Research.
Every peer-reviewed study on fascia in one place — graded for strength of evidence, summarised in plain language for clinicians, researchers, and curious readers.
We grade studies from A to 1A+++ using the Fascia Research Database rubric — 1A+++ is the strongest.
Researchers behind the studies- A2018
The influence of breathing on the central nervous system
Bruno Bordoni, Shahin Purgol, Annalisa Bizzarri, Maddalena Modica, Bruno MorabitoThis narrative review explores the diaphragm's extensive influence on the central nervous system. The authors discuss how the rhythm of our breath can physically move the brain, alter patterns of neural oscillation, and…
diaphragmbreathingphrenic nervevagus nerveneural oscillation - A2018
Neuroinflammation and central sensitization in chronic and widespread pain
Ru-Rong Ji, Andrea Nackley, Yul Huh, Niccolò Terrando, William MaixnerChronic pain is partly maintained by central sensitization, a state where the nervous system becomes hypersensitive. This review discusses how neuroinflammation—inflammation in the nervous system—contributes to this pro…
inflammationchronic paainneuroinflammationsensitization - 1A+2018
From mechanobiology to developmentally inspired engineering
Donald IngberThis review article, based on a lecture, explores the field of mechanobiology, which studies the central role of physical forces in development and physiology. The author reviews 40 years of his laboratory's foundationa…
Tensegritymechanicalorgans-on-chipstissue engineering - A2018
The anatomical relationships of the tongue with the body system
Bruno Bordoni, Bruno Morabito, Roberto Mitrano, Marta Simonelli, Anastasia ToccafondiIn this review article, the authors examine the tongue's functions and its anatomical connections to the rest of the body. The tongue is not only essential for swallowing, breathing, and speaking, but it also affects po…
fasciadiaphragmphysiotherapytonguespeech therapy - A2018
Frontiers in fascia research
Carla Alessandra Avila Gonzalez, Mark Driscoll, Robert Schleip, Scott Wearing, Eric Jacobson, Thomas Findley, Werner Kl…This article reviews recent developments in fascia research, emphasizing new ways to assess this highly variable tissue. Researchers note that fascia differs greatly between individuals in density, stiffness, and metabo…
fasciaultrasound.Pain therapySport sciencesIndentometry - A2018
Measuring the Human Ultra-Weak Photon Emission Distribution Using an Electron-Multiplying, Charge-Coupled Device as a Sensor
Fernando Ortega-Ojeda, Matías Calcerrada, Alejandro Ferrero, Joaquín Campos, Carmen Garcia-RuizLiving systems, including humans, emit an extremely faint light called ultra-weak photon emission (UPE). This light is thought to be a byproduct of metabolic processes, particularly those involving reactive oxygen speci…
ultra-weak photon emission; spectrometer; measurement; electron multiplying charge coupled device sensor; liquid crystal tunable filter - A2018
Effectiveness of Physiotherapy Treatment for Urinary Incontinence in Women: A Systematic Review
Remedios López-Liria, María de los Ángeles Varverde-Martínez, David Padilla-Góngora, Patricia Rocamora-PérezThis systematic review evaluated the effectiveness of different physiotherapy techniques for treating urinary incontinence in women. Researchers analyzed 16 studies covering methods such as pelvic floor exercises, vagin…
physiotherapywomenurinary incontinencepelvic floor muscle - A2018
Pathobiology of cigarette smoke-induced invasive cancer of the renal pelvis and its prevention by vitamin C
Shinjini Ganguly, Ayan Chandra, Indu B ChatterjeeIn this animal study, researchers investigated how cigarette smoke might cause invasive cancer of the renal pelvis and if vitamin C could offer protection. They found that when guinea pigs were exposed to cigarette smok…
Invasive cancer of the renal pelvis Cigarette smoke Vitamin C Oxidative damage Persistent EGFR signaling Cell cycle deregulation - C2018
Sweet, yet underappreciated: Proteoglycans and extracellular matrix remodeling in heart disease
Geir Christensen, Kate M Heruma, Ida G LundeIn this review article, the authors discuss the role of proteoglycans in heart disease. Remodeling of the heart's extracellular matrix, which is common in several cardiac diseases, can lead to fibrosis and impaired func…
extracellular matrixHeart failureheartProteoglycansSyndecan - A2018
Meaning of the Solid and Liquid Fascia to Reconsider the Model of Biotensegrity
Bruno Bordoni, David Lintonbon, Bruno MorabitoThis theoretical article proposes a reconsideration of the traditional biotensegrity model. The authors argue that fascia should be viewed as a system with both solid and liquid components, where blood and lymph constit…
fasciaChiropracticManual TherapyMyofascialOsteopathic - A2018
Effectiveness of 3-dimensional shoulder ultrasound in the diagnosis of rotator cuff tears
Aiping Teng, Fanxiao Liu, Dongsheng Zhou, Tao He, Yan Chevalier, Roland M KlarIn this meta-analysis, researchers combined data from seven studies involving 282 patients to evaluate the effectiveness of 3-dimensional (3D) ultrasound in diagnosing rotator cuff tears. The analysis found that 3D ultr…
3-dimensional ultrasounddiagnostic valuemeta-analysisrotator cuff tears - A2018
Treatment for cellulite
Neil SadickThis brief review summarizes the scientific evidence for various treatments for cellulite, a condition present in 80% to 90% of post-pubertal women. The author examines the safety and efficacy of methods ranging from to…
Cellulite pathophysiology adipocytes radiofrequency lasers
