Research.
Every peer-reviewed study on fascia in one place — graded for strength of evidence, summarised in plain language for clinicians, researchers, and curious readers.
We grade studies from A to 1A+++ using the Fascia Research Database rubric — 1A+++ is the strongest.
Researchers behind the studiesFruit, vegetable and vitamin C intakes and plasma vitamin C: cross-sectional associations with insulin resistance and glycaemia in 9-10 year-old children
This cross-sectional study of over 2000 children in the UK examined the relationship between vitamin C and risk factors for type 2 diabetes. Researchers found that higher levels of vitamin C in the blood were associated…
The Effects of Vibration and Muscle Fatigue on Trunk Sensorimotor Control in Low Back Pain Patients
This study compared trunk muscle control between people with chronic low back pain (cLBP) and healthy individuals. Researchers found that the cLBP group was less accurate at reproducing a specific amount of force with t…
Size Matters: Molecular Weight Specificity of Hyaluronan Effects in Cell Biology
This narrative review summarizes current knowledge about hyaluronan, a molecule whose biological effects are dependent on its size. Unlike many other molecules, hyaluronan's signaling properties are determined not by ch…
Influence of different intensities of vibration on proliferation and differentiation of human periodontal ligament stem cells
In this laboratory study, researchers investigated how low-magnitude, high-frequency vibration affects stem cells from the human periodontal ligament, the tissue that holds teeth in the jaw. The results suggest that vib…
Collagen Crosslinking Does Not Dictate Stiffness in a Transgenic Mouse Model of Skeletal Muscle Fibrosis
In this animal study on mice, researchers investigated why fibrotic, or scarred, skeletal muscle becomes so stiff. While it is known that fibrosis involves an increase in collagen, the amount of collagen alone does not…
The extracellular matrix: Tools and insights for the “omics” era
This narrative review discusses the extracellular matrix (ECM), the complex network of proteins and molecules that provides structural and chemical support to our cells and tissues. Alterations in the ECM are associated…
Efficacy of phytoestrogens for menopausal symptoms: a meta-analysis and systematic review
This systematic review and meta-analysis of 15 randomized controlled trials examined the effectiveness of plant-based estrogens, known as phytoestrogens, for relieving menopausal symptoms. The findings suggest that phyt…
Investigation of meningomyovertebral structures within the upper cervical epidural space: a sheet plastination study with clinical implications
This cadaver study investigated soft-tissue connections within the epidural space of the upper cervical spine using dissection and a technique called sheet plastination. The researchers found consistent connections wher…
Effects of plant sterols derived from Aloe vera gel on human dermal fibroblasts in vitro and on skin condition in Japanese women
This study investigated how plant sterols from Aloe vera gel affect the skin, using both laboratory tests on human skin cells (fibroblasts) and a clinical trial with women. In the lab, these sterols were found to stimul…
Primo Vascular System: An Endothelial-to-Mesenchymal Potential Transitional Tissue Involved in Gastric Cancer Metastasis
The primo vascular system (PVS) is described as a distinct circulatory network beyond the blood and lymphatic systems. This study investigated the role this system might play in the spread of gastric cancer. The researc…
Primo Vascular System: A Unique Biological System Shifting a Medical Paradigm
This article describes the primo vascular system (PVS), a unique biological system distinct from the arteriovenous and lymphatic systems. Research suggests the PVS has immune and endocrine functions and plays a role in…
Meralgia paresthetica caused by entrapment of the lateral femoral subcutaneous nerve at the fascia lata of the thigh: a case report and literature review
This case report and literature review describe an unusual presentation of meralgia paresthetica, a condition causing numbness and pain in the outer thigh. While the condition typically involves nerve entrapment at the…