ using the Fascia Research Database rubric — 1A+++ is the strongest.

2,804
studies
602
top-graded
2,783
with plain-language summary
TopicAllfascia233extracellular matrix51hyaluronan46inflammation40Connective tissue39mechanotransduction36collagen32Vitamin C31Manual Therapy30acupuncture24
GradeAll1A+++41A++21A+42A++++1A+++317A++236A+84A435
YearAll yearsSince 2020Since 2015Since 2010With summary
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Showing 1–2 of 2 studiesManual TherapyA++Since 2010
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  1. A++
    2017

    Biological effects of direct and indirect manipulation of the fascial system. Narrative review

    Giovanni Parravicini, Andrea Bergna

    This narrative review explores the biological effects of manual fascial therapies. While osteopathic manipulative treatment (OMT) is clinically effective, its underlying mechanisms are not fully understood. The authors…

    fasciaMyofascial releaseManual TherapyMyofascial manipulation
  2. A++
    2013

    Mathematical Analysis of the Flow of Hyaluronic Acid Around Fascia During Manual Therapy Motions

    Max Roman, Hans Chaudhry, Bruce Bukiet, Antonio Stecco,Thomas Findley

    This study used a mathematical model to simulate how different manual therapy techniques affect the flow of hyaluronic acid (HA) within fascia. The researchers compared constant sliding, perpendicular vibration, and tan…

    hyaluronanfasciaManual Therapyfluid flowvibration