Skip to content

Research.

Every peer-reviewed study on fascia in one place — graded for strength of evidence, summarised in plain language for clinicians, researchers, and curious readers.

We grade studies from A to 1A+++ using the Fascia Research Database rubric — 1A+++ is the strongest.

Researchers behind the studies
2,806
studies
602
top-graded
2,783
with plain-language summary
Showing 253–264 of 1,131 studies · page 22/95
A+++2019

Daily oral dosing of vitamin D3 using 5000 TO 50,000 international units a day in long-term hospitalized patients: Insights from a seven year experience

Patrick J McCullough, Douglas S Lehrer, Je!rey Amend

This observational study followed long-term hospitalized patients over seven years to evaluate the safety of high daily doses of vitamin D3. Patients received supplements ranging from 5,000 to 50,000 international units…

vitamin DIntact parathyroid hormoneLong-term supplementation
A2019

Hyaluronan/collagen hydrogels containing sulfated hyaluronan improve wound healing by sustained release of heparin-binding EGF-like growth factor

Stephan Thönes, Sandra Rother, Tom Wippold, Joanna Blaszkiewicz, Kanagasabai Balamurugan, Stephanie Moeller, Gloria Rui…

This study investigated a new type of hydrogel designed to improve wound healing. Researchers combined collagen and hyaluronan (HA), a natural component of connective tissue, with a growth factor that stimulates skin ce…

Biomimetic material; Extracellular matrix (ECM); Fibroblasts; Heparin-binding epidermal growth factor-like growth factor (HB-EGF); Hyaluronan; Hydrogel; Sulfated hyaluronan; Surface plasmon resonance; Wound healing.
A+++2019

Tentorium Cerebelli: the Bridge Between the Central and Peripheral Nervous System, Part 2

Bruno Bordoni, Marta Simonelli, Maria Marcella Lagana

This article, the second in a series, describes the tentorium cerebelli—a meningeal structure related to the skull, nervous system, and cervical spine. The authors discuss its complex relationships, including its neurol…

fasciapaincranio
1A+2019

The fascial breath

Bruno Bordoni, Marta Simonelli, Bruno Morabito

This narrative review proposes a new way of understanding the diaphragm muscle, moving beyond a purely mechanical view. The authors argue that the diaphragm is not just covered by fascia but is fundamentally a fascial t…

fasciaMyofascialOsteopathic
A++2019

Plasma Amino Acid Concentrations After the Ingestion of Dairy and Collagen Proteins, in Healthy Active Males

Rebekah D Alcock, Gregory C Shaw, Nicolin Tee, Louise M Burke

This study investigated how blood amino acid levels changed in healthy, active men after they consumed either collagen or dairy proteins. Researchers found that the different protein sources led to distinct amino acid p…

Connective tissuetendonligament
A+++2019

The Endocannabinoid/Endovanilloid System in Bone: From Osteoporosis to Osteosarcoma

Francesca Rossi, Chiara Tortora, Francesca Punzo, Giulia Bellini, Maura Argenziano, Alessandra Di Paola, Marco Torella,…

Bone is a dynamic tissue, whose homeostasis is maintained by a fine balance between osteoclast (OC) and osteoblast (OB) activity. The endocannabinoid/endovanilloid (EC/EV) system's receptors are the cannabinoid receptor…

CB1; CB2; TRPV1; bone; osteoblasts; osteoclasts; osteoporosis; osteosarcoma
A+++2019

New Insights of Uterine Leiomyoma Pathogenesis: Endocannabinoid System

Thangesweran Ayakannu, Anthony H Taylor, Timothy H Marczylo, Justin C Konje

This study investigated the role of the endocannabinoid system in the development of uterine leiomyomas, commonly known as fibroids. Researchers analyzed tissue samples and found that the expression of specific receptor…

CannabinoidsCannabinoid receptorsuterine myom
A++2019

Development of a biotensegrity focused therapy for the treatment of pelvic organ prolapse: A retrospective case series

Anna Crowle, Clare Harley

This retrospective case series explores a new biotensegrity-focused therapy for pelvic organ prolapse (POP). Challenging the common view that POP is caused by weak tissue, this approach hypothesizes that the condition i…

Myofascial releasebiotensegrityPelvic organ prolapse
A2019

The diaphragm muscle manual evaluation scale

Bruno Bordoni, Bruno Morabito

This technical report describes a new method for manually assessing the diaphragm's function, called the Manual Evaluation Diaphragm (MED) scale. The scale is designed to generate a value for the respiratory muscle's mo…

fasciaMyofascialdiaphragm
A2019

Quantifying muscle glycosaminoglycan levels in patients with post-stroke muscle stiffness using T1p MRI

Rajiv G Menon, Preeti Raghavan, Ravinder R Regatte

This study is the first to quantify the amount of hyaluronan, a key component for gliding movements within fascia. Researchers measured hyaluronan in tissue samples from various human anatomical sites and found that the…

hyaluronanStrokestiffness
B2019

Modeling and simulation of musculoskeletal system of human lower limb based on tensegrity structure

Zhanxi Wang, Chaoran Yang, Kang Feng, Xiansheng Qin

Researchers created a computer model of the human lower limb's musculoskeletal system using tensegrity principles, which balance tension and compression. Using an established muscle model (the Hill model), they simulate…

Tensegrity structure; lower limb model; motion analysis; gait simulation
B2019

Photo-crosslinked gelatin-hyaluronic acid methacrylate hydrogel-committed nucleus pulposus-like differentiation of adipose stromal cells for intervertebral disc repair

Pengfei Chen, Lei Ning, Pengcheng Qiu, Jian Mo, Sheng Mei, Chen Xia, Jianfeng Zhang, Xianfeng Lin, Shunwu Fan

This animal study on rats investigated a new strategy for repairing degenerated intervertebral discs using stem cells. Researchers combined adipose-derived stromal cells (ASCs) with a special light-activated hydrogel ma…

IntegrinsmicroenvironmentHydrogel