Research.
Every peer-reviewed study on fascia in one place — graded for strength of evidence, summarised in plain language for clinicians, researchers, and curious readers.
We grade studies from A to 1A+++ using the Fascia Research Database rubric — 1A+++ is the strongest.
Researchers behind the studies- A2018
Lipedema
Caitriona Canning, John R BartholomewA detailed summary of this 2018 publication by Caitriona Canning and John R. Bartholomew is not yet available. The work is titled simply 'Lipedema,' suggesting it may be a general overview or review of the condition. Wi…
lipedemalipoedemalipolymphedemavascular medicine - A+++2018
Cannabis sativa L. and Nonpsychoactive Cannabinoids: Their Chemistry and Role against Oxidative Stress, Inflammation, and Cancer
Federica Pellati, Vittoria Borgonetti, Virginia Brighenti, Marco Biagi, Stefania Benvenuti, Lorenzo CorsiThis narrative review explores the chemical properties and health effects of non-psychoactive compounds found in hemp (Cannabis sativa L.), focusing primarily on cannabidiol (CBD). The research suggests that CBD acts as…
cancerCannabinoidsOxidative stressiflammation - A2018
Variations in Contents of Hyaluronan in the Peritumoral Micro-Environment of Human Chondrosarcoma
Caterina Fede, Carla Stecco, Andrea Angelini, Chenglei Fan, Elisa Belluzzi, Assunta Pozzuoli, Pietro Ruggieri, Raffaele…The micro-environment surrounding a tumor greatly influences its growth and response to therapy. This study focused on chondrosarcoma, a type of bone cancer resistant to both chemotherapy and radiation. Researchers quan…
hyaluronan; chondrosarcoma; peritumoral stroma; fascia; tumor micro-environment; malignant bone tumor; grade - A++2018
Vitamin C – A new player in regulation of the cancer epigenome
Linn Gillberg, Andreas D Ørskov, Minmin Liu, Laurine B S Harsløf, Peter A Jones, Kirsten GrønbækThis narrative review explores the emerging role of vitamin C in cancer treatment, particularly in relation to epigenetics. The authors note that vitamin C is crucial for enzymes that help regulate gene expression, and…
Ascorbic acid; Cancer treatment; Epigenetics; Hematological malignancies; Vitamin C - A2018
The myodural bridges’ existence in the sperm whale
Pei Liu, Chan Li, Nan Zheng, Xiaoying Yuan, Yutong Zhou, Pu Chun, Yanyan Chi, Campbell Gilmore, Shengbo Yu, Hongjin SuiIn this anatomical animal study, researchers examined tissue from a sperm whale to see if it possessed a myodural bridge, a connection between the neck muscles and the dura mater previously identified in humans. The inv…
Myodural Bridge - A2018
Frontiers in fascia research
Carla Alessandra Avila Gonzalez, Mark Driscoll, Robert Schleip, Scott Wearing, Eric Jacobson, Thomas Findley, Werner Kl…This article reviews recent developments in fascia research, emphasizing new ways to assess this highly variable tissue. Researchers note that fascia differs greatly between individuals in density, stiffness, and metabo…
fasciaultrasound.Pain therapySport sciencesIndentometry - A2018
Fascial preadipocytes: another missing piece of the puzzle to understand fibromyalgia?
Bruno Bordoni, Fabiola Marelli, Bruno Morabito, Francesca Cavallaro, David LintonbonIn this review paper, the authors discuss fibromyalgia, a chronic pain condition whose cause remains uncertain. While often linked to changes in the central nervous system, research also points to peripheral nerve damag…
fasciaFibromyalgiapainMyofascialneuropathic pain - A2018
Morphological evidence of telocytes in human synovium
Irene Rosa, Mirca Marini, Daniele Guasti, Lidia Ibba-Manneschi, Mirko ManettiA relatively new type of cell, called a telocyte, has been found in many human tissues. This study was the first to look for and find these cells in the synovial membrane, which is the lining of our movable joints. Usin…
telocytessynovium - A2018
What Is the Point? The Problem with Acupuncture Research That No One Wants to Talk About
Helene M Langevin, Peter M WayneIn this 2018 commentary, the authors address a persistent criticism of acupuncture research: the unclear scientific basis for "acupuncture points." They argue that the acupuncture research community has not paid enough…
acupunctureAnatomyacupuncture pointsmethodology - C2018
Small leucine-rich proteoglycans and matrix metalloproteinase-14: Key partners?
Katarzyna Pietraszek-Gremplewicz, Konstantina Karamanou, Aïchata Niang, Manuel Dauchez, Nicolas Belloy, François-Xavier…This narrative review summarizes research on a family of proteins called small leucine-rich proteoglycans (SLRPs). These proteins are important regulators of the extracellular matrix and have been identified as potentia…
fibromodulinSLRPsLumicanDecorinBiglycan - A++2018
The Impedance Profile of Acupuncture Points
Fletcher KovichThis study investigated real-time electrical impedance (resistance) at acupuncture points in a single subject. The researcher observed that when impedance decreased at the center of a point, it often increased at a loca…
acupunctureacupointsimpedancecommunication - A+++2018
Low-Intensity Vibration Improves Muscle Healing in a Mouse Model of Laceration Injury
Thomas F Corbiere, Eileen M Weinheimer-Haus, Stefan Judex, Timothy J KohIn this animal study, researchers investigated if low-intensity vibration (LIV) could improve healing of lacerated calf muscles in mice. The mice were divided into groups that received daily vibration treatment and a co…
skeletal muscle injury; laceration; low-intensity vibration; muscle regeneration; fibrosis