Research.
Every peer-reviewed study on fascia in one place — graded for strength of evidence, summarised in plain language for clinicians, researchers, and curious readers.
We grade studies from A to 1A+++ using the Fascia Research Database rubric — 1A+++ is the strongest.
Researchers behind the studies- A++2014
Oral supplementation of specific collagen peptides has beneficial effects on human skin physiology: a double-blind, placebo-controlled study
E Proksch, D Segger, J Degwert, M Schunck, V Zague, S OesserThis double-blind, placebo-controlled study investigated the effects of daily collagen peptide supplementation in individuals with knee osteoarthritis. Participants received either porcine or bovine collagen, or a place…
skin agingCollagen hydrolysatecollagen peptidesskin health. - A+2014
Neuroimaging and psychophysiological investigation of the link between anxiety, enhanced affective reactivity and interoception in people with joint hypermobility
Núria Mallorquí-Bagué, Sarah N Garfinkel, Miriam Engels, Jessica A Eccles, Guillem Pailhez, Antonio Bulbena, Hugo D Cri…This study investigated the connection between joint hypermobility, anxiety, and interoception (the sense of the body's internal state). Researchers confirmed that hypermobility is associated with higher levels of anxie…
anxiety; emotion; functional magnetic resonance imaging (fMRI); interoception; joint hypermobility; psychology. - A2014
Primary frozen shoulder: brief review of pathology and imaging abnormalities
Kazuya Tamai, Miwa Akutsu, Yuichiro YanoThis narrative review examines the underlying pathology of primary frozen shoulder, a condition causing spontaneous pain and stiffness in the shoulder joint. The authors summarize evidence indicating that the main issue…
frozen shoulderAdhesive capsulitisShoulder painTherapy - A2014
Treatment of Medial Tibial Stress Syndrome according to the Fascial Distortion Model: A Prospective Case Control Study
Christoph Schulze, Susanne Finze, Rainer Bader, Andreas LisonThis prospective case-control study investigated the Fascial Distortion Model (FDM) for treating medial tibial stress syndrome (MTSS), or shin splints. Researchers applied targeted manual techniques to the lower leg fas…
Manual Therapyfasciaefascial distortion model - A2013
Histological analysis of the rectus capitis posterior major’s myodural bridge
Frank Scali, Matthew E Pontell, Dennis E Enix, Ewarld MarshallThis cadaver study investigated a small tissue bridge between a suboccipital muscle (rectus capitis posterior major) and the dura mater, the protective covering of the spinal cord. Using microscopic analysis on tissue f…
fasciacervical spinerectus capitis posterior majorMyodural Bridgecervical dura mater - A2013
Nociception originating from the crural fascia in rats
T Taguchi, M Yasui, A Kubo, M Abe, H Kiyama, A Yamanaka, K MizumuraThis animal study investigated how the crural fascia, the connective tissue around the lower leg muscles, might be a source of pain signals in rats. Researchers found that this fascia is densely populated with nerve fib…
fasciacrural fascianociceptorsactivity-dependent change in conduction velocity (ADCCV)twin pulse difference (TPD) - A2013
Helical Structure of the Cardiac Ventricular Anatomy Assessed by Diffusion Tensor Magnetic Resonance Imaging With Multiresolution Tractography
Ferran Poveda, Debora Gil, Enric Marti, Albert,aluz, Manel Ballester, Francesc CarrerasIn this animal study, researchers used advanced magnetic resonance imaging (MRI) and computer modeling to visualize the complex fiber structure of the heart muscle in dogs. They developed an automated method to trace th…
fasciaheartifdfusion magnetic resonance imagingdiffusion tractographyhelical heart - A2013
Fascia Research Congress Evidence from the 100 year perspective of Andrew Taylor Still
Thomas W Findley, Mona ShalwalaThis review paper examines research from the first three International Fascia Research Congresses through the perspective of Andrew Taylor Still, the founder of osteopathic medicine. Over a century ago, Still described…
fasciaextracellular matrixfibroblastOsteopathic medicinefascia anatomy - A+2013
The effect of acute exercise on collagen turnover in human tendons: influence of prior immobilization period
L Moerch, J Pingel, M Boesen, M Kjaer, Henning LangbergResearchers investigated how a period of immobility affects the Achilles tendon's response to exercise. In this study, eight healthy men had one leg immobilized for two weeks while the other was used normally. Afterward…
Immobilization ! Power Doppler ! Blood flow velocity ! Procollagen type I N-terminal peptide ! Microdialysis - A2013
Dosed Myofascial Release in Three-Dimensional Bioengineered Tendons: Effects on Human Fibroblast Hyperplasia, Hypertrophy, and Cytokine Secretion
Thanh V Cao, Michael R Hicks, David Campbell, Paul R StandleyThis laboratory study investigated how different amounts and durations of simulated myofascial release (MFR) affect lab-grown human tendon tissue. Researchers applied varying degrees of stretch for different lengths of…
fasciamusculoskeletal manipulationsFibroblaststendons - B2013
CCN2: a mechanosignaling sensor modulating integrin-dependent connective tissue remodeling in fibroblasts?
Andrew LeaskMechanical tension is essential for the function and health of connective tissue. In skin fibroblasts, the protein integrin β1 plays a key role in adhesion and in regulating healing and fibrosis (scarring). This theoret…
fibrosismechanotransductionIntegrinsCCN2CTGF - B2013
Understanding mechanotransduction and biotensegrity from an adaptation perspective
Leon ChaitowThis article, for which only the title is available, appears to be a conceptual exploration of mechanotransduction and biotensegrity. Mechanotransduction is the process by which cells sense and respond to mechanical for…
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