Research.
Every peer-reviewed study on fascia in one place — graded for strength of evidence, summarised in plain language for clinicians, researchers, and curious readers.
We grade studies from A to 1A+++ using the Fascia Research Database rubric — 1A+++ is the strongest.
Researchers behind the studies- A2019
Anterior capsular abnormality: another important MRI finding for the diagnosis of adhesive capsulitis of the shoulder
Jina Park, Yoon-Hee Choi, Jee Won Chai, Seung Woo Cha, Joo Hee Lim, Chris Hyunchul Jo, Dong Hyun KimThis retrospective study investigated whether abnormalities in the shoulder's anterior joint capsule, seen on MRI scans, can help diagnose adhesive capsulitis (frozen shoulder). Researchers compared MRIs from 29 patient…
Anterior capsular abnormalityAdhesive capsulitis of shoulderAnterior capsular thicknessAnterior capsular abnormal hyperintensity - A2019
Evaluation of the Structure of Myodural Bridges in an Equine Model of Ehlers-Danlos Syndromes
Abigail McElroy, Ann Rashmir, Jane Manfredi, Dodd Sledge, Elizabeth Carr, Edward Stopa, Petra KlingeThis animal study investigated myodural bridges—connective tissue links between small neck muscles and the spinal cord's outer covering (dura mater)—in horses. Researchers compared horses with a genetic connective tissu…
Myodural BridgeEhlers-danlos syndromes - A2019
Lymphatic pump manipulation in patients with chronic obstructive pulmonary disease
Bruno BordoniThis narrative review examines the use of lymphatic pump manipulation for patients with chronic obstructive pulmonary disease (COPD). COPD is characterized by persistent inflammation, and lymphatic techniques aim to red…
inflammationfasciaOsteopathicCOPDlymphatic pump - A2019
Existence and features of the myodural bridge in Gallus domesticus: indication of its important physiological function
Ya-Ru Dou, Nan Zheng, Jing Gong, Wei Tang, Chukwuemeka Samuel Okoye, Ying Zhang, Yu-Xiao Chen, Yu Zhang, Shi-Yi Pi, Lia…In this anatomical animal study, researchers investigated the existence of the myodural bridge (MDB) in chickens. The MDB is a dense connective tissue that links muscles in the upper neck to the spinal dura mater. The i…
Myodural Bridgecerebrospinal fluid circulationCollagen fiberGallus domesticus - B2019
Extracellular matrix composition of connective tissues: a systematic review and meta-analysis
Turney J McKee, George Perlman, Martin Morris, Svetlana V KomarovaThis systematic review and meta-analysis compiled data to quantify the protein composition of the extracellular matrix (ECM) in various human connective tissues. Researchers analyzed data from studies on bone, adipose t…
extracellular matrixmatrix remodelingcollagen content - A+++2019
Drinking hydrogen water enhances endurance and relieves psychometric fatigue: a randomized, double-blind, placebo-controlled study
Toshio Mikami, Kohei Tano, Hosung Lee, Hyowon Lee, Jonghyuk Park, Fumiaki Ohta, Tyler W LeBaron, Shigeo OhtaThis randomized, double-blind, placebo-controlled study investigated the effects of drinking hydrogen-infused water (H2 water) before exercise. Across two experiments involving both untrained and trained participants on…
exercise; fatigue; hydrogen; hydrogen water - A++2019
Development of a biotensegrity focused therapy for the treatment of pelvic organ prolapse: A retrospective case series
Anna Crowle, Clare HarleyThis retrospective case series explores a new biotensegrity-focused therapy for pelvic organ prolapse (POP). Challenging the common view that POP is caused by weak tissue, this approach hypothesizes that the condition i…
Myofascial releasebiotensegrityPelvic organ prolapsePelvic tension - A2019
Glut-1 explains the evolutionary advantage of the loss of endogenous vitamin C-synthesis
Tabea C Hornung, Hans-Konrad BiesalskiUnlike many animals, humans cannot produce their own vitamin C. This study explores a potential evolutionary advantage of this loss. Researchers compared red blood cells from humans and pigs (who can make vitamin C) and…
glucose transporter; vitamin C; gulono-lactone-oxidase; vitamin C recycling - A2019
Biophysics of Cell-Substrate Interactions Under Shear
Neha Paddillaya, Ashish Mishra, Paturu Kondaiah, Pramod Pullarkat, Gautam I Menon, Namrata GundiahIn this review article, the authors examine how cells adhere to surfaces and respond to mechanical forces. Cells use complex structures called focal adhesions to sense and react to their environment, including forces fr…
mechanotransductionfocal adhesionsstress fibersshear stress and devicesbiophysical models - A++2019
Vitamin C Inhibits Triple-Negative Breast Cancer Metastasis by Affecting the Expression of YAP1 and Synaptopodin 2
Liping Gan, Vladimir Camarena, Sushmita Mustafi, Gaofeng WangIn this study using cell cultures and animal models, researchers investigated how vitamin C might inhibit the spread of triple-negative breast cancer (TNBC). They found that vitamin C, at concentrations achievable throu…
F-actin; HIF-1α; YAP1; hippo pathway; lamellipodia; metastasis; synaptopodin 2; triple-negative breast cancer; vitamin C. - A+2019
Anti-Inflammatory Diets and Fatigue
Ulrike Hass, Catrin Herpich, Kristina NormanThis narrative review explores the link between pro-inflammatory status and chronic disease-related fatigue in conditions such as cancer, fibromyalgia, and chronic fatigue syndrome. While evidence for individual nutrien…
anti-inflammatory nutrition; cancer; chronic fatigue; cytokines; fatigue reduction diet; inflammation; myalgic encephalomyelitis; omega-3 fatty acids; polyphenols; probiotics. - A+2019
Collagen changes in pelvic support tissues in women with pelvic organ prolapse
Runqi Gong, Zhijun XiaThis narrative review summarizes research on how changes in collagen are linked to pelvic organ prolapse in women. Collagen is a critical component of the pelvic floor, providing essential supportive functions. Studies…
extracellular matrixcollagenBiomechanicsPelvic organ prolapseSignaling pathways