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The Fascia Guide
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Research.

Every peer-reviewed study on fascia in one place — graded for strength of evidence, summarised in plain language for clinicians, researchers, and curious readers.

We grade studies from A to 1A+++ using the Fascia Research Database rubric — 1A+++ is the strongest.

Researchers behind the studies
2,806
studies
602
top-graded
2,783
with plain-language summary
TopicAllfascia233extracellular matrix51hyaluronan46inflammation40Connective tissue39mechanotransduction36collagen32Vitamin C31Manual Therapy30acupuncture24
GradeAll1A+++41A++21A+42A++++1A+++317A++236A+84A435
YearAll yearsSince 2020Since 2015Since 2010With summary
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Showing 949–954 of 954 studies · page 80/80Since 2010With summary
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  1. A
    2010

    The role and mechanical behavior of the connective tissue in tendon sliding

    J-C Guimberteau, J-P Delage, J Wong

    Based on 215 in-vivo dissections, this study challenges the traditional understanding of how tendons slide. The authors propose that tendon movement is not simple gliding, but rather occurs within a complex, adaptable c…

    Tendon; Carpal sheath; Sliding system; Tendon vascularization; Finger flexor reconstruction; Collagenic fibrillar framework; Microvacuole
  2. B
    2010

    Detail microscopic analysis of deep fascia of lower limb and its surgical implication

    Visweswar Bhattacharya, Partha Sarathi Barooah, Tapas Chandra Nag, Gaurab Ranjan Chaudhuri,, Siddhartha Bhattacharya

    This study investigated the microscopic structure of the deep fascia in the lower limb, a tissue previously thought to be relatively simple and avascular. Researchers analyzed 50 tissue specimens using light, confocal,…

    Confocal microscopydeep fasciaelectron microscopyflapmicroscopic anatomy
  3. A+
    2010

    Tendon and ligament fibrillar crimps give rise to left-handed helices of collagen fibrils in both planar and helical crimps

    Marco Franchi, Vittoria Ottani, Rita Stagni, Alessandro Ruggeri

    Tendons and ligaments have a wavy structure known as a "crimp," which straightens out as the tissue is stretched. This study on rat tissue used various microscopy techniques to examine the 3D shape of the individual col…

    collagen handedness; fibrillar crimp; helical crimps; ligament; planar crimps; tendon
  4. A
    2010

    How much time is required to modify a fascial fibrosis?

    Ercole Borgini, Antonio Stecco, Julie Ann Day, Carla Stecco

    This study investigated how long it takes for manual therapy to alter a palpable sensation of fascial "fibrosis" and reduce discomfort. Researchers worked with 40 people experiencing low back pain, applying the Fascial…

    fasciaConnective tissueManual Therapylow back painManipulation
  5. A+
    2010

    The straight line hypothesis elaborated: Case reference obesity, an argument for acidosis, oxidative stress, and disease conglomeration

    Shoma Berkemeyer

    This review article brings together existing research to explain how obesity may be linked to oxidative stress. The author proposes that a proton imbalance, or acidosis, could be a key mechanism. This imbalance may inhi…

    Oxidative stressobesityacidosisproton imbalance
  6. A
    2010

    Transcapillary exchange: role and importance of the interstitial fluid pressure and the extracellular matrix

    Rolf K Reed, Kristofer Rubin

    This narrative review discusses how the extracellular matrix (ECM) and the pressure of its fluid (interstitial fluid pressure, or Pif) regulate fluid exchange with capillaries. Conventionally, this pressure is seen as a…

    inflammationConnective tissueglycosaminoglycansbeta-Integrin receptors