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The Fascia Guide
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Research.

Every peer-reviewed study on fascia in one place — graded for strength of evidence, summarised in plain language for clinicians, researchers, and curious readers.

We grade studies from A to 1A+++ using the Fascia Research Database rubric — 1A+++ is the strongest.

Researchers behind the studies
2,806
studies
602
top-graded
2,783
with plain-language summary
TopicAllfascia233extracellular matrix51hyaluronan46inflammation40Connective tissue39mechanotransduction36collagen32Vitamin C31Manual Therapy30acupuncture24
GradeAll1A+++41A++21A+42A++++1A+++317A++236A+84A435
YearAll yearsSince 2020Since 2015Since 2010With summary
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Showing 733–736 of 736 studies · page 62/62Since 2015
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  1. A
    2015

    Comparative effects of vitamin C on the effects of local anesthetics ropivacaine, bupivacaine, and lidocaine on human chondrocytes

    Jun Tian, Yan Li

    Local anesthetics injected into joints can sometimes be harmful to cartilage cells (chondrocytes). This laboratory study investigated the effects of three common anesthetics—ropivacaine, bupivacaine, and lidocaine—on hu…

    Chondrocytes; Vitamin C; Local anesthetics; Ropivacaine; Bupivacaine; Lidocaine
  2. B
    2015

    Hyaluronan Controls the Deposition of Fibronectin and Collagen and Modulates TGF-β1 Induction of Lung Myofibroblasts

    Stephen P Evanko, Susan Potter-Perigo, Loreen J Petty, Gail A Workman, Thomas N Wight

    This study investigated how hyaluronan (HA), a key component of the extracellular matrix, influences the formation of myofibroblasts—cells involved in tissue scarring and fibrosis. Researchers observed that while HA lev…

    hyaluronanMyofibroblastTGF-β14-methyl umbelliferonefibronectin; collagen
  3. A
    2015

    Glycosaminoglycans and Proteoglycans in Palmar Fascia of Patients with Dupuytren

    Priscilla Carneiro Hirai Nascimento, Elsa Yoko Kobayashi, Luiz Guilherme de Saboya Lenzi, João baptista Gomes dos Santo…

    In this experimental study, researchers investigated the role of glycosaminoglycans (GAGs), a type of molecule in connective tissue, in Dupuytren's disease. The team analyzed palmar fascia tissue samples from 23 patient…

    fasciaProteoglycansdupuytren contractureglycosaminoglycans
  4. A
    2015

    Reflections on osteopathic fascia treatment in the peripheral nervous system

    Bruno Bordoni, Giovanni Bordoni

    In this reflective article, the authors discuss the fascia of the peripheral nervous system. They explain that nerves are enclosed in several layers of fascia that must be able to slide, and that impeded sliding can be…

    fasciapainfascial treatmentnerve palpation