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Research.

Every peer-reviewed study on fascia in one place — graded for strength of evidence, summarised in plain language for clinicians, researchers, and curious patients.

We grade studies from A to 1A+++ using the Fascia Research Database rubric — 1A+++ is the strongest.

2,804
studies
602
top-graded
2,783
with plain-language summary
Showing 1–7 of 7 studiesConnective tissue1A+
Clear
1A+2019

Fascia Is Able to Actively Contract and May Thereby Influence Musculoskeletal Dynamics: A Histochemical and Mechanographic Investigation

Robert Schleip, G Gabbiani, Jan Wilke, I Naylor, B Hinz, A Zorn, Heike Jäger, R Breul, S Schreiner, Werner Klingler

This study investigated whether fascia can actively contract, challenging the traditional view of it as a passive tissue. Researchers examined human and rat fascial samples for the presence of contractile cells called m…

Connective tissuestiffnessmyofibroblasts
1A+2018

Effect of Stretching on Thoracolumbar Fascia Injury and Movement Restriction in a Porcine Model

H M Langevin, J Bishop, R Maple, G J Badger, J R Fox

In this animal study on pigs, researchers investigated the effect of stretching on the thoracolumbar fascia after injury and movement restriction. An injury combined with restricted movement led to reduced fascial mobil…

fasciaConnective tissueStretching
1A+2014

The Medium of Haptic Perception: A Tensegrity Hypothesis

Michael T Turvey, Sérgio T Fonseca

In this theoretical paper, the authors propose a new hypothesis for how our sense of touch, or haptic perception, works. Unlike other senses that have a clear medium (like air for sound), the haptic system lacks one. Th…

fasciaConnective tissuecytoskeleton
1A+2014

Painful Connections: Densification Versus Fibrosis of Fascia

P G Pavan, Antonio Stecco, R Stern, Carla Stecco

In this review article, the authors describe two types of fascial changes that can cause pain: densification and fibrosis. Densification is described as a reversible alteration in the viscosity of the loose connective t…

hyaluronanfasciafibrosis
1A+2014

Peripheral Mechanisms Contributing to Spasticity and Implications for Treatment

Antonio Stecco, Carla Stecco, P Raghavan

This narrative review explores how changes in connective tissue might contribute to spasticity following a central nervous system injury. The authors suggest that the initial injury can alter the turnover of hyaluronic…

fasciaConnective tissueStroke
1A+2012

Stretching of the Back Improves Gait, Mechanical Sensitivity and Connective Tissue Inflammation in a Rodent Model

S M Corey, M A Vizzard, N A Bouffard, G J Badger, H M Langevin

In this rodent study, researchers investigated how stretching affects inflammation in the connective tissue of the low back. They first induced local inflammation, which resulted in altered gait, increased mechanical se…

fasciaConnective tissueStretching
1A+2008

Tissue Stretch Decreases Soluble TGF-β1 and Type-1 Procollagen in Mouse Subcutaneous Connective Tissue: Evidence From Ex Vivo and In Vivo Models

N A Bouffard, K R Cutroneo, G J Badger, S L White, T R Buttolph, H P Ehrlich, D Stevens-Tuttle, H M Langevin

This study on mice investigated how brief, static stretching affects connective tissue healing after an injury. Researchers used two models: tissue samples cultured outside the body (ex vivo) and live mice with minor su…

fasciaConnective tissueStretching