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Research.

Every peer-reviewed study on fascia in one place — graded for strength of evidence, summarised in plain language for clinicians, researchers, and curious readers.

We grade studies from A to 1A+++ using the Fascia Research Database rubric — 1A+++ is the strongest.

Researchers behind the studies
2,806
studies
602
top-graded
2,783
with plain-language summary
Showing 601–612 of 1,131 studies · page 51/95
A2016

Cystocele and functional anatomy of the pelvic floor: review and update of the various theories

Géry Lamblin, Emmanuel Delorme, Michel Cosson, Chrystèle Rubod

This narrative review examines different anatomical theories about how the pelvic floor supports the bladder. The researchers summarize that this support involves a complex interplay of the pubocervical fascia, endopelv…

Pelvic floor . Cystocele . Connective tissue . Anatomy . Endopelvic fascia . Pelvic mobility
A++2016

Fascial hierarchies and the relevance of crossed-helical arrangements of collagen to changes in shape; part II: The proposed effect of blood pressure (Traube-Hering-Mayer) waves on the fascia

Graham Scarr

Periodic changes in blood pressure, known as Traube-Hering-Mayer waves, are linked to respiration and nervous system activity. While complex and not fully understood, they can provide valuable clinical information. This…

Arterial pressure waveform; Collagen; Cranial rhythmic impulse; Fascia; Helix; Interstitial fluid flow; Mayer waves; Myofascia; Traube Hering
A+++2016

Ultrasound Evaluation of the Combined Effects of Thoracolumbar Fascia Injury and Movement Restriction in a Porcine Model

James H Bishop, James R Fox, Rhonda Maple, Caitlin Loretan, Gary J Badger, Sharon M Henry, Margaret A Vizzard, Helene M…

This animal study used pigs to investigate how back fascia responds to injury and restricted movement. Researchers created a small injury in the thoracolumbar fascia and also limited movement in some of the pigs for eig…

chronic Low Back Painshear strainimmobilization
A2016

Hyaluronan concentration and size distribution in human knee synovial fluid: variations with age and cartilage degeneration

Michele M Temple-Wong, Shuwen Ren, Phu Quach, Bradley C Hansen, Albert C Chen, Akihiko Hasegawa, Darryl D D’Lima, Jim K…

This study investigated how the lubricant hyaluronan in knee joint fluid changes with age and cartilage wear. Researchers analyzed synovial fluid from human donors aged 23 to 91 without diagnosed osteoarthritis. They fo…

hyaluronanAgingSynovial fluid
A2016

Acute bouts of upper and lower body static and dynamic stretching increase non‑local joint range of motion

David George Behm, Tyler Cavanaugh, Patrick Quigley, Jonathan Christopher Reid, Priscyla Silva Monteiro Nardi, Paulo He…

This study investigated whether stretching one part of the body could increase flexibility in a completely different area. Researchers had participants perform either static or dynamic stretches for their shoulders and,…

Crossover fatigue · Non-local muscle fatigue · Flexibility · Range of motion · Strength · Electromyography
A2016

Hyaluronan production and molecular weight is enhanced in pathway-engineered strains of lactate dehydrogenase-deficient Lactococcus lactis

Mandeep Kaur, Guhan Jayaraman

Researchers are exploring ways to use engineered bacteria to produce hyaluronic acid (HA), but the yield and molecular weight have often been limited. Previous work suggested that excessive lactate production might be t…

Hyaluronic acid molecular weightLactococcus lactisLactate dehydrogenase mutant
1A+2016

Expression of the endocannabinoid receptors in human fascial tissue

Caterina Fede, G Albertin, L Petrelli, M M Sfriso, C Biz, R De Caro, Carla Stecco

Researchers investigated whether human fascia contains cannabinoid receptors, which are part of the body's endocannabinoid system. Taking small tissue samples from volunteers during orthopedic surgery, they analyzed the…

fascia; fascial fibroblasts; endocannabinoid; immunostaining
A+++2016

A Diet Mimicking Fasting Promotes Regeneration and Reduces Autoimmunity and Multiple Sclerosis Symptoms

In Young Choi, Laura Piccio, Patra Childress, Bryan Bollman, Arko Ghosh, Sebastian Brandhorst, Jorge Suarez, Andreas Mi…

This study investigates how a periodic fasting-mimicking diet (FMD) affects symptoms of multiple sclerosis (MS) using mouse models and preliminary human trials. In animal models, the diet reduced inflammation and promot…

Fasting-mimicking diet; Intermittent fasting; Time-restricted eating; autoimmunity; multiple sclerosis
A++2016

Efficacy and tolerability of an undenatured type II collagen supplement in modulating knee osteoarthritis symptoms: a multicenter randomized, double-blind, placebo-controlled study

James P Lugo, Zainulabedin M Saiyed, Nancy E Lane

This randomized, double-blind, placebo-controlled study evaluated the effects of undenatured type II collagen (UC-II) on symptoms of knee osteoarthritis. Over a 180-day period, 191 volunteers received either 40 mg of UC…

osteoarthritisKnee functionT regulatorycell
A+++2016

Fascial Manipulation® for chronic aspecific low back pain: a single blinded randomized controlledtrial.

Mirco Branchini, Francesca Lopopolo, Ernesto Andreoli, Ivano Loreti, Aurélie M Marchand, Antonio Stecco

This randomized controlled trial compared Fascial Manipulation® combined with standard physiotherapy to physiotherapy alone for patients with chronic non-specific low back pain. The group receiving Fascial Manipulation®…

hyaluronanBack PainFascial manipulation
A++2016

Can fascia’s characteristics be influenced by manual therapy

Serge Gracovetsky

This theoretical essay investigates the fundamental properties of collagen, a key component of fascia. The author explores how manual therapy might relate to the necessity of maintaining collagen's strength under load.…

Collagen; Models; MMP; Water
A+++2016

Clinical applications of vibration therapy in orthopaedic practice

Simone Cerciello, Silvio Rossi, Enrico Vison, Katia Corona, Francesco Oliva

This literature review examines the use of vibration therapy in orthopedic practice. Researchers analyzed 71 studies to understand its effects on bone, muscles, and tendons. The review notes that inconsistencies in appl…

RehabilitationAthletesOsteoporosis