Research.
Every peer-reviewed study on fascia in one place — graded for strength of evidence, summarised in plain language for clinicians, researchers, and curious readers.
We grade studies from A to 1A+++ using the Fascia Research Database rubric — 1A+++ is the strongest.
Researchers behind the studies- A++2015
Fruit, vegetable and vitamin C intakes and plasma vitamin C: cross-sectional associations with insulin resistance and glycaemia in 9-10 year-old children
A S Donin, J E Dent, C M Nightingale, N Sattar, C G Owen, A R Rudnicka, M R Perkin, A M Stephen, S A Jebb, D G Cook, P…This cross-sectional study of over 2000 children in the UK examined the relationship between vitamin C and risk factors for type 2 diabetes. Researchers found that higher levels of vitamin C in the blood were associated…
Vitamin Cinsulin resistensglycaemiadiabetes type 2 - A++2015
The Effects of Vibration and Muscle Fatigue on Trunk Sensorimotor Control in Low Back Pain Patients
Jean-Alexandre Boucher, Jacques Abboud, François Nougarou, Martin C Normand, Martin DescarreauxThis study compared trunk muscle control between people with chronic low back pain (cLBP) and healthy individuals. Researchers found that the cLBP group was less accurate at reproducing a specific amount of force with t…
fascialow back painmuscle fatiguevibration - A++2015
Size Matters: Molecular Weight Specificity of Hyaluronan Effects in Cell Biology
Jaime M Cyphert, Carol S Trempus, Stavros GarantziotisThis narrative review summarizes current knowledge about hyaluronan, a molecule whose biological effects are dependent on its size. Unlike many other molecules, hyaluronan's signaling properties are determined not by ch…
hyaluronanCell signalingmolecular size - A++2015
Influence of different intensities of vibration on proliferation and differentiation of human periodontal ligament stem cells
Chunxiang Zhang, Yanqin Lu, Linkun Zhang, Yang Liu, Yi Zhou, Yangxi Chen, Haiyang YuIn this laboratory study, researchers investigated how low-magnitude, high-frequency vibration affects stem cells from the human periodontal ligament, the tissue that holds teeth in the jaw. The results suggest that vib…
Proliferationmechanical vibrationperiodontal ligament stem cellsosteogenesismagnitude - C2015
Collagen Crosslinking Does Not Dictate Stiffness in a Transgenic Mouse Model of Skeletal Muscle Fibrosis
M A Chapman, R Pichika, R L LieberIn this animal study on mice, researchers investigated why fibrotic, or scarred, skeletal muscle becomes so stiff. While it is known that fibrosis involves an increase in collagen, the amount of collagen alone does not…
fibrosisstiffnesscollagen cross-linking - B2015
The extracellular matrix: Tools and insights for the “omics” era
A Nabaa, K R Clauser, H Dingd, C A Whittaker, S A Carrc, R O HynesaThis narrative review discusses the extracellular matrix (ECM), the complex network of proteins and molecules that provides structural and chemical support to our cells and tissues. Alterations in the ECM are associated…
extracellular matrixMatrisomeMatrisomeDBECM atlasBioinformatics - A+++2015
Efficacy of phytoestrogens for menopausal symptoms: a meta-analysis and systematic review
M-N Chen, C-C Lin, C-F LiuThis systematic review and meta-analysis of 15 randomized controlled trials examined the effectiveness of plant-based estrogens, known as phytoestrogens, for relieving menopausal symptoms. The findings suggest that phyt…
CLIMACTERIC; ESTROGEN; HOT FLUSH; ISOFLAVONE; LIGNAN; MENOPAUSE; META-ANALYSIS. - A2015
Investigation of meningomyovertebral structures within the upper cervical epidural space: a sheet plastination study with clinical implications
Frank Scali, Matthew E Pontell, Lance G Nash, Dennis E EnixThis cadaver study investigated soft-tissue connections within the epidural space of the upper cervical spine using dissection and a technique called sheet plastination. The researchers found consistent connections wher…
fasciacervical spineMyodural Bridgedural lacerationsepidural space - A++2015
Effects of plant sterols derived from Aloe vera gel on human dermal fibroblasts in vitro and on skin condition in Japanese women
Miyuki Tanaka, Eriko Misawa, Koji Yamauchi, Fumiaki Abe, Chiaki IshizakiThis study investigated how plant sterols from Aloe vera gel affect the skin, using both laboratory tests on human skin cells (fibroblasts) and a clinical trial with women. In the lab, these sterols were found to stimul…
oral supplementationaloe sterol; collagen; wrinkle - A2015
Primo Vascular System: An Endothelial-to-Mesenchymal Potential Transitional Tissue Involved in Gastric Cancer Metastasis
An Ping, Su Zhendong, Qu Rongmei, Dai Jingxing, Chen Wei, Zhou Zhongyin, Luo Hesheng, Kwang-Sup SohThe primo vascular system (PVS) is described as a distinct circulatory network beyond the blood and lymphatic systems. This study investigated the role this system might play in the spread of gastric cancer. The researc…
fasciacancermetastasisprimo vascular system - A2015
Primo Vascular System: A Unique Biological System Shifting a Medical Paradigm
Bruno Chikly, Paul Roberts, Jörgen QuaghebeurThis article describes the primo vascular system (PVS), a unique biological system distinct from the arteriovenous and lymphatic systems. Research suggests the PVS has immune and endocrine functions and plays a role in…
fasciaprimo vascular system - A++2015
Meralgia paresthetica caused by entrapment of the lateral femoral subcutaneous nerve at the fascia lata of the thigh: a case report and literature review
Yasuyuki Omichi, Ichiro Tonogai, Shinsuke Kaji, Teruaki Sangawa, Koichi SairyoThis case report and literature review describe an unusual presentation of meralgia paresthetica, a condition causing numbness and pain in the outer thigh. While the condition typically involves nerve entrapment at the…
nerve entrapment