Research.
Every peer-reviewed study on fascia in one place — graded for strength of evidence, summarised in plain language for clinicians, researchers, and curious readers.
We grade studies from A to 1A+++ using the Fascia Research Database rubric — 1A+++ is the strongest.
Researchers behind the studiesThe Application of Acoustic Myography in Canine Muscle Function and Performance Testing
This animal study on 11 Labrador dogs used acoustic myography (AMG) to measure muscle activity during walking and trotting. Researchers focused on two muscles, the m. gluteus superficialis and m. longissimus lumborum, t…
The significance of closed kinematic chains to biological movement and dynamic stability
Biomechanical research has long focused on the body as a system of levers, but this review highlights the importance of "closed kinematic chains" (CKCs). These are continuous mechanical loops that couple multiple parts…
Vitamin C–enriched gelatin supplementation before intermittent activity augments collagen synthesis
In a small study involving eight healthy men, researchers investigated the effect of vitamin C-enriched gelatin supplementation before exercise. Participants who consumed 15 grams of gelatin one hour before a short, int…
Therapeutic effectiveness of instrument-assisted soft tissue mobilization for soft tissue injury: mechanisms and practical application
This narrative review explores the mechanisms and practical use of Instrument-Assisted Soft Tissue Mobilization (IASTM) for treating soft tissue injuries. IASTM involves using specialized tools to apply mechanical press…
The nature and biology of basement membranes
This review article discusses the nature and biology of basement membranes. These are thin, flexible sheets of tissue that line and separate different structures in the body. Once thought to be just passive scaffolding,…
S100A4 in cancer progression and metastasis: A systematic review
This systematic review examines the role of the protein S100A4 in cancer progression and metastasis. S100A4 is involved in the epithelial-mesenchymal transition, a key process that allows cancer cells to spread. The aut…
All you need to know about the AIP diet
This article reviews the Autoimmune Protocol (AIP) diet, which aims to reduce inflammation and relieve symptoms of autoimmune disorders. The diet is based on the idea that problems with the gut wall, sometimes called 'l…
Hyaluronan as a therapeutic target in human diseases
This narrative review explores the role of hyaluronan, a major component of the extracellular matrix involved in tissue injury and repair. Its function varies significantly with its size; fragmented hyaluronan can promo…
Art Advancing Science: Filmmaking Leads to Molecular Insights at the Nanoscale
A project that began as an artistic endeavor to create an entertaining short film about fertilization led to the development of a new scientific simulation tool. By integrating physics-based animation software from the…
Biological effects of direct and indirect manipulation of the fascial system. Narrative review
This narrative review explores the biological effects of manual fascial therapies. While osteopathic manipulative treatment (OMT) is clinically effective, its underlying mechanisms are not fully understood. The authors…
Telocytes heterogeneity: From cellular morphology to functional evidence
This review discusses telocytes, a recently identified type of cell found throughout the connective tissue (stroma) of vertebrates. They are characterized by extremely long, thin extensions called telopodes, which form…
Calcium Signaling in Interstitial Cells: Focus on Telocytes
This narrative review describes current knowledge on calcium signaling in a group of cells called interstitial cells, with a special focus on telocytes. These cells and their calcium signals are important for generating…