Research.
Every peer-reviewed study on fascia in one place — graded for strength of evidence, summarised in plain language for clinicians, researchers, and curious readers.
We grade studies from A to 1A+++ using the Fascia Research Database rubric — 1A+++ is the strongest.
Researchers behind the studiesHypovitaminosis C and vitamin C deficiency in critically ill patients despite recommended enteral and parenteral intakes
This study investigated vitamin C levels in 44 critically ill patients in an intensive care unit (ICU). Researchers found that most patients had low vitamin C levels (hypovitaminosis C), and one-third were severely defi…
Molecular insights into prolyl and lysyl hydroxylation of fibrillar collagens in health and disease
This narrative review provides an updated overview of the complex process of creating mature collagen. The formation of collagen fibrils from precursor molecules involves many enzymes and chaperones in a series of steps…
Mechanical properties of a collagen fibril under simulated degradation
This study used computer simulations to investigate how collagen fibrils lose their strength. Researchers modeled three different types of degradation: the removal of cross-links, surface damage, and damage throughout t…
Semimembranosus Muscle Injuries In Sport. A Practical MRI use for Prognosis
This retrospective study investigated whether MRI scans could help predict recovery time for athletes with injuries to the semimembranosus, one of the hamstring muscles. Researchers analyzed MRI scans from 19 athletes,…
Emotions in Motion: Myofascial Interoception
In this perspective piece, the authors argue that the myofascial system is closely linked to our emotional state. They suggest that manual treatment not only affects the body physically but also activates the interocept…
Mitochondrial dysfunction in the APP/PSEN1 mouse model of Alzheimer’s disease and a novel protective role for ascorbate
In this animal study, researchers examined mitochondrial function in a mouse model of Alzheimer's disease and in mice with low levels of vitamin C (ascorbate). The results indicated that both the presence of amyloid (as…
Effects of the menstrual cycle on lower-limb biomechanics, neuromuscular control, and anterior cruciate ligament injury risk: a systematic review
This systematic review evaluated how the menstrual cycle affects lower-limb biomechanics, neuromuscular control, and anterior cruciate ligament (ACL) injury risk in women. The authors found strong evidence that the risk…
Minimizing Injury and Maximizing Return to Play: Lessons from Engineered Ligaments
Musculoskeletal injuries are a primary reason for time away from sports, partly because our understanding of how training affects tendons and ligaments is limited. This study used engineered ligaments grown in a lab fro…
S100A4 in cancer progression and metastasis: A systematic review
This systematic review examines the role of the protein S100A4 in cancer progression and metastasis. S100A4 is involved in the epithelial-mesenchymal transition, a key process that allows cancer cells to spread. The aut…
All you need to know about the AIP diet
This article reviews the Autoimmune Protocol (AIP) diet, which aims to reduce inflammation and relieve symptoms of autoimmune disorders. The diet is based on the idea that problems with the gut wall, sometimes called 'l…
Art Advancing Science: Filmmaking Leads to Molecular Insights at the Nanoscale
A project that began as an artistic endeavor to create an entertaining short film about fertilization led to the development of a new scientific simulation tool. By integrating physics-based animation software from the…
The nature and biology of basement membranes
This review article discusses the nature and biology of basement membranes. These are thin, flexible sheets of tissue that line and separate different structures in the body. Once thought to be just passive scaffolding,…