Research.
Every peer-reviewed study on fascia in one place — graded for strength of evidence, summarised in plain language for clinicians, researchers, and curious readers.
We grade studies from A to 1A+++ using the Fascia Research Database rubric — 1A+++ is the strongest.
Researchers behind the studies- A2019
Cranial osteopathy: Obscurantism and Enlightenment
Bruno Bordoni, Bruno Morabito, Marta SimonelliIn this reflective article, the authors discuss the controversial aspects of cranial osteopathy. They address common objections, such as the idea that the cranial bones are immobile in adults and that an operator's hand…
fasciaOsteopathicquantum physicsneurophysiologycranio - A2019
Lymphatic pump manipulation in patients with chronic obstructive pulmonary disease
Bruno BordoniThis narrative review examines the use of lymphatic pump manipulation for patients with chronic obstructive pulmonary disease (COPD). COPD is characterized by persistent inflammation, and lymphatic techniques aim to red…
inflammationfasciaOsteopathicCOPDlymphatic pump - A2019
Tissue Regeneration from Mechanical Stretching of Cell–Cell Adhesion
Amir Monemian Esfahani, Jordan Rosenbohm, Keerthana Reddy, Xiaowei Jin, Tasneem Bouzid, Brandon Riehl, Eunju Kim, Jung…This narrative review explores how mechanical stretching can stimulate tissue regeneration and wound healing. Researchers have long known that cells respond to mechanical forces, but much of the focus has been on the co…
wound healingmechanotransductioncell–cell adhesionmechanical stretchingtissue regeneration - A2019
Imaging of ultraweak photon emission for evaluating the oxidative stress of human skin
Katsuhiko Tsuchidaa, Torai Iwasab, Masaki KobayashiThis study explored a method for visualizing oxidative stress in human skin by imaging ultraweak photon emission (UPE), also known as biophotons. Researchers found that exposing skin to UV radiation increased the intens…
BiophotonOxidationImagingNon-invasiveUltraviolet - A2019
Where is your head? Perception of relative position of the head on a wielded object
Jeffrey B Wagman, Takahiro HiguchiThis study explored how we perceive our body's position relative to an object we are holding or balancing. Researchers specifically tested this by having participants "wield" an object with their head, a body part not t…
Haptics . Perception and action . Touch - A2019
Existence and features of the myodural bridge in Gallus domesticus: indication of its important physiological function
Ya-Ru Dou, Nan Zheng, Jing Gong, Wei Tang, Chukwuemeka Samuel Okoye, Ying Zhang, Yu-Xiao Chen, Yu Zhang, Shi-Yi Pi, Lia…In this anatomical animal study, researchers investigated the existence of the myodural bridge (MDB) in chickens. The MDB is a dense connective tissue that links muscles in the upper neck to the spinal dura mater. The i…
Myodural Bridgecerebrospinal fluid circulationCollagen fiberGallus domesticus - B2019
Extracellular matrix composition of connective tissues: a systematic review and meta-analysis
Turney J McKee, George Perlman, Martin Morris, Svetlana V KomarovaThis systematic review and meta-analysis compiled data to quantify the protein composition of the extracellular matrix (ECM) in various human connective tissues. Researchers analyzed data from studies on bone, adipose t…
extracellular matrixmatrix remodelingcollagen content - A++2019
Local Vibration Stimuli Induce Mechanical Stress-Induced Factors and Facilitate Recovery From Immobilization-Induced Oxidative Myofiber Atrophy in Rats
Fusako Usuki, Masatake Fujimura, Atsushi Nakamura, Jiro Nakano, Minoru Okita, Itsuro HiguchiThis study on rats investigated whether local vibration could help muscles recover after being immobilized. Researchers put a cast on one hindlimb of the rats for a week to induce muscle atrophy. After removing the cast…
YAP1; local vibration; mechano-growth factor; mechanotransduction; oxidative myofiber atrophy; satellite cell; therapeutics. - A2019
Biotensegrity or Fascintegrity
Bruno Bordoni, Matthew A Varacallo, Bruno Morabito, Marta SimonelliIn this theoretical review, the authors question the popular "biotensegrity" model for describing the body's mechanics. They argue the model is incomplete because it fails to account for crucial factors like bodily flui…
fasciaMyofascialOsteopathicphysiotherapyskeletal muscle - A2019
3D volumetric MR arthrographic assessment of shoulder joint capacity in patients with primary adhesive capsulitis
Hayri Ogul, Nurmuhammet Tas, Kutsi Tuncer, Gokhan Polat, Yasemin Ogul, Berhan Pirimoglu, Mecit KantarciThis study used 3D MR arthrography to measure and compare shoulder joint volume in patients with primary adhesive capsulitis (frozen shoulder) against a healthy control group. Researchers found that the patient group ha…
frozen shoulderAdhesive capsulitisMR arthrography - A2019
Glut-1 explains the evolutionary advantage of the loss of endogenous vitamin C-synthesis
Tabea C Hornung, Hans-Konrad BiesalskiUnlike many animals, humans cannot produce their own vitamin C. This study explores a potential evolutionary advantage of this loss. Researchers compared red blood cells from humans and pigs (who can make vitamin C) and…
glucose transporter; vitamin C; gulono-lactone-oxidase; vitamin C recycling - A2019
The Primo Vascular System as a Possible Exosomal Route Across the Body: Implications for Tumor Proliferation and Metastasis
Chiara GhironThis literature review proposes a possible link between the primo vascular system (PVS)—a network associated with Traditional Chinese Medicine meridians—and the way cancer spreads. The theory is that exosomes, tiny vesi…
cancer microenvironment; exosomes; hyaluronic acid; primo vascular system; tumor metastasis.
