Research.
Every peer-reviewed study on fascia in one place — graded for strength of evidence, summarised in plain language for clinicians, researchers, and curious readers.
We grade studies from A to 1A+++ using the Fascia Research Database rubric — 1A+++ is the strongest.
Researchers behind the studies- A++2014
Highly sensitive imaging for ultra-weak photon emission from living organisms
Masaki KobayashiThis review article describes research on ultra-weak photon emission (UPE), also known as biophotons, which is faint light spontaneously emitted from living organisms. This light emission is associated with metabolic pr…
biophotonsUltra-weak photon emissionCCDReactive oxygen speciesImaging - A++2014
Towards whole-body ultra-weak photon counting and imaging with a focus on human beings: A review
Roeland Van Wijk, Eduard P A Van Wijk, Herman A van Wietmarschen, Jan van der GreefIn this review article, the authors describe the history and development of research into ultra-weak photon emission (UPE), the faint light naturally emitted by the human body. The scientific understanding of this pheno…
Ultra-weak photon emissionBiophotonReactive oxygen speciesSystems biologyHuman - A++2014
Biophoton signal transmission and processing in the brain
Rendong Tang, Jiapei DaiThis narrative review explores an alternative theory of how brain cells communicate. The traditional view is that the nervous system uses bioelectrical and chemical signals, but these models struggle to explain higher b…
biophotonsUltra-weak photon emissionsBiophotonic transmissionNeural signal transmission and processingNeural circuits - A++2014
New perspective in cell communication: Potential role of ultra-weak photon emission
Ankush Prasad, Claudio Rossi, Stefania Lamponi, Pavel Pospíšil, Alberto FolettiThis 2014 narrative review explores how cells might communicate with each other. Beyond chemical signals and direct contact, the authors discuss evidence for communication via electromagnetic radiation, specifically ult…
fasciabiophotonsUltra-weak photon emissioncellular interactionbiocommunication - A++2014
Role of reactive oxygen species in ultra-weak photon emission in biological systems
Pavel Pospíšil, Ankush Prasad, Marek RácThis narrative review explores the connection between reactive oxygen species (ROS) and the faint light, or ultra-weak photon emission, that living organisms naturally produce. The authors explain that normal metabolic…
biophotonsChemiluminescenceReactive oxygen specieslipid peroxidationHydroxyl radical - A++2014
Spatiotemporal Imaging of Glutamate-Induced Biophotonic Activities and Transmission in Neural Circuits
Rendong Tang, Jiapei DaiThis study on mouse brain tissue investigated biophotons, which are ultra-weak light emissions from biological systems. Researchers found that applying the neurotransmitter glutamate caused a significant and long-lastin…
fasciabiophotonsultraweak photons - A2014
Mechanotransduction and extracellular matrix homeostasis
Jay D Humphrey, Eric R Dufresne, Martin A SchwartzConnective tissues are dynamic, constantly adapting even at rest. Cells within these tissues continually sense mechanical cues from their environment through a process called mechanotransduction. In response, they maint…
fasciaextracellular matrixIntegrinsmechanosensingmechanoregulation - B2014
Pro-Resolving lipid mediators and Mechanisms in the resolution of acute inflammation
Christopher D Buckley, Derek W Gilroy, Charles N SerhanIn this narrative review, the authors explain that the resolution of inflammation is an active, carefully orchestrated process, not just the passive stopping of an inflammatory response. Specific molecules called specia…
acute inflammationpro-resolving mediators - 1A+2014
Peripheral Mechanisms Contributing to Spasticity and Implications for Treatment
Antonio Stecco, Carla Stecco, P RaghavanThis narrative review explores how changes in connective tissue might contribute to spasticity following a central nervous system injury. The authors suggest that the initial injury can alter the turnover of hyaluronic…
fasciaConnective tissueStrokeCerebral palsyHypertonia - A2014
Definition of the To Be Named Ligament and Vertebrodural Ligament and Their Possible Effects on the Circulation of CSF
Nan Zheng, Xiao-Ying Yuan, Yun-Fei Li, Yan-Yan Chi, Hai-Bin Gao, Xin Zhao, Sheng-Bo Yu, Hong-Jin Sui, John SharkeyIn this cadaver study, researchers investigated connective tissue structures in the upper neck of 30 human specimens. They identified two specific ligaments, the 'to be named ligament' (TBNL) and the vertebrodural ligam…
fasciadura materMyodural Bridgecerebrospinal fluid circulation - A2014
Uptake and intracytoplasmic storage of pigmented particles by human CD34+ stromal cells/telocytes: endocytic property of telocytes
Lucio Díaz-Flores, Ricardo Gutiérrez, M Pino García, Francisco J Sáez, Fernando Aparicio, Lucio Díaz-Flores Jr, Juan F…Researchers investigated whether a specific type of connective tissue cell, called a telocyte, could absorb foreign particles. They examined human colon tissue that had been injected with India ink as a surgical marker.…
CD34+ stromal cells; colon; endocytosis; phagocytosis; skin; telocytes. - 1A+2014
Crosstalk between fibroblasts and inflammatory cells
S Van Linthout, K Miteva, C TschöpeThis narrative review describes how fibroblasts, traditionally seen as passive cells that produce extracellular matrix, are increasingly understood as active key players in the immune system. The authors provide an over…
fibroblastMyofibroblastInnate and adaptive immune responseHeart failure