Research.
Every peer-reviewed study on fascia in one place — graded for strength of evidence, summarised in plain language for clinicians, researchers, and curious readers.
We grade studies from A to 1A+++ using the Fascia Research Database rubric — 1A+++ is the strongest.
Researchers behind the studiesHyaluronan Controls the Deposition of Fibronectin and Collagen and Modulates TGF-β1 Induction of Lung Myofibroblasts
This study investigated how hyaluronan (HA), a key component of the extracellular matrix, influences the formation of myofibroblasts—cells involved in tissue scarring and fibrosis. Researchers observed that while HA lev…
Remodelling the extracellular matrix in development and disease
This narrative review describes the extracellular matrix (ECM), a dynamic network present in all body tissues that undergoes constant remodeling. This remodeling process is crucial for regulating cell functions like pro…
Hyaluronan, inflammation and breast cancer progression
This narrative review explores the link between inflammation, the tissue component hyaluronan (HA), and breast cancer progression. Cancer cells and surrounding host cells can create an inflamed microenvironment that hel…
The Heart, the Brain, and the Regulation of Emotion
This research entry, summarized from its title, appears to explore the relationship between the heart, the brain, and how emotions are managed. It likely discusses how signals from the cardiovascular system, specificall…
Highly sensitive imaging for ultra-weak photon emission from living organisms
This review article describes research on ultra-weak photon emission (UPE), also known as biophotons, which is faint light spontaneously emitted from living organisms. This light emission is associated with metabolic pr…
The Medium of Haptic Perception: A Tensegrity Hypothesis
In this theoretical paper, the authors propose a new hypothesis for how our sense of touch, or haptic perception, works. Unlike other senses that have a clear medium (like air for sound), the haptic system lacks one. Th…
Antioxidants, inflammation and cardiovascular disease
This narrative review explores the links between inflammation, oxidative stress, and cardiovascular disease (CVD). The authors explain that chronic immune activation in CVD leads to high levels of reactive oxygen specie…
Vitamin C in the Treatment and/or Prevention of Obesity
In this 2014 narrative review, the authors examine the relationship between vitamin C and obesity. Obesity is often linked to oxidative stress, which can lead to other health issues like diabetes and cardiovascular dise…
Clinical Relevance of Fascial Tissue and Dysfunctions
Fascia is a continuous network of connective tissue that supports the entire body. Traditionally seen as a passive structure, recent research shows it plays a more active role. Fascia contains contractile elements that…
Ingested hyaluronan moisturizes dry skin
This review article summarizes research on how oral hyaluronan (HA) supplements may influence skin hydration levels. Studies suggest that a daily intake of 120–240 mg of hyaluronic acid can contribute to increased moist…
Mechanisms of Myofascial Pain
This 2014 narrative review discusses the potential causes of myofascial pain. Myofascial pain syndrome is a common condition involving painful trigger points in muscle, but its precise mechanisms are not well understood…
Hyaluronan Synthase 2 Protects Skin Fibroblasts against Apoptosis Induced by Environmental Stress
Skin fibroblasts need to manage environmental stress, such as UV radiation. This study on mouse cells investigated how hyaluronan (HA) and the enzymes that produce it help fibroblasts survive. Researchers found that cel…