Research.
Every peer-reviewed study on fascia in one place — graded for strength of evidence, summarised in plain language for clinicians, researchers, and curious readers.
We grade studies from A to 1A+++ using the Fascia Research Database rubric — 1A+++ is the strongest.
Researchers behind the studies- A2011
Hyaluronan as an Immune Regulator in Human Diseases
Paul W Noble, Jiurong Liang, Dianhua JiangThis 2011 narrative review explores the role of hyaluronan (HA) in the immune system. While intact HA is a normal part of the extracellular matrix, fragments of HA produced during tissue injury can act as signals. These…
hyaluronanfascia - A+2011
Why does chronic inflammation persist: An unexpected role for fibroblasts
C D BuckleyThis 2011 review explores why chronic inflammation persists. Traditionally, research has focused on immune cells, but this text highlights the crucial role that stromal cells, particularly fibroblasts, play in sustainin…
inflammationfasciafibroblast - B2011
Fascia Research from a Clinician/Scientist’s Perspective
Thomas W FindleyIn this perspective piece, a clinician-scientist summarizes exciting areas in fascia research. The article describes the fascial network as a body-wide system that connects individual cells and shares loads with muscles…
fasciaTensegritycollagenfibroblastconference - A2011
Dynamic fascial release and the role of mechanical/vibrational assist devices in manual therapies
Zachary ComeauxThis review article explores the use of mechanical vibration devices in manual therapy. The author examines several such tools, including percussion vibrators, vibrational platforms, and deep tissue oscillation. The art…
fasciaConnective tissuevibrationpercussion vibrationtonic vibratory reflex - C2011
Fasciae anatomy
Carla Stecco, Fabrice DuparcThis entry represents a 2011 publication titled "Fasciae anatomy" by Carla Stecco and Fabrice Duparc. As only the title is available, a detailed summary of its contents, such as its specific focus on fascial layers or c…
fasciaAnatomyfasciae - 1A+++2011
Hyaluronan within fascia in the etiology of myofascial pain
Carla Stecco, R Stern, A Porzionato, V Macchi, S Masiero, Antonio Stecco, R De CaroIn this cadaver and ultrasound study, researchers examined the composition of deep fascia. They identified layers of hyaluronan (HA), a lubricating substance, between the fascia and muscle, as well as between the fascia…
fasciaHyaluronic acidSliding systemLoose connective tissueFasciacyte - A+2011
Change in knee osteoarthritis cartilage detected by delayed gadolinium enhanced magnetic resonance imaging following treatment with collagen hydrolysate: a pilot randomized controlled trial
T E McAlindon, M Nuite, N Krishnan, R Ruthazer, L L Price, D Burstein, J Grif!th, K FlechsenharThis pilot randomized controlled trial investigated if collagen hydrolysate supplements could affect knee cartilage in people with mild osteoarthritis. Using a specialized MRI technique (dGEMRIC), researchers tracked ch…
MRIosteoarthritisMagnetic resonance imagingCartilageDelayed gadolinium enhanced - 1A+2011
Reduced thoracolumbar fascia shear strain in human chronic low back pain
Helene M Langevin, J R Fox, C Koptiuch, G J Badger, A C Greenan-Naumann, N A Bouffard, E E Konofagou, W-N Lee, J J Tria…Researchers used ultrasound to investigate the movement between layers of the thoracolumbar fascia, a large sheet of connective tissue in the lower back. They compared a group of people with chronic low back pain to a g…
Thoracolumbar fascialow back painshear strain - B2011
The effect of molecular weight on hyaluronan’s cartilage boundary lubricating ability e alone and in combination with proteoglycan 4
J J Kwiecinski, S G Dorosz, T E Ludwig, S Abubacker, Mary K Cowman, T A SchmidtThis study investigated the lubricating ability of hyaluronan (HA) in articular cartilage, focusing on how its molecular weight affects function. Researchers found that higher molecular weight hyaluronan was more effect…
hyaluronanCartilage boundary lubricationProteoglycan 4 (PRG4) - A2011
The extracellular matrix: an active or passive player in fibrosis?
T N Wight, S Potter-PerigoFibrosis, the excessive buildup of scar tissue, can be understood as a wound healing process that has gone awry. Normally, specialized cells called myofibroblasts help repair tissue and then disappear, but in fibrosis,…
fasciaprovisional extracellular matrixmyofibroblatcollagenhyaluronan proteoglycans - B2011
Adhesive capsulitis of the shoulder
Andrew S Neviase, Robert J NeviaserThis clinical overview describes adhesive capsulitis, or "frozen shoulder," a condition marked by painful, progressive loss of shoulder movement due to fibrosis of the joint capsule. The authors note that diagnosis requ…
frozen shoulderAdhesive capsulitis - A2011
Chronic Disease: Are We Missing Something?
James L OschmanThis 2011 editorial by James L. Oschman poses a question in its title: "Chronic Disease: Are We Missing Something?". Without an abstract or full text available for summary, the specific perspective or argument presented…
fasciachronic diseaseearthing