Research.
Every peer-reviewed study on fascia in one place — graded for strength of evidence, summarised in plain language for clinicians, researchers, and curious readers.
We grade studies from A to 1A+++ using the Fascia Research Database rubric — 1A+++ is the strongest.
Researchers behind the studiesClinical consequences of anal sphincter rupture during vaginal delivery
This study investigated the incidence and consequences of anal sphincter tears during childbirth. Researchers followed 51 women with a diagnosed tear and 31 women without one for six months after delivery. They found th…
Effects of continuous and Intermittent forces on human fibroblasts in vitro
This in vitro study investigated how human connective tissue cells (fibroblasts) respond to different types of mechanical force. Researchers grew fibroblasts on flexible membranes and subjected them to either continuous…
Selective regulation of myofiber differentiation by energy status during postnatal development
In this animal study, researchers investigated how energy intake and environmental temperature affect muscle development in young pigs. The pigs were divided into groups that received either a high or low energy intake…
Triggerband technique
The Triggerband Technique is a manual therapy approach for treating musculoskeletal pain and dysfunction. It is based on the idea that distorted or injured fascial bands are the cause of many types of physical discomfor…
Glutathione-Ascorbic Acid Antioxidant System in Animals
This 1994 publication by Alton Meister discusses the biochemical interaction between glutathione and ascorbic acid (Vitamin C) within animal antioxidant systems. As the source material is limited to the title, the summa…
Anal-sphincter disruption during vaginal delivery
Researchers investigated how often hidden (occult) damage to the anal sphincter occurs during vaginal childbirth and how it affects bowel control. They studied over 200 women before and after delivery using ultrasound a…
Angiogenic oligosaccharides of hyaluronan enhance the production of collagens by endothelial cells
This study investigated how small fragments of hyaluronan (HA) affect collagen production during the formation of new blood vessels, a process called angiogenesis. Researchers observed that applying these HA fragments t…
Immunological evidence for the accumulation of lipoprotein(a) in the atherosclerotic lesion of the hypoascorbemic guinea pig
This animal study investigated the link between vitamin C, a specific cholesterol particle called Lipoprotein(a) or Lp(a), and atherosclerosis. Researchers found that guinea pigs, which like humans cannot produce their…
Endothelial Growth Factors and Extracellular Matrix Regulate Dna Synthesis Through Modulation of Cell and Nuclear Expansion
This study investigated how the extracellular matrix (ECM) and growth factors work together to regulate the growth of capillary endothelial cells, which line blood vessels. Researchers found that these cells needed both…
Structure and Properties of Ground Substances
This 1984 review outlines the structure of the body's 'ground substance,' the matrix found both within and between our cells. The author describes how this substance is composed of different biopolymers in the extracell…
THE INFLUENCE OF MECHANICAL FORCES ON THE GLYCOSAMINOGLYCAN CONTENT OF THE RABBIT FLEXOR DIGITORUM PROFUNDUS TENDON
In this animal study on rabbits, researchers surgically altered the mechanical forces on a deep finger flexor tendon to observe how the tissue adapted. They analyzed how the content of glycosaminoglycans (GAGs)—molecule…
Ascorbic acid status in idiopathic hemochromatosis
This study investigated Vitamin C (ascorbic acid) levels in patients with idiopathic hemochromatosis, a condition characterized by excessive iron accumulation. The results showed that untreated patients had significantl…