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Research.

Every peer-reviewed study on fascia in one place — graded for strength of evidence, summarised in plain language for clinicians, researchers, and curious patients.

We grade studies from A to 1A+++ using the Fascia Research Database rubric — 1A+++ is the strongest.

2,804
studies
602
top-graded
2,783
with plain-language summary
Showing 1–18 of 18 studiesfascia1A+
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1A+2019

The Other Side of the Fascia: Visceral Fascia, Part 2

Bruno Bordoni, Marta Simonelli, Bruno Morabito

This editorial, part two of a series, argues for including certain internal organs (viscera) within the definition of fascia. From an osteopathic perspective, the authors suggest that understanding these organs as fasci…

fasciaMyofascialOsteopathic
1A+2019

The Other Side of the Fascia: The SmoothMuscle Part 1

Bruno Bordoni, Marta Simonelli, Bruno Morabito

This theoretical article challenges the standard definition of fascia. Traditionally, fascia is considered connective tissue originating from two embryonic layers, the mesoderm and ectoderm. The authors propose expandin…

fasciaMyofascialOsteopathic
1A+2019

The fascial breath

Bruno Bordoni, Marta Simonelli, Bruno Morabito

This narrative review proposes a new way of understanding the diaphragm muscle, moving beyond a purely mechanical view. The authors argue that the diaphragm is not just covered by fascia but is fundamentally a fascial t…

fasciaMyofascialOsteopathic
1A+2019

Role of fasciae in nonspecific low back pain

G Casato, Carla Stecco, R Busin

Research increasingly links the thoracolumbar fascia to non-specific low back pain. This small case study explored the idea that pain could originate elsewhere in the body's continuous fascial network. Five patients wit…

fascianonspecific low back painlimb myofascial manipulation
1A+2019

The Awareness of the Fascial System

Bruno Bordoni, Marta Simonelli

In this theoretical article, the authors propose a new way of looking at the fascial system, drawing on concepts from quantum physics. They suggest that fascial cells can sense, remember, and even anticipate mechanical…

fasciafascial systemMyofascial
1A+2019

Sensitivity of the fasciae to sex hormone levels: Modulation of collagen-I, collagen-III and fibrillin production

Caterina Fede, Carmelo Pirri, Chenglei Fan, Giovanna Albertin, Andrea Porzionato, Veronica Macchi, Raffaele De Caro, Ca…

Women experience myofascial pain more often than men, and evidence suggests fascia can be influenced by sex hormones. In this lab study, researchers examined how cells from human fascia lata responded to various levels…

fasciacollagen Icollagen III
1A+2019

Bone Tissue is an Integral Part of the Fascial System

Bruno Bordoni, Maria Marcella Lagana

This review article proposes that bone tissue should be considered an integral part of the fascial system, a departure from the current definition. The authors support this by highlighting the shared embryological origi…

fasciaBonefascial system
1A+2018

The Fasciacytes- A New Cell Devoted To Fascial Gliding Regulation

Carla Stecco, Caterina Fede, Veronica Macchi, Andrea Porzionato, Lucia Petrelli, Carlo Biz, Robert Stern, Raffaele De C…

Researchers have identified a new type of cell within fascia, which they have named "fasciacytes." This study presents evidence that these specialized cells are responsible for producing hyaluronan, a key component of t…

hyaluronanfasciafasciacytes
1A+2018

Effect of Stretching on Thoracolumbar Fascia Injury and Movement Restriction in a Porcine Model

H M Langevin, J Bishop, R Maple, G J Badger, J R Fox

In this animal study on pigs, researchers investigated the effect of stretching on the thoracolumbar fascia after injury and movement restriction. An injury combined with restricted movement led to reduced fascial mobil…

fasciaConnective tissueStretching
1A+2017

Emotions in Motion: Myofascial Interoception

B Bordoni, F Marelli

In this perspective piece, the authors argue that the myofascial system is closely linked to our emotional state. They suggest that manual treatment not only affects the body physically but also activates the interocept…

fasciaManual TherapyMyofascial
1A+2015

Fascia and Primo Vascular System

Chun Yang, Yi-kuan Du, Jian-bin Wu, JunWang, Ping Luan, Qin-lao Yang, Lin Yuan

In this review article, the authors explore the idea that the body's network of fascia may be the physical structure corresponding to acupuncture meridians in Traditional Chinese Medicine (TCM). They also discuss the pr…

fasciamechanotransductionprimo vascular system
1A+2014

Peripheral Mechanisms Contributing to Spasticity and Implications for Treatment

Antonio Stecco, Carla Stecco, P Raghavan

This narrative review explores how changes in connective tissue might contribute to spasticity following a central nervous system injury. The authors suggest that the initial injury can alter the turnover of hyaluronic…

fasciaConnective tissueStroke
1A+2014

Painful Connections: Densification Versus Fibrosis of Fascia

P G Pavan, Antonio Stecco, R Stern, Carla Stecco

In this review article, the authors describe two types of fascial changes that can cause pain: densification and fibrosis. Densification is described as a reversible alteration in the viscosity of the loose connective t…

hyaluronanfasciafibrosis
1A+2014

The Medium of Haptic Perception: A Tensegrity Hypothesis

Michael T Turvey, Sérgio T Fonseca

In this theoretical paper, the authors propose a new hypothesis for how our sense of touch, or haptic perception, works. Unlike other senses that have a clear medium (like air for sound), the haptic system lacks one. Th…

fasciaConnective tissuecytoskeleton
1A+2013

Fascial Components of the Myofascial Pain Syndrome

Antonio Stecco, M Gesi, Carla Stecco, R Stern

Myofascial pain syndrome (MPS) involves muscle pain and other symptoms linked to trigger points, but the role of fascia is often overlooked. This review summarizes recent research into the biology of fascia to better un…

fasciaHyaluronic aciddensification
1A+2012

Stretching of the Back Improves Gait, Mechanical Sensitivity and Connective Tissue Inflammation in a Rodent Model

S M Corey, M A Vizzard, N A Bouffard, G J Badger, H M Langevin

In this rodent study, researchers investigated how stretching affects inflammation in the connective tissue of the low back. They first induced local inflammation, which resulted in altered gait, increased mechanical se…

fasciaConnective tissueStretching
1A+2008

Tissue Stretch Decreases Soluble TGF-β1 and Type-1 Procollagen in Mouse Subcutaneous Connective Tissue: Evidence From Ex Vivo and In Vivo Models

N A Bouffard, K R Cutroneo, G J Badger, S L White, T R Buttolph, H P Ehrlich, D Stevens-Tuttle, H M Langevin

This study on mice investigated how brief, static stretching affects connective tissue healing after an injury. Researchers used two models: tissue samples cultured outside the body (ex vivo) and live mice with minor su…

fasciaConnective tissueStretching
1A+2003

The Common Compensatory Pattern: Its Origin and Relationship to the Postural Model

Ross E Pope

As only the title of this paper is available, we cannot summarize its contents in detail. The title suggests the article explores a concept known as the 'Common Compensatory Pattern'. The author likely discusses the ori…

fasciaCompensatory patternposture