Research.
Every peer-reviewed study on fascia in one place — graded for strength of evidence, summarised in plain language for clinicians, researchers, and curious readers.
We grade studies from A to 1A+++ using the Fascia Research Database rubric — 1A+++ is the strongest.
Researchers behind the studies- A++2014
Biophoton signal transmission and processing in the brain
Rendong Tang, Jiapei DaiThis narrative review explores an alternative theory of how brain cells communicate. The traditional view is that the nervous system uses bioelectrical and chemical signals, but these models struggle to explain higher b…
biophotonsUltra-weak photon emissionsBiophotonic transmissionNeural signal transmission and processingNeural circuits - A2013
Cellular Control of Connective Tissue Matrix Tension
H M Langevin, M Nedergaard, A HoweThis review article explores how fibroblasts, the cells within connective tissue, actively help regulate tissue tension. Traditionally, the mechanical properties of connective tissue have been attributed to its passive…
Connective tissuefibroblastmechanicalatpcytoskeleton - A+2013
Reduced adipose tissue lymphatic drainage of macromolecules in obese subjects: a possible link between obesity and local tissue inflammation?
N Arngrim, L Simonsen, J J Holst, J BülowResearchers compared lymphatic drainage from abdominal fat tissue in lean and obese men. They measured drainage before and after the men consumed a glucose drink, which mimics the body's response to a meal. In lean men,…
adipose tissue; lymphatic drainage; blood flow; glucose load; obesity; diabetes - A+2013
Local vitamin-C Injection Reduced Tendon Adhesion in a Chicken Model of Flexor Digitorum Profundus Tendon Injury
Leung-Kim Hung, Sai-Chuen Fu, Yuk-Wa Lee, Tsui-Yu Mok, Kai-Ming ChanThis animal study investigated whether vitamin C could reduce scar tissue formation after a tendon injury. Researchers injured a flexor tendon in chickens and then injected either vitamin C or a saline solution at the s…
Vitamin Chealing tendonadhesion - A2013
A pilot study of myofascial release therapy compared to Swedish massage in Fibromyalgia
Ginevra Liptan, Scott Mist, Cheryl Wright, Anna Arzt, Kim Dupree JonesThis small pilot study compared the effects of myofascial release (MFR) and Swedish massage on women with fibromyalgia. Participants received either MFR or Swedish massage for 90 minutes weekly over four weeks. While bo…
fasciaMyofascial releaseFibromyalgiamassage therapycentral sensitization - A+2013
R-Spondin 1 promotes vibration-induced bone formation in mouse models of osteoporosis
Haitao Wang, Tracy A Brennan, Elizabeth Russell, Jung-Hoon Kim, Kevin P Egan, Qijun Chen, Craig Israelite, David C Schu…This animal study on mice investigated how mechanical signals, like vibration, can stimulate bone growth. Researchers identified proteins secreted by mesenchymal progenitor cells (MPCs) in response to vibration. They fo…
Mechanical signals; vibration; R-spondin 1; telomerase; telomere; aging; osteoporosis; mesenchymal stem cells - A2013
Helical Structure of the Cardiac Ventricular Anatomy Assessed by Diffusion Tensor Magnetic Resonance Imaging With Multiresolution Tractography
Ferran Poveda, Debora Gil, Enric Marti, Albert,aluz, Manel Ballester, Francesc CarrerasIn this animal study, researchers used advanced magnetic resonance imaging (MRI) and computer modeling to visualize the complex fiber structure of the heart muscle in dogs. They developed an automated method to trace th…
fasciaheartifdfusion magnetic resonance imagingdiffusion tractographyhelical heart - B2013
Cranial nerves XIII and XIV: nerves in the shadows
Bruno Bordoni, Emiliano ZanierThis narrative review discusses two often-overlooked cranial nerves: the terminal nerve (XIII) and the intermediate nerve (XIV). The authors note that while these nerves have been known for over a century, they are freq…
cranial nervefacial nervetrigeminal systemTolosa-Hunt syndrome - A2013
Cellulite's aetiology: a review
M de la Casa Almeida, Suarez Serrano, J Rebollo Roldán, J J Jiménez RejanoIn this literature review, researchers examined the underlying causes of cellulite. They found that cellulite is a complex phenomenon with many interacting factors, rather than a single cause. The research points to wom…
Connective tissuecellulites - A2013
Telocytes: ultrastructural, immunohistochemical and electrophysiological characteristics in human myometrium
Sanda M Cretoiu, Dragos Cretoiu, Adela Marin, Beatrice Mihaela Radu, Laurentiu M PopescuThis study identifies a specific cell type, telocytes, within the muscular wall of both the pregnant and non-pregnant human uterus. Researchers found that these cells have a different structure depending on whether the…
telocytesuterine - B2013
CCN2: a mechanosignaling sensor modulating integrin-dependent connective tissue remodeling in fibroblasts?
Andrew LeaskMechanical tension is essential for the function and health of connective tissue. In skin fibroblasts, the protein integrin β1 plays a key role in adhesion and in regulating healing and fibrosis (scarring). This theoret…
fibrosismechanotransductionIntegrinsCCN2CTGF - A2013
A Randomized Steady-State Bioavailability Study of Synthetic versus Natural (Kiwifruit-Derived) Vitamin C
Anitra C Carr, Stephanie M Bozonet, Juliet M Pullar, Jeremy W Simcock, Margreet C M VissersThis randomized study investigated whether the body absorbs vitamin C from kiwifruit as effectively as from a synthetic supplement. Thirty-six young men received either half a kiwifruit or an equivalent dose (50 mg) vit…
ascorbate; ascorbic acid; human; plasma; urine; semen; leukocytes; skeletal muscle
