Research.
Every peer-reviewed study on fascia in one place — graded for strength of evidence, summarised in plain language for clinicians, researchers, and curious readers.
We grade studies from A to 1A+++ using the Fascia Research Database rubric — 1A+++ is the strongest.
Researchers behind the studiesMyofascial Force Transmission via Extramuscular Pathways Occurs between Antagonistic Muscles
In this experimental study, researchers investigated whether opposing (antagonistic) muscles act independently or influence each other through their fascial connections. By lengthening a lower leg muscle (extensor digit…
Tensegrity-Based Mechanosensing from Macro to Micro
This review article, based on a lecture, explores how cells convert mechanical signals into biochemical responses. The author proposes that the body uses "tensegrity" (tensional integrity) principles, where interconnect…
Stability, continence and breathing: The role of fascia following pregnancy and delivery
Many women experience pelvic girdle pain, incontinence, or breathing issues after pregnancy and delivery. This paper explores the role of the trunk's muscles and fascia in stability, continence, and respiration. The aut…
Expression of the endocannabinoid system in fibroblasts and myofascial tissues
This narrative review investigates the endocannabinoid (eCB) system, a network in the body similar to the endorphin system that helps regulate pain and inflammation. Using a bioinformatics approach to analyze existing d…
Humoral phototransduction: Light transportation in the blood, and possible biological effects
In this theoretical paper, researchers propose a model called 'humoral phototransduction' to explain how light might affect the body beyond the eyes. They observed that blood plasma, and particularly the protein albumin…
The inflammatory response to cell death
This 2008 review article explores how the body responds when cells die from injury rather than infection. Such cell death triggers an inflammatory response that is essential for host defense and tissue repair. However,…
Mechanotransduction – a field pulling together?
In this 2008 review article, the author discusses mechanotransduction, the process by which cells convert mechanical forces into biochemical signals. Cells are constantly subjected to forces, both from external pressure…
Dorsal horn neurons having input from low back structures in rats
In this animal study, researchers in rats investigated how spinal cord nerve cells (dorsal horn neurons) process signals from the low back. They found that these neurons often receive input from several different tissue…
Magnetic Resonance Imaging of Adhesive Capsulitis: Correlation with Clinical Staging
This study investigated whether standard magnetic resonance imaging (MRI) can be used to diagnose and stage adhesive capsulitis (frozen shoulder). Researchers retrospectively reviewed MRI scans from 46 patients with an…
Ascorbate in pharmacologic concentrations selectively generates ascorbate radical and hydrogen peroxide in extracellular fluid in vivo
High-dose intravenous Vitamin C (ascorbate) can selectively kill some cancer cells without harming normal cells. Researchers have proposed this is because ascorbate acts as a prodrug, creating hydrogen peroxide and othe…
A suspensory system for the sacrum in pelvic mechanics: Biotensegrity
This 2007 publication by Stephen Levin, available only by title, appears to describe a model for understanding the mechanics of the pelvis. The title suggests a 'suspensory system' for the sacrum, framing its function w…
Cytokines, Inflammation and Pain
This review chapter describes the role of cytokines—small proteins that cells use for communication—in inflammation and pain. The authors explain that there are both pro-inflammatory and anti-inflammatory types of cytok…