Research.
Every peer-reviewed study on fascia in one place — graded for strength of evidence, summarised in plain language for clinicians, researchers, and curious readers.
We grade studies from A to 1A+++ using the Fascia Research Database rubric — 1A+++ is the strongest.
Researchers behind the studies- A2013
Telocytes: ultrastructural, immunohistochemical and electrophysiological characteristics in human myometrium
Sanda M Cretoiu, Dragos Cretoiu, Adela Marin, Beatrice Mihaela Radu, Laurentiu M PopescuThis study identifies a specific cell type, telocytes, within the muscular wall of both the pregnant and non-pregnant human uterus. Researchers found that these cells have a different structure depending on whether the…
telocytesuterine - A2013
Direct magnetic resonance (MR) shoulder arthrography: posterior approach under ultrasonographic guidance and abduction (PAUGA
R F Grasso, E Faiella, P Cimini, R L Cazzato, G Luppi, F Martina, R Del Vescovo, B Beomonte ZobelThis study evaluated a specific technique, called PAUGA, for injecting contrast dye into the shoulder joint before an MRI scan (MR arthrography). Researchers used ultrasound to guide a needle from the back of the should…
ShoulderDirect MR arthrographyUS guidance - A2013
Cellular Control of Connective Tissue Matrix Tension
H M Langevin, M Nedergaard, A HoweThis review article explores how fibroblasts, the cells within connective tissue, actively help regulate tissue tension. Traditionally, the mechanical properties of connective tissue have been attributed to its passive…
Connective tissuefibroblastmechanicalatpcytoskeleton - A2013
Visceral and Somatic Disorders: Tissue Softening with Frequency-Specific Microcurrent
Carolyn R McMakin, James L OschmanThis review article explores a technique called Frequency-Specific Microcurrent (FSM), which uses microampere-level electrical currents to treat various health conditions. A consistent finding is a rapid and palpable so…
fasciafrequency-specific microcurrentvisceral diseasesomatic disease - B2012
Fascia: a morphological description and classification system based on a literature review
Myroslava Kumka, Jason BonarIn this literature review, the authors address the historical problem of ambiguous and inconsistent terminology for fascia. Based on a review of existing research, they propose a new system for classifying fascia accord…
fasciaConnective tissueManual TherapyterminologyAnatomy - A2012
Earthing: Health Implications of Reconnecting the Human Body to the Earth’s Surface Electrons
Gaétan Chevalier, Stephen T Sinatra, James L Oschman, Karol Sokal, Pawel SokalThis 2012 review paper explores the concept of 'earthing' or 'grounding,' which involves direct physical contact with the Earth's surface electrons. The authors propose that modern lifestyles separate humans from this c…
fasciaearthinggroundingearth surface electrons - B2012
Hyaluronan differently modulates TLR-4 and the inflammatory response in mouse chondrocytes
Giuseppe M Campo, Angela Avenoso, Angela D’Ascola, Vera Prestipino, Michele Scuruchi, Giancarlo Nastasi, Alberto Calatr…This study on mouse cartilage cells investigated how different sizes of hyaluronan (HA) affect inflammation. Researchers found that small HA fragments increased the production of several inflammatory markers. In contras…
hyaluronancytokinesNF-kBtoll-like receptor-4chondrocytes - B2012
Mechanical strain applied to human fibroblasts differentially regulates skeletal myoblast differentiation
Michael R Hicks, Thanh V Cao, David H Campbell, Paul R StandleyThis laboratory study investigated how different types of stretching affect muscle repair at a cellular level. Researchers applied two types of strain to human fibroblasts (connective tissue cells) and observed the effe…
myotubescocultureinterleukin-6 - A2012
Mathematical model of fiber orientation in anisotropic fascia layers at large displacements
Hans Chaudhry, Max Roman, Antonio Stecco, Thomas FindleyResearchers developed a mathematical model to better understand how collagen fibers within fascia change their orientation when the tissue is stretched. The model suggests that fibers already angled away from the direct…
Fascial; Reinforcement; Collagen fibers; Re-orientation; Tension - A2012
Real-time imaging of cortical areas involved in the generation of increases in skin sympathetic nerve activity when viewing emotionally charged images
Luke A Henderson, Alexandra Stathis, Cheree James, Rachael Brown, Skye McDonald, Vaughan G MacefieldThis study investigated which brain regions are involved when our bodies react to emotional images. Researchers simultaneously measured brain activity with fMRI and skin sympathetic nerve activity (SSNA), a marker of th…
fasciaMRIIASP imagesmicroneurographyskin sympathetic nerve activity - A+2012
Nutritional regulation of muscle protein synthesis with resistance exercise: strategies to enhance anabolism
Tyler A Churchward-Venne, Nicholas A Burd, Stuart M PhillipsIn this 2012 review article, the authors discuss how nutrition can regulate muscle protein synthesis, especially when combined with resistance exercise. Consuming protein (amino acids) stimulates muscle building, an eff…
MusclenutritionhypertrophyAnabolic intramuscular signaling - A2012
Human myometrium – the ultrastructural 3D network of telocytes
Sanda M Cretoiu, Dragos Cretoiu, Laurentiu M PopescuThis study examined a relatively new type of cell, the telocyte, within the human myometrium, the muscular layer of the uterus. Using advanced microscopy, researchers visualized these cells and their very long extension…
telocytes ! telopodes ! podoms ! podomers ! human uterus ! extracellular vesicles