Research.

Every peer-reviewed study on fascia in one place — graded for strength of evidence, summarised in plain language for clinicians, researchers, and curious readers.

We grade studies from A to 1A+++ using the Fascia Research Database rubric — 1A+++ is the strongest.

Researchers behind the studies

2,806

studies

602

top-graded

2,783

with plain-language summary

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Showing 397–408 of 954 studies · page 34/80Since 2010 With summary

A
2018
Hyaluronan in adipogenesis, adipose tissue physiology and systemic metabolism
Yi Zhu, llja L Kruglikov, Yucel Akgul, Philipp E Scherer
This narrative review summarizes research on hyaluronic acid (HA), a sugar molecule abundant in the body's extracellular matrix. The functions of HA are largely dictated by its molecular size, and it is commonly used as…
HA
A
2018
Orientation and property of fibers of the myodural bridge in humans
Nan Zheng, Yan-Yan Chi, Xiao-Han Yang, Nan-Xing Wang, Yi-Lin Li, Yang-Yang Ge, Lan-Xin Zhang, Tai-Yuan Liu, Xiao-Ying Y…
The myodural bridge is a fibrous connection between the deep suboccipital muscles of the neck and the spinal dura mater, the tough outer covering of the spinal cord. In this anatomical study, researchers investigated th…
Atlanto-axial interspace; Atlanto-occipital interspace; Collagen I fibers; Histologic staining; Myodural bridge; Suboccipital muscles; Vertebral dural ligament
A
2018
Effectiveness of 3-dimensional shoulder ultrasound in the diagnosis of rotator cuff tears
Aiping Teng, Fanxiao Liu, Dongsheng Zhou, Tao He, Yan Chevalier, Roland M Klar
In this meta-analysis, researchers combined data from seven studies involving 282 patients to evaluate the effectiveness of 3-dimensional (3D) ultrasound in diagnosing rotator cuff tears. The analysis found that 3D ultr…
3-dimensional ultrasounddiagnostic valuemeta-analysisrotator cuff tears
B
2018
The Receptor for Hyaluronan- Mediated Motility (CD168) promotes inflammation and fibrosis after acute lung injury
Zheng Cui, Jie Liao, Naeun Cheongb, Christopher Longoria, Gaoyuan Cao, Horace M DeLisser, Rashmin C Savani
In this animal study, researchers investigated the role of a specific receptor, RHAMM, in the body's response to acute lung injury. Using mouse models, they compared outcomes in mice that lacked the RHAMM receptor to th…
HA
B
2018
Global Expression Profiling Identifies a Novel Hyaluronan Synthases 2 Gene in the Pathogenesis of Lower Extremity Varicose Veins
Chia-Shan Hsieh, Chia-Ti Tsai, Yau-Hung Chen, Sheng-Nan Chang, Juey-Jen Hwang, Eric Y Chuang, I-HuiWu
Researchers investigated the genetic factors behind varicose veins by comparing vein tissue from patients with and without the condition. They found that the gene hyaluronan synthase 2 (HAS2) was significantly less acti…
varicose veins; HAS2; RNA seq
A
2018
Muscle spindles of the rat sternomastoid muscle
Walter Giuriati, Barbara Ravara, Andrea Porzionato, Giovanna Albertin, Carla Stecco, Veronica Macchi, Raffaele De Caro,…
This animal study on rats examined the sternomastoid muscle in the neck, which has a unique structure. Researchers found it has two distinct regions: a superficial "white" part with fast-twitch fibers and a deep "red" p…
ratsternomastoid musclemuscle spindlesfiber typestranslational studies
A
2018
Morphological evidence of telocytes in human synovium
Irene Rosa, Mirca Marini, Daniele Guasti, Lidia Ibba-Manneschi, Mirko Manetti
A relatively new type of cell, called a telocyte, has been found in many human tissues. This study was the first to look for and find these cells in the synovial membrane, which is the lining of our movable joints. Usin…
telocytessynovium
C
2018
Anatomy of the fasciae and fascial spaces of the maxillofacial and the anterior neck regions
Seiichiro Kitamura
This narrative review simplifies the complex anatomy of the fascia in the face, jaw, and front of the neck. The author organizes the region into four distinct portions based on their relationship to a key fascial layer,…
fasciaFascial spaceGross anatomyMaxillofacial regionAnterior neck
A
2018
Low Back Pain: The Potential Contribution of Supraspinal Motor Control and Proprioception
Michael Lukas Meier, Andrea Vrana, Petra Schweinhardt
This narrative review explores how motor control—the brain's management of posture and movement—adapts in people with low back pain. While these movement adaptations may reduce pain in the short term, they can sometimes…
proprioceptionlow back painmotor controlchronic painmotor cortex
A
2018
Variations in Contents of Hyaluronan in the Peritumoral Micro-Environment of Human Chondrosarcoma
Caterina Fede, Carla Stecco, Andrea Angelini, Chenglei Fan, Elisa Belluzzi, Assunta Pozzuoli, Pietro Ruggieri, Raffaele…
The micro-environment surrounding a tumor greatly influences its growth and response to therapy. This study focused on chondrosarcoma, a type of bone cancer resistant to both chemotherapy and radiation. Researchers quan…
hyaluronan; chondrosarcoma; peritumoral stroma; fascia; tumor micro-environment; malignant bone tumor; grade
A
2018
New Proposal to Define the Fascial System
Bruno Bordoni, Fabiola Marelli, Bruno Morabito, Roberto Castagna, Beatrice Sacconi, Paul Mazzucco
In this proposal, the authors suggest a new definition for the fascial system, noting that a universally accepted one does not yet exist. They argue for including the epidermis (the outer layer of skin) based on functio…
fasciaConnective tissuefibroblastMyofascialSkin
A
2018
Therapeutic potentials of superoxide dismutase
H Younus
This narrative review explores the therapeutic potential of superoxide dismutases (SODs), a group of enzymes that serve as a crucial antioxidant defense against oxidative stress in the body. The author discusses the rol…
Oxidative stresssuperoxide dismutasetherapeutic effects