Research.
Every peer-reviewed study on fascia in one place — graded for strength of evidence, summarised in plain language for clinicians, researchers, and curious readers.
We grade studies from A to 1A+++ using the Fascia Research Database rubric — 1A+++ is the strongest.
Researchers behind the studies- B2019
Modeling and simulation of musculoskeletal system of human lower limb based on tensegrity structure
Zhanxi Wang, Chaoran Yang, Kang Feng, Xiansheng QinResearchers created a computer model of the human lower limb's musculoskeletal system using tensegrity principles, which balance tension and compression. Using an established muscle model (the Hill model), they simulate…
Tensegrity structure; lower limb model; motion analysis; gait simulation - C2019
Platelet decoys inhibit thrombosis and prevent metastatic tumor formation in preclinical models
Anne-Laure Papa, Amanda Jiang, Netanel Korin, Michelle B Chen, Erin T Langan, Anna Waterhouse, Emma Nash, Jildaz Carof,…Platelets are crucial for blood clotting but can also contribute to thrombosis and cancer metastasis. In this preclinical study, researchers created modified human platelets, called "platelet decoys," that retained thei…
Plateletplatelet decoystrombosismetastatic tumors - A++2019
8 natural supplements to help fight inflammation
Zawn VillinesInflammation is a natural response to injury or infection, but when it becomes chronic, it can lead to long-term pain and tissue damage. This article reviews several natural supplements that may help the body manage chr…
inflammationomega-3curcumin - A2019
Adhesive capsulitis: MRI correlation with clinical stages and proposal of MRI staging
Amarnath Chellathurai, Komalavalli Subbiah, Atchaya Elangovan,, Sivakumar KannappanThis study investigated whether magnetic resonance imaging (MRI) findings can reflect the clinical stages of adhesive capsulitis, also known as frozen shoulder. Researchers analyzed MRIs from 74 patients, looking for sp…
Adhesive capsulitis; MRI staging; magnetic resonance imaging; frozen shoulder - A2019
Mechanobiology of cells and cell systems, such as organoids
Ece Bayir, Aylin Sendemir, Yannis F MissirlisThis review discusses organoids, which are three-dimensional tissues grown in a lab that self-organize to mimic organ development. While organoids offer great potential for disease modeling and drug development, little…
mechanotransductionmechanobiologyOrganoidMechanoepigeneticsCollective cell behavior - A2019
Age-related changes in leg proprioception: implications for postural control
Mélanie Henry, Stéphane BaudryThis narrative review examines how aging affects proprioception—the body's sense of its own position and movement—and its implications for balance. To maintain an upright stance, the brain relies on signals from recepto…
proprioceptionmuscle spindlesbalanceIa afferentsupright standing - A+2019
Effect of breakfast on weight and energy intake: systematic review and meta-analysis of randomised controlled trials
Katherine Sievert, Sultana Monira Hussain, Matthew J Page, Yuanyuan Wang, Harrison J Hughes, Mary Malek, Flavia M Cicut…This systematic review and meta-analysis examined whether regular breakfast consumption affects body weight and energy intake in adults from high-income countries. The findings suggest that individuals who skipped break…
beakfastweight control - A++2018
Ascorbic acid in cancer treatment: let the phoenix fly
Niraj Shenoy, Edward Creagan, Thomas Witzig, Mark LevineThis review article discusses the renewed interest in Vitamin C (ascorbic acid) as a potential anti-cancer agent. When administered intravenously, Vitamin C can reach much higher concentrations in the body than when tak…
cancerVitamin Cascorbatepharmacokinetics - A++2018
Female hormones: do they influence muscle and tendon protein metabolism?
Mette HansenThis narrative review examines how female sex hormones, particularly estrogen, influence the metabolism of proteins in muscles and tendons. After menopause, declining hormone levels are associated with accelerated muscl…
ACL anterior cruciate ligament; ER oestrogen receptors; ERT oestrogen replacement therapy; HRT hormone replacement therapy; IGF-I insulin-like growth factor-I; OC oral contraceptive; Collagen; Hormone replacement therapy; Muscle strength; Oestrogen; Sarcopenia. - A+++2018
Improvement of Functional Ankle Properties Following Supplementation with Specific Collagen Peptides in Athletes with Chronic Ankle Instability
Patrick Dressler, Dominic Gehring, Denise Zdzieblik, Steffen Oesser, Albert Gollhofer, Daniel KönigThis randomized, placebo-controlled study investigated the effect of specific collagen peptides on athletes with chronic ankle instability (CAI). Fifty athletes received either a daily collagen supplement or a placebo f…
collagennutritionAnkle sprainligaments - A2018
Fractal fluctuations in muscular activity contribute to judgments of length but not heaviness via dynamic touch
Madhur Mangalam, James D Conners, Damian G Kelty-Stephen, Tarkeshwar SinghCOPD (Chronic Obstructive Pulmonary Disease) is a progressive condition that often involves chest pain. This article analyzes the possible causes of this pain, focusing on a less frequently considered source: the fascia…
Biotensegrity · Effortful touch · Fractality · Haptic perception · Multifractality · Muscular effort · Perceptual invariance · Psychophysics - A2018
A New Concept of Biotensegrity Incorporating Liquid Tissues: Blood and Lymph
Bruno Bordoni, Fabiola Marelli, Bruno Morabito, Roberto CastagnaThis conceptual article proposes an update to the biotensegrity model, which traditionally focuses on the solid structures of the fascial system. The authors argue that "liquid tissues" like blood and lymph should also…
fasciaChiropracticManual TherapyMyofascialOsteopathic