Research.
Every peer-reviewed study on fascia in one place — graded for strength of evidence, summarised in plain language for clinicians, researchers, and curious readers.
We grade studies from A to 1A+++ using the Fascia Research Database rubric — 1A+++ is the strongest.
Researchers behind the studies- A2013
The Primo Vascular System as a New Anatomical System
Miroslav Stefanov, Michael Potroz, Jungdae Kim, Jake Lim, Richard Cha, Min-Ho NamThis review paper proposes the existence of a "primo vascular system" (PVS) as the physical, anatomical basis for the meridian system of traditional Eastern medicine. According to the authors, this previously unknown sy…
fasciaEvolutioncirculatory systemnew morphologicalfunctional theory - A++2013
Implementation of Matrix Rhythm Therapy and Conventional Massage in Young Females and Comparison of Their Acute Effects on Circulation
Ferruh Taspinar, Ummuhan Bas Aslan, Nuran Sabir, Ugur CavlakThis randomized controlled trial compared the acute effects of Matrix Rhythm Therapy and conventional massage on lower leg blood circulation in young, healthy women. Fifteen participants received a single 30-minute sess…
fascia - 1A+2013
Fascial Components of the Myofascial Pain Syndrome
Antonio Stecco, M Gesi, Carla Stecco, R SternMyofascial pain syndrome (MPS) involves muscle pain and other symptoms linked to trigger points, but the role of fascia is often overlooked. This review summarizes recent research into the biology of fascia to better un…
fasciaHyaluronic aciddensificationMyofascial pain syndrome (MPS)Myofascial trigger - 1A+2013
History of Bioelectrical Study and the Electrophysiology of the Primo Vascular System
Sang Hyun Park, Eung Hwi Kim, Ho Jong Chang, Seung Zhoo Yoon, Ji Woong Yoon, Seong-Jin Cho, Yeon-Hee RyuThis review paper summarizes the history of research on the bioelectrical properties of the primo vascular system (PVS), also known as the Bonghan system. This system has been proposed as a novel circulatory system in t…
primo vascular systemelectrophysiologybioelectrical signals - A2013
Plantar fascia anatomy and its relationship with Achilles tendon and paratenon
Carla Stecco, Marco Corradin, Veronica Macchi, Aldo Morra, Andrea Porzionato, Carlo Biz, Raffaele De CaroThis study investigated the detailed anatomy of the plantar fascia and its connection to the Achilles tendon. Dissections of human cadavers revealed that the fascia is more closely linked to the paratenon (the tendon's…
hyaluronanfasciaFasciacyteachilles tendonparatenon - B2013
Cranial nerves XIII and XIV: nerves in the shadows
Bruno Bordoni, Emiliano ZanierThis narrative review discusses two often-overlooked cranial nerves: the terminal nerve (XIII) and the intermediate nerve (XIV). The authors note that while these nerves have been known for over a century, they are freq…
cranial nervefacial nervetrigeminal systemTolosa-Hunt syndrome - A2013
Primo Vascular System: Past, Present, and Future
Byung-Cheon Lee, Walter J Akers, Xianghong Jing, M Isabel Miguel Perez, Yeonhee RyuAs only the title of this article was available, this summary is necessarily limited. The title, "Primo Vascular System: Past, Present, and Future," suggests this is a review article. It likely covers the history of the…
fasciaprimo vascular systemeditorial - B2013
Hyaluronic acid production and molecular weight improvement by redirection of carbon flux towards its biosynthesis pathway
Mihir V Shah, Sneh S Badle, K B RamachandranResearchers investigated how to optimize the production of hyaluronic acid (HA) in bacteria. In the bacterium *Streptococcus zooepidemicus*, HA production competes for the same nutrients as other processes like cell gro…
Hyaluronic acidMetabolic flux analysisBatch processingBioreactorsProduction kinetics - A+2013
R-Spondin 1 promotes vibration-induced bone formation in mouse models of osteoporosis
Haitao Wang, Tracy A Brennan, Elizabeth Russell, Jung-Hoon Kim, Kevin P Egan, Qijun Chen, Craig Israelite, David C Schu…This animal study on mice investigated how mechanical signals, like vibration, can stimulate bone growth. Researchers identified proteins secreted by mesenchymal progenitor cells (MPCs) in response to vibration. They fo…
Mechanical signals; vibration; R-spondin 1; telomerase; telomere; aging; osteoporosis; mesenchymal stem cells - A+2013
Exercise training initiated in late middle age attenuates cardiac fibrosis and advanced glycation end-product accumulation in senescent rats
Kathryn J Wright, Melissa M Thomas, Andrew C Betik, Darrell Belke, Russell T HeppleThis animal study investigated if exercise started later in life could still benefit the aging heart. Researchers had late middle-aged rats begin treadmill training and continue into old age, comparing them to sedentary…
%BF; AGE; ANOVA; Advanced glycation end-products; Aging; DXA; ECM; ET; Endurance exercise; F344BNF1; Fibrosis; Fischer 344 Brown Norway F1 hybrid rat; GAPDH; Heart; LV; MMP; Matrix metalloproteinases; RT-PCR; TIMP; TTBS; Tris-buffered saline (+0.5% Tween); WGA; advanced glycation end-product; analysis of variance; dual energy X-ray absorptiometry; exercise training; extracellular matrix; glyceraldehyde 3-phosphate dehydrogenase; left ventricle; matrix metalloproteinase; percent body fat; reverse transcription polymerase chain reaction; tissue inhibitor of matrix metalloproteinase; wheat germ agglutinin. - A+++2013
The 17-β-oestradiol inhibits osteoclast activity by increasing the cannabinoid CB2 receptor expression
Francesca Rossi, Giulia Bellini, Livio Luongo, Silvia Mancusi, Marco Torella, Chiara Tortora, Iolanda Manzo, Francesca…This in vitro study investigated how 17-β-oestradiol (estrogen) affects osteoclasts, the cells responsible for bone resorption. The researchers found that estrogen inhibits the formation and activity of these cells by i…
cannabinoidsosteoporosis - A+++2013
Vitamin C Is an Essential Factor on the Anti-viral Immune Responses through the Production of Interferon-α/β at the Initial Stage of Influenza A Virus (H3N2) Infection
Yejin Kim, Hyemin Kim, Seyeon Bae, Jiwon Choi, Sun Young Lim, Naeun Lee, Joo Myung Kong, Young-il Hwang, Jae Seung Kang…This animal study investigated how vitamin C affects the immune response to influenza A virus (H3N2). Researchers used mice that, like humans, cannot synthesize their own vitamin C. When these mice were made vitamin C-d…
immune responseVitamin Cantiviralinfluenza Ainterferon alfa/beta