Research.

Every peer-reviewed study on fascia in one place — graded for strength of evidence, summarised in plain language for clinicians, researchers, and curious readers.

We grade studies from A to 1A+++ using the Fascia Research Database rubric — 1A+++ is the strongest.

Researchers behind the studies

2,806

studies

602

top-graded

2,783

with plain-language summary

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Showing 469–480 of 954 studies · page 40/80Since 2010 With summary

B
2018
Effectiveness of sodium bicarbonate infusion on mortality in septic patients with metabolic acidosis
Zhongheng Zhang, Carlie Zhu, Lei Mo, Yucai Hong
This retrospective database study investigated whether sodium bicarbonate infusion affected mortality in septic patients with metabolic acidosis. The researchers found no overall survival benefit in the general populati…
sepsiscritical careSodium bicarbonateMortalityMarginal structural Cox
A+
2018
Endogenous systems involved in exercise-induced analgesia
R DA SILVA SANTOS, G GALDINO
This narrative review describes the phenomenon of exercise-induced analgesia, which is the pain-relieving effect of physical activity. Studied since the 1970s, this effect is seen in both endurance and resistance exerci…
EndocannabinoidspainexerciseNitric oxideanalgesia
B
2018
Global Expression Profiling Identifies a Novel Hyaluronan Synthases 2 Gene in the Pathogenesis of Lower Extremity Varicose Veins
Chia-Shan Hsieh, Chia-Ti Tsai, Yau-Hung Chen, Sheng-Nan Chang, Juey-Jen Hwang, Eric Y Chuang, I-HuiWu
Researchers investigated the genetic factors behind varicose veins by comparing vein tissue from patients with and without the condition. They found that the gene hyaluronan synthase 2 (HAS2) was significantly less acti…
varicose veins; HAS2; RNA seq
A++
2018
Assessment of pain quality reveals distinct differences between nociceptive innervation of low back fascia and muscle in humans
Andreas Schilder, Walter Magerl, Thomas Klein, Rolf-Detlef Treede
This study explored whether pain from low back muscles is perceived differently than pain from the overlying fascia. Researchers used electrical stimulation in 16 healthy participants, who then described the induced pai…
Thoracolumbar fasciamultifidus musclePain qualityElectrical stimulationVerbal descriptors
A+++
2018
Applied Myo-Fascial Advances in Veterinary Medicine and Practice
A P Harrison, V S Elbrønd
This review article summarizes recent advances in veterinary medicine with a focus on myofascia. It presents findings on the structure and function of these interconnected tissues, highlighting the benefits of treating…
acoustic myography; kinetic lines; bioimpedance; acupuncture; release therapy
A
2018
Treatment for cellulite
Neil Sadick
This brief review summarizes the scientific evidence for various treatments for cellulite, a condition present in 80% to 90% of post-pubertal women. The author examines the safety and efficacy of methods ranging from to…
Cellulite pathophysiology adipocytes radiofrequency lasers
1A+++
2018
Emission of Biophotons and Adjustable Sounds by the Fascial System: Review and Reflections for Manual Therapy
Bruno Bordoni, F Marelli, B Morabito, B Sacconi
In this narrative review, the authors explore how fascia, the web of connective tissue enveloping everything in the body, might communicate. They discuss research suggesting the fascial system may emit faint light parti…
fasciaMuscleManual TherapyMyofascialOsteopathic
A
2018
A fundamental critique of the fascial distortion model and its application in clinical practice
Christoph Thalhamer
This narrative review critiques the Fascial Distortion Model (FDM), a manual therapy approach based on the idea that all musculoskeletal complaints stem from distortions of fascia. The author investigated the scientific…
Manual Therapyfasciaefascial distortion modelreductionismtypaldos
A+++
2018
Structure and Distribution of an Unrecognized Interstitium in Human Tissues
Petros C Benias, Rebecca G Wells, Bridget Sackey-Aboagye, Heather Klavan, Jason Reidy, Darren Buonocore, Markus Miranda…
Using a new imaging technique, researchers identified a previously unrecognized, fluid-filled structure within the body's connective tissues. This network of collagen bundles and fluid-filled spaces, which they term the…
interstitiuminterstitial spacesfascia fluid
A
2018
Lipedema
Caitriona Canning, John R Bartholomew
A detailed summary of this 2018 publication by Caitriona Canning and John R. Bartholomew is not yet available. The work is titled simply 'Lipedema,' suggesting it may be a general overview or review of the condition. Wi…
lipedemalipoedemalipolymphedemavascular medicine
A+++
2018
Low-Intensity Vibration Improves Muscle Healing in a Mouse Model of Laceration Injury
Thomas F Corbiere, Eileen M Weinheimer-Haus, Stefan Judex, Timothy J Koh
In this animal study, researchers investigated if low-intensity vibration (LIV) could improve healing of lacerated calf muscles in mice. The mice were divided into groups that received daily vibration treatment and a co…
skeletal muscle injury; laceration; low-intensity vibration; muscle regeneration; fibrosis
A++
2018
Low-frequency vibrotherapy considerably improves the effectiveness of manual lymphatic drainage (MLD) in patients with lipedema: A two-armed, randomized, controlled pragmatic trial
Rainer Schneider
This randomized controlled trial investigated the effect of adding low-frequency vibrotherapy to manual lymphatic drainage (MLD) for 30 women with stage 2–3 lipedema. Participants were randomly assigned to receive eithe…
Lipedema; MLD; quality of life; shock wave vibrotherapy