Research.
Every peer-reviewed study on fascia in one place — graded for strength of evidence, summarised in plain language for clinicians, researchers, and curious readers.
We grade studies from A to 1A+++ using the Fascia Research Database rubric — 1A+++ is the strongest.
Researchers behind the studies- B2017
Evaluation of fascial manipulation in carpal tunnel syndrome
Marco Pintucci, Marta Imamura, Aurore Thibaut, Lucas M de Exel Nunes, Mylene Mayumi Nagato, Helena H Kaziyama, Satiko T…Details for this study are not yet available. The research, published in 2017, appears to evaluate the effectiveness of Fascial Manipulation® for treating carpal tunnel syndrome. Without an abstract, further details abo…
Fascial manipulationcarpal tunnel syndrome - B2017
Stretching Reduces Skin Thickness and Improves Subcutaneous Tissue Mobility in a Murine Model of Systemic Sclerosis
Y Xiong, L Berrueta, K Urso, Sara Olenich, Igla Muskaj, G J Badger, A Aliprantis, R Lafyatis, H M LangevinThis animal study investigated the effects of stretching on systemic sclerosis, a condition that causes skin inflammation and fibrosis. Using a mouse model of the disease, researchers found that ten minutes of daily str…
inflammationfibrosisSystemic sclerosisStretchingscleroderma - A2017
Art Advancing Science: Filmmaking Leads to Molecular Insights at the Nanoscale
Charles Reilly, Donald E IngberA project that began as an artistic endeavor to create an entertaining short film about fertilization led to the development of a new scientific simulation tool. By integrating physics-based animation software from the…
Tensegritysimulationanimationaxonemedynein - A2017
Don’t Forget the Abdominal Wall: Imaging Spectrum of Abdominal Wall Injuries after Nonpenetrating Trauma
Shanna A Matalon, Reza Askari, Jonathan D Gates, Ketan Patel, Aaron D Sodickson, Bharti KhuranaAbdominal wall injuries from non-penetrating trauma are relatively common but are often overlooked in the emergency department. This can happen because more severe, distracting injuries draw attention away, or because t…
abdominal wallabdominal wall injuriesabdominal wall herniaabdominal wall muscle injurycostochondral rib injury - A+2017
Quantitative tissue parameters of Achilles tendon and plantar fascia in healthy subjects using a handheld myotonometer
Sarah Orner, Wolfgang Kratzer, Julian Schmidberger, Beate GrünerThis study examined the mechanical properties of the Achilles tendon and plantar fascia in over 150 healthy adults using a handheld device called a MyotonPRO. The goal was to establish baseline normal values for tissue…
fasciaachilles tendonplantar fasciaMyotonePRO - A++2017
Biological effects of direct and indirect manipulation of the fascial system. Narrative review
Giovanni Parravicini, Andrea BergnaThis narrative review explores the biological effects of manual fascial therapies. While osteopathic manipulative treatment (OMT) is clinically effective, its underlying mechanisms are not fully understood. The authors…
fasciaMyofascial releaseManual TherapyMyofascial manipulation - A++2017
Telocytes: Connective tissue repair and communication cells
Leon ChaitowThis commentary highlights a newly identified type of connective tissue cell called a telocyte. We already know that other cells, like fibroblasts, respond to mechanical forces from manual therapy, influencing tissue re…
mechanotransductiontelocytesinterstitial cellsregeneration - A2017
What's in a name: Myofascial Release or Myofascial Induction?
Leon ChaitowThis commentary discusses two terms for a similar manual therapy technique: Myofascial Release (MFR) and Myofascial Induction Therapy (MIT). The author notes that while the techniques are virtually identical, the names…
Myofascial releaseMyofascial Induction therapy - A+2017
Oxidative Stress and Endometriosis: A Systematic Review of the Literature
Gennaro Scutiero, Piergiorgio Iannone, Giulia Bernardi, Gloria Bonaccorsi, Savino Spadaro, Carlo Alberto Volta, Pantale…This systematic review explores the connection between oxidative stress and endometriosis, a condition where uterine-like tissue grows outside the uterus, causing pain and infertility. Oxidative stress is an imbalance b…
Oxidative stressendometriosisROS - A2017
Implications of immune dysfunction on endometriosis associated infertility
Jessica E Miller, Soo Hyun Ahn, Stephany P Monsanto, Kasra Khalaj, Madhuri Koti, Chandrakant TayadeThis literature review explores the link between endometriosis and infertility, a common issue for which the cause is not fully understood. The authors suggest that dysfunction in the immune system plays a significant r…
cytokines; endometriosis; infertility; inflammation; oxidative stress. - A2017
Vitamin C for preventing atrial fibrillation in high risk patients: a systematic review and meta-analysis
Harri Hemilä, Timo SuonsyrjäThis systematic review and meta-analysis examined 15 trials to see if vitamin C could prevent atrial fibrillation in high-risk patients. The analysis, involving over 2000 subjects, found inconsistent results depending o…
Ascorbic acidantioxidantArrhythmiaAtrial fibrillationCardiac surgery - A++2017
Vitamin C and Immune Function
Anitra C Carr, Silvia MagginiThis narrative review explores the crucial role of Vitamin C in the human immune system. As a potent antioxidant, it supports various functions in both the innate and adaptive immune responses, from strengthening the sk…
ascorbate; ascorbic acid; immunity; immune system; neutrophil function; microbial killing; lymphocytes; infection; vitamin C