Research.
Every peer-reviewed study on fascia in one place — graded for strength of evidence, summarised in plain language for clinicians, researchers, and curious readers.
We grade studies from A to 1A+++ using the Fascia Research Database rubric — 1A+++ is the strongest.
Researchers behind the studiesMathematical model of fiber orientation in anisotropic fascia layers at large displacements
Researchers developed a mathematical model to better understand how collagen fibers within fascia change their orientation when the tissue is stretched. The model suggests that fibers already angled away from the direct…
Total antioxidant capacity of diet and risk of stroke: a population-based prospective cohort of women
This Swedish population-based study examined the relationship between the total antioxidant capacity of the diet and stroke risk in over 36,000 women. By measuring the combined effect of all antioxidants in food rather…
Recent Developments in Myofibroblast Biology
This 2012 narrative review summarizes advances in understanding the myofibroblast, a specialized cell crucial for both normal wound healing and the development of fibrotic diseases. The authors discuss how these cells g…
Hyaluronic acid, A key molecule in skin aging
This review article discusses the role of hyaluronic acid (HA) in skin aging. The authors explain that youthful skin's plumpness and resilience are largely due to its high water content, which HA is uniquely able to ret…
Fascia as a body-wide communication system
This abstract proposes that fascia acts as a body-wide communication system. The author draws an analogy to single-celled organisms, like a paramecium, which can perform complex functions without a nervous system by rel…
Nutritional regulation of muscle protein synthesis with resistance exercise: strategies to enhance anabolism
In this 2012 review article, the authors discuss how nutrition can regulate muscle protein synthesis, especially when combined with resistance exercise. Consuming protein (amino acids) stimulates muscle building, an eff…
Primo Vascular System as a New Morphofunctional Integrated System
This narrative review summarizes research on the primo vascular system (PVS), a proposed anatomical network found throughout the body. The authors describe the methods and instruments used to study this system, primaril…
Mechanical properties of human patellar tendon at the hierarchical levels of tendon and fibril
Researchers investigated how the mechanical properties of the whole human patellar tendon compare to its individual collagen fibrils. They tested whole tendons in living subjects and then tested isolated fibrils from th…
Diet-Induced Dysbiosis of the Intestinal Microbiota and the Effects on Immunity and Disease
This 2012 narrative review explores the connection between diet, gut microbes, and the immune system. The gastrointestinal tract must balance tolerance for harmless bacteria and food with responsiveness to pathogens. An…
Real-time imaging of cortical areas involved in the generation of increases in skin sympathetic nerve activity when viewing emotionally charged images
This study investigated which brain regions are involved when our bodies react to emotional images. Researchers simultaneously measured brain activity with fMRI and skin sympathetic nerve activity (SSNA), a marker of th…
Vitamin C transport and its role in the central nervous system
This review article explores the critical role of vitamin C in the central nervous system. Although it circulates in the blood at low concentrations, neurons in the brain and spinal cord maintain very high levels of the…
Hyaluronan injection in murine osteoarthritis prevents TGFbeta 1-induced synovial neovascularization and fibrosis and maintains articular cartilage integrity by a CD44-dependent mechanism
In this mouse study, researchers investigated how hyaluronan (HA) injections might protect joints in osteoarthritis. They found that even though the injected HA was cleared from the knee joint in under two hours, a sing…