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The Fascia Guide

Research.

Every peer-reviewed study on fascia in one place — graded for strength of evidence, summarised in plain language for clinicians, researchers, and curious patients.

We grade studies from A to 1A+++ using the Fascia Research Database rubric — 1A+++ is the strongest.

2,804
studies
602
top-graded
2,783
with plain-language summary
TopicAllfascia233extracellular matrix51hyaluronan46inflammation40Connective tissue39mechanotransduction36collagen32Vitamin C31Manual Therapy30acupuncture24
GradeAll1A+++41A++21A+42A++++1A+++317A++236A+84A435
YearAll yearsSince 2020Since 2015Since 2010With summary
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Showing 1–2 of 2 studieshyaluronanA+++With summary
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  1. A+++
    2022

    Hyaluronan homeostasis and its role in pain and muscle stiffness

    Adam Amir, Soo Kim, Antonio Stecco, Michael P Jankowski, Preeti Raghavan

    This narrative review explores the role of hyaluronan (HA) in the musculoskeletal system. HA is a key component of the extracellular matrix in muscles and fascia, where it normally functions as a lubricant and shock abs…

    hyaluronanpainmuscle stiffness
  2. A+++
    2016

    Fascial Manipulation® for chronic aspecific low back pain: a single blinded randomized controlledtrial.

    Mirco Branchini, Francesca Lopopolo, Ernesto Andreoli, Ivano Loreti, Aurélie M Marchand, Antonio Stecco

    This randomized controlled trial compared Fascial Manipulation® combined with standard physiotherapy to physiotherapy alone for patients with chronic non-specific low back pain. The group receiving Fascial Manipulation®…

    hyaluronanBack PainFascial manipulation