Research.
Every peer-reviewed study on fascia in one place — graded for strength of evidence, summarised in plain language for clinicians, researchers, and curious readers.
We grade studies from A to 1A+++ using the Fascia Research Database rubric — 1A+++ is the strongest.
Researchers behind the studies- A+++2012
Total antioxidant capacity of diet and risk of stroke: a population-based prospective cohort of women
Susanne Rautiainen, Susanna Larsson, Jarmo Virtamo, Alicja WolkThis Swedish population-based study examined the relationship between the total antioxidant capacity of the diet and stroke risk in over 36,000 women. By measuring the combined effect of all antioxidants in food rather…
Antioxidantsstroke - A++2012
Vitamin C transport and its role in the central nervous system
James M MayThis review article explores the critical role of vitamin C in the central nervous system. Although it circulates in the blood at low concentrations, neurons in the brain and spinal cord maintain very high levels of the…
ascorbate transport; brain; dehydroascorbate; glutamate; neurons; SVCT2 - A2011
Remodeling and homeostasis of the extracellular matrix: implications for fibrotic diseases and cancer
Thomas R Cox, Janine T ErlerIn this perspective article, the authors discuss how the extracellular matrix (ECM) is constantly being remodeled, a process essential for normal bodily functions like wound healing and tissue maintenance. When this rem…
fasciaextracellular matrixcancerfibrosisstiffness - B2011
Severe lung fibrosis requires an invasive fibroblast phenotype regulated by hyaluronan and CD44
Yuejuan Li, Dianhua Jiang, Jiurong Liang, Eric B Meltzer, Alice Gray, Riu Miura, Lise Wogensen, Yu Yamaguchi, Paul W No…This study investigated the mechanisms behind severe lung fibrosis, a condition where excessive connective tissue builds up in the lungs. Using a mouse model, researchers found that fibroblasts, a type of connective tis…
hyaluronanCD44fibrosis - A2011
Fascia and the mechanism of acupuncture
Steven Finando, Donna FinandoThis theoretical paper re-evaluates the mechanisms of acupuncture. The authors propose that fascia, the body's connective tissue network, is the structure that explains how acupuncture works. They argue for this model b…
fasciaacupunctureShamPlaceboMechanism - A2011
Correlations Between Fasciology and Yin Yang Doctrine
Hui Tao, Mei-Chun Yu, Hui-Ying Yang, Rong-Mei Qu, Chun Yang, Xin Zhou, Yu Bai, Jing-Peng Wu, Jun Wang, Ou Sha, Lin YuanThis theoretical paper explores correlations between "fasciology," a model based on 3D reconstruction of connective tissue, and the traditional Chinese doctrine of yin and yang. According to fasciology, the body can be…
fasciafasciologyfascial anatomytwo-system theoryyin yang doctrine - A2011
Anatomical Connection Between the Rectus Capitis Posterior Major and the Dura Mater
Frank Scali, Eric S Marsili, Matthew E PontellIn this anatomical study, researchers dissected 13 cadavers to investigate a connection between a deep neck muscle and the dura mater, the protective covering of the spinal cord. In 11 of the 13 specimens, they found a…
fasciacervical spineposterior atlantoaxial interspacerectus capitis posterior majorspinal dura - A2011
High and Low Molecular Weight Hyaluronic Acid Differentially Regulate Human Fibrocyte Differentiation
A S Maharjan, D Pilling, R H GomerFollowing tissue injury, immune cells called monocytes can differentiate into fibrocytes, a cell type involved in healing and fibrosis. This study investigated how different sizes of hyaluronic acid (HA) affect this pro…
hyaluronanfasciafibrocyte differentiationmonocyte - A2011
Chronic Disease: Are We Missing Something?
James L OschmanThis 2011 editorial by James L. Oschman poses a question in its title: "Chronic Disease: Are We Missing Something?". Without an abstract or full text available for summary, the specific perspective or argument presented…
fasciachronic diseaseearthing - B2011
Fascia redefined: anatomical features and technical relevance in fascial flap surgery
Carla Stecco, Cesare Tiengo, Antonio Stecco, Andrea Porzionato, Veronica Macchi, Robert Stern, Raffaele De CaroFascia has traditionally been seen as a passive wrapping, but this review redefines it as a dynamic tissue with its own complex blood supply and innervation. The authors detail the specific characteristics of different…
hyaluronanfasciaConnective tissueaponeurosisFlaps - 1A+++2011
Hyaluronan within fascia in the etiology of myofascial pain
Carla Stecco, R Stern, A Porzionato, V Macchi, S Masiero, Antonio Stecco, R De CaroIn this cadaver and ultrasound study, researchers examined the composition of deep fascia. They identified layers of hyaluronan (HA), a lubricating substance, between the fascia and muscle, as well as between the fascia…
fasciaHyaluronic acidSliding systemLoose connective tissueFasciacyte - C2011
Fasciae anatomy
Carla Stecco, Fabrice DuparcThis entry represents a 2011 publication titled "Fasciae anatomy" by Carla Stecco and Fabrice Duparc. As only the title is available, a detailed summary of its contents, such as its specific focus on fascial layers or c…
fasciaAnatomyfasciae