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Research.

Every peer-reviewed study on fascia in one place — graded for strength of evidence, summarised in plain language for clinicians, researchers, and curious readers.

We grade studies from A to 1A+++ using the Fascia Research Database rubric — 1A+++ is the strongest.

Researchers behind the studies
2,806
studies
602
top-graded
2,783
with plain-language summary
Showing 325–336 of 736 studies · page 28/62Since 2015
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A+++2019

Vitamin C and Neutrophil Function: Findings from Randomized Controlled Trials

Mikee Liugan, Anitra C Carr

This systematic review examined how vitamin C supplementation affects neutrophils, a key type of immune cell. Researchers analyzed 16 randomized controlled trials that measured neutrophil functions like their ability to…

vitamin C; ascorbic acid; neutrophils; polymorphonuclear leukocytes; migration; chemotaxis; apoptosis; phagocytosis; oxidative burst; systematic review
B2019

Modeling and simulation of musculoskeletal system of human lower limb based on tensegrity structure

Zhanxi Wang, Chaoran Yang, Kang Feng, Xiansheng Qin

Researchers created a computer model of the human lower limb's musculoskeletal system using tensegrity principles, which balance tension and compression. Using an established muscle model (the Hill model), they simulate…

Tensegrity structure; lower limb model; motion analysis; gait simulation
C2019

Platelet decoys inhibit thrombosis and prevent metastatic tumor formation in preclinical models

Anne-Laure Papa, Amanda Jiang, Netanel Korin, Michelle B Chen, Erin T Langan, Anna Waterhouse, Emma Nash, Jildaz Carof,…

Platelets are crucial for blood clotting but can also contribute to thrombosis and cancer metastasis. In this preclinical study, researchers created modified human platelets, called "platelet decoys," that retained thei…

Plateletplatelet decoystrombosis
A2019

Fascia thickness, aging and flexibility: is there an association?

Jan Wilke, Veronica Macchi, Raffaele De Caro, Carla Stecco

This study investigated how deep fascia thickness relates to age and flexibility in healthy women. Researchers compared a group of young women with a group of older women, using ultrasound to measure fascia thickness an…

connective tissue; hyaluronic acid; stiffness; myofascial; aging
A++2019

Mitochondrial superoxide anions induced by exogenous oxidative stress determine tumor cell fate: an individual cell-based study

Hui PAN, Bao-hui WANG, Zhou-bin LI, Xing-guo GONG, Yong QIN, Yan JIANG, Wei-li HAN

In this cell-based study, researchers investigated how external oxidative stress affects individual lung cancer cells. They found that applying a stressor like hydrogen peroxide caused a rapid increase in reactive oxyge…

Individual cell; Superoxide anion; Reactive oxygen species (ROS) dynamics; Intrinsic apoptotic pathway; Ca2+ signaling
A+2019

Role of a natural integrator based on lipoic acid, palmitoiletanolamide and myrrh in the treatment of chronic pelvic pain and endometriosis

Vincenzo De Leo, Angelo Cagnacci, Valentina Cappelli, Anna Biasioli, Deborah Leonardi, Renato Seracchioli

This study investigated a nutritional supplement for endometriosis-related pain. Sixty women with ovarian endometriosis and chronic pelvic pain took a supplement containing alpha-lipoic acid, palmitoylethanolamide (PEA)…

nutraceuticalendometriosispelvic pain
A2019

High-dose vitamin C suppresses the invasion and metastasis of breast cancer cells via inhibiting epithelial-mesenchymal transition

Ling-Hui Zeng, Qing-Mei Wang, Lin-Yi Feng, Yu-Dun Ke, Qian-Zi Xu, An-Yi Wei, Chong Zhang, Rong-Biao Ying

This study on breast cancer cells in the lab and in mice explored how different doses of vitamin C affect cancer cell behavior. Researchers found that low and medium doses of vitamin C seemed to encourage cancer cells t…

Breast cancermetastasisTGF-β1
A++2019

Fascial organisation of motor synergies: a hypothesis

Alessandro Garofolini, Daris Svanera

This hypothesis paper explores how fascia helps organize movement through what are known as motor synergies. It suggests that instead of the brain controlling every muscle individually, the fascial system acts as a phys…

Motor control; degrees of freedom; movement coordination; muscle spindle; myofascial continuity.
A2019

The neural basis of the senses of effort, force and heaviness

Uwe Proske, Trevor Allen

This narrative review explores how we sense effort, force, and heaviness during muscle contraction. Traditionally, these sensations were thought to originate in the brain from copies of motor commands. However, new evid…

Force sense · Proprioception · Muscle spindle · Tendon organ · Motor command · Efference copy · Vibration
B2019

The Fascial Connections of the Pectineal Ligament

Hanno Steinke, Dina Wiersbicki, Anna Völker, Philipp Pieroh, Charlotte Kulow, Benjamin Wolf, Georg Osterhoff

This anatomical study investigated the detailed fascial connections of the pectineal ligament using dissection and analysis of ten human specimens. Researchers found the ligament acts as a connective tissue junction bet…

tendinous arch of levator aniiliopubic tract; obturator fascia; pectineal ligamentpectineal fascia; Waldeyers’ fascia; Gerota’s fascia; Zuckerkandl’s fascia; Toldt’s fascia
A2019

Effects of foam rolling on performance and recovery: A systematic review of the literature to guide practitioners on the use of foam rolling

Sharief Hendricks, Hayd'n Hill, Steve den Hollander, Wayne Lombard, Romy Parker

This systematic review analyzed 49 studies to understand how foam rolling affects athletic performance and recovery. The authors found evidence that foam rolling can decrease muscle stiffness and improve range of motion…

FlexibilityFoam rollingPerformance
C2019

Cell Biology: Function Guides Form of Auditory Sensory Cells

Jamis McGrath, Benjamin J Perrin

This study describes how the sensory cells in our ears get their specific shape. These cells have bundles of tiny hair-like structures called stereocilia, arranged like a staircase in rows of decreasing height. The proc…

mechanotransductionauditory sensory cells