Research.

Every peer-reviewed study on fascia in one place — graded for strength of evidence, summarised in plain language for clinicians, researchers, and curious readers.

We grade studies from A to 1A+++ using the Fascia Research Database rubric — 1A+++ is the strongest.

Researchers behind the studies

2,806

studies

602

top-graded

2,783

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Showing 817–828 of 954 studies · page 69/80Since 2010 With summary

B
2013
Understanding mechanotransduction and biotensegrity from an adaptation perspective
Leon Chaitow
This article, for which only the title is available, appears to be a conceptual exploration of mechanotransduction and biotensegrity. Mechanotransduction is the process by which cells sense and respond to mechanical for…
Editorial
A
2013
Sensory findings after stimulation of the thoracolumbar fascia with hypertonic saline suggest its contribution to low back pain
Andreas Schilder, Ulrich Hoheisel, Walter Magerl, Justus Benrath, Thomas Klein, Rolf-Detlef Treede
This experimental study investigated the role of the thoracolumbar fascia as a potential source of low back pain. Researchers injected a pain-inducing saline solution into the fascia, back muscles, and subcutaneous tiss…
fasciaThoracolumbar fascialow back painhypertonic salineerector spinae muscle
A
2013
Plantar fascia anatomy and its relationship with Achilles tendon and paratenon
Carla Stecco, Marco Corradin, Veronica Macchi, Aldo Morra, Andrea Porzionato, Carlo Biz, Raffaele De Caro
This study investigated the detailed anatomy of the plantar fascia and its connection to the Achilles tendon. Dissections of human cadavers revealed that the fascia is more closely linked to the paratenon (the tendon's…
hyaluronanfasciaFasciacyteachilles tendonparatenon
A++
2013
Squeeze film lubrication for non-Newtonian fluids with application to manual medicine
Hans Chaudhry, Bruce Bukiet, Max Roman, Antonio Stecco, Thomas Findley
Researchers used a mathematical model to investigate how manual therapy affects the fluid in and around fascia. The model focused on hyaluronic acid (HA), a natural lubricant in connective tissue. The results suggest th…
fasciaHyaluronic acidmassage therapyvibrationsmanual manipulation
A
2013
Purine receptor mediated actin cytoskeleton remodeling of human fibroblasts
Nanna Goldman, Devin Chandler-Militello, Helene Langevin, Maiken Nedergaard, Takahiro Takano
This laboratory study investigated how certain molecules, called purines, affect human fibroblast cells. Previous research has shown that acupuncture can trigger the release of purines like ATP. The researchers exposed…
fasciacytoskeletonacupunctureFibroblastscalcium signaling
A
2013
Molecular assembly and mechanical properties of the extracellular matrix: A fibrous protein perspective
Lisa D Muiznieks, Fred W Keeley
This review article examines the extracellular matrix (ECM), the dynamic network of molecules surrounding our cells. The authors focus on fibrous proteins like collagen and elastin, which form the structural backbone of…
fasciaextracellular matrixcollageneastinself-assembly
C
2013
Heparan sulfate proteoglycan as a cell-surface endocytosis receptor
Helena C Christianson, Mattias Belting
In this review, the authors discuss how large molecules enter the body's cells. They focus on heparan sulfate proteoglycans (HSPGs), a type of molecule on the cell surface that acts as a receptor or docking station. Man…
GlycosaminoglycanExosomesDrug deliveryMacromoleculesMembrane transport
A
2013
Applications and Emerging Trends of Hyaluronic Acid in Tissue Engineering, as a Dermal Filler, and in Osteoarthritis Treatment
Amir Fakhari, Cory Berkland
This narrative review summarizes knowledge about hyaluronic acid (HA), a naturally occurring polymer found in the body's connective tissues and fluids. The authors describe how HA contributes to the structural propertie…
fasciaHyaluronic acidcrosslinkingdermal fillerviscosupplement
A
2013
Hyaluronan: A Simple Polysaccharide with Diverse Biological Functions
Kevin T Dicker, Lisa A Gurski, Swati Pradhan-Bhatt, Robert L Witt, Mary C Farach-Carson, Xinqiao Jia
This review paper describes hyaluronan (HA), a simple sugar molecule found abundantly throughout the body's connective tissues. Despite its simple structure, HA has a surprising array of biological functions. It helps o…
hyaluronanfasciawound healingsynthasehyaluronidase
B
2013
Hyaluronic acid production and molecular weight improvement by redirection of carbon flux towards its biosynthesis pathway
Mihir V Shah, Sneh S Badle, K B Ramachandran
Researchers investigated how to optimize the production of hyaluronic acid (HA) in bacteria. In the bacterium *Streptococcus zooepidemicus*, HA production competes for the same nutrients as other processes like cell gro…
Hyaluronic acidMetabolic flux analysisBatch processingBioreactorsProduction kinetics
1A+
2013
Stress and Matrix-Responsive Cytoskeletal Remodeling in Fibroblasts
R D Abbott, C Koptiuch, J C Iatridis, A K Howe, G J Badger, H M Langevin
In loose connective tissue, fibroblasts change shape in response to static stretch, which helps the tissue relax. This study investigated whether this response depends on the cell itself or its surrounding environment,…
Fibroblasts; cytoskeleton; dense connective tissue; areolar connective tissue; mechanotransduction
A
2013
The Primo Vascular System as a New Anatomical System
Miroslav Stefanov, Michael Potroz, Jungdae Kim, Jake Lim, Richard Cha, Min-Ho Nam
This review paper proposes the existence of a "primo vascular system" (PVS) as the physical, anatomical basis for the meridian system of traditional Eastern medicine. According to the authors, this previously unknown sy…
fasciaEvolutioncirculatory systemnew morphologicalfunctional theory