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The Fascia Guide

Research.

Every peer-reviewed study on fascia in one place — graded for strength of evidence, summarised in plain language for clinicians, researchers, and curious patients.

We grade studies from A to 1A+++ using the Fascia Research Database rubric — 1A+++ is the strongest.

2,804
studies
602
top-graded
2,783
with plain-language summary
TopicAllfascia233extracellular matrix51hyaluronan46inflammation40Connective tissue39mechanotransduction36collagen32Vitamin C31Manual Therapy30acupuncture24
GradeAll1A+++41A++21A+42A++++1A+++317A++236A+84A435
YearAll yearsSince 2020Since 2015Since 2010With summary
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Showing 1–7 of 7 studiesVitamin CA+++
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  1. A+++
    2020

    Antiviral Mechanisms of Vitamin C: A Short Communication Consensus Report

    Michael J Gonzalez, Jorge R Miranda-Massari, Jose R Rodriguez, Victor Marcial-Vega, Miguel J Berdiel, Jorge Duconge, St…

    This 2020 publication is a consensus report from a large group of authors, summarizing agreed-upon points regarding vitamin C. Based on the title, the report details the various mechanisms by which vitamin C may exert a…

    Vitamin CAscorbic acidantiviral effects
  2. A+++
    2020

    Is the VITAMINS RCT indicating potential redundancy between corticosteroids and vitamin C?

    Anitra C Carr

    Known only by its title, this article appears to be a commentary or analysis of a randomized controlled trial (RCT) known as VITAMINS. The title poses a question about whether there might be a "redundancy," or overlappi…

    Vitamin Ccorticosteroidsstress respons
  3. A+++
    2020

    Overview of the possible role of vitamin C in management of COVID-19

    Anis Abobaker, Aboubaker Alzwi, Alsalheen Hamed A Alraied

    In this 2020 review, the authors examine the possible role of vitamin C in managing COVID-19. They note that the body's vitamin C levels often drop during an acute infection due to increased metabolic demands. Because v…

    Vitamin CCOVID-19SARS-CoV-2Beneficial effectsManagement
  4. A+++
    2020

    Continuous Ascorbate Infusions in the Management of Patients with Advanced Colon Cancer

    Nina Mikirova

    This study analyzed data from a previous clinical trial involving 17 patients with late-stage colon cancer. The patients received continuous intravenous infusions of vitamin C (ascorbate) over 6-8 weeks. Researchers fou…

    Vitamin CAscorbic acidcolon cancer
  5. A+++
    2019

    Vitamin C administration in the critically ill: a summary of recent meta-analyses

    Anitra C Carr

    This 2019 publication is a summary of recent meta-analyses on the topic of vitamin C administration for critically ill patients. As the full text has not yet been reviewed, a detailed summary of its findings is not avai…

    Vitamin CAscorbic acidsepsis
  6. A+++
    2018

    Evidence is stronger than you think: a meta-analysis of vitamin C use in patients with sepsis

    Jing Li

    This commentary presents a meta-analysis of research on using vitamin C to treat sepsis. It builds upon two previous reviews by pooling their data for a combined statistical analysis. The aggregated results indicated a…

    meta-analysisVitamin CAscorbic acidsepsisSevere sepsis
  7. A+++
    2013

    Vitamin C Is an Essential Factor on the Anti-viral Immune Responses through the Production of Interferon-α/β at the Initial Stage of Influenza A Virus (H3N2) Infection

    Yejin Kim, Hyemin Kim, Seyeon Bae, Jiwon Choi, Sun Young Lim, Naeun Lee, Joo Myung Kong, Young-il Hwang, Jae Seung Kang…

    This animal study investigated how vitamin C affects the immune response to influenza A virus (H3N2). Researchers used mice that, like humans, cannot synthesize their own vitamin C. When these mice were made vitamin C-d…

    immune responseVitamin Cantiviralinfluenza Ainterferon alfa/beta