Skip to content
The Fascia Guide
SVEN

Research.

Every peer-reviewed study on fascia in one place — graded for strength of evidence, summarised in plain language for clinicians, researchers, and curious readers.

We grade studies from A to 1A+++ using the Fascia Research Database rubric — 1A+++ is the strongest.

Researchers behind the studies
2,806
studies
602
top-graded
2,783
with plain-language summary
TopicAllfascia233extracellular matrix51hyaluronan46inflammation40Connective tissue39mechanotransduction36collagen32Vitamin C31Manual Therapy30acupuncture24
GradeAll1A+++41A++21A+42A++++1A+++317A++236A+84A435
YearAll yearsSince 2020Since 2015Since 2010With summary
SortBy gradeBy yearA–Z
View
ListGrid
Showing 253–264 of 736 studies · page 22/62Since 2015
Clear
  1. A+++
    2019

    Vitamin C administration in the critically ill: a summary of recent meta-analyses

    Anitra C Carr

    This 2019 publication is a summary of recent meta-analyses on the topic of vitamin C administration for critically ill patients. As the full text has not yet been reviewed, a detailed summary of its findings is not avai…

    Vitamin CAscorbic acidsepsis
  2. A+++
    2019

    Cannabis sativa L. extract and cannabidiol inhibit in vitro mediators of skin inflammation and wound injury

    Enrico Sangiovanni, Marco Fumagalli, Barbara Pacchetti, Stefano Piazza, Andrea Magnavacca, Saba Khalilpour, Gloria Melz…

    This in vitro study investigated how Cannabis sativa extract and its component cannabidiol (CBD) affect inflammation in human skin cells. Researchers found that both the extract and pure CBD reduced the release of sever…

    Cannabis sativa L.; cannabidiol; fibroblasts; keratinocytes; skin inflammation; wound injury.
  3. 1A+
    2019

    The Other Side of the Fascia: The SmoothMuscle Part 1

    Bruno Bordoni, Marta Simonelli, Bruno Morabito

    This theoretical article challenges the standard definition of fascia. Traditionally, fascia is considered connective tissue originating from two embryonic layers, the mesoderm and ectoderm. The authors propose expandin…

    fasciaMyofascialOsteopathicsmooth musclemesoderm
  4. A
    2019

    Chronic low back pain influences trunk neuromuscular control during unstable sitting among persons with lower-limb loss

    Courtney M Butowicz, Julian C Acasio, Silfies Sheri P, Maury A Nussbaum, Brad D Hendershot

    People with lower-limb loss are at a higher risk for chronic low back pain. This study investigated whether trunk postural control differs between those with and without pain in this population. Researchers had men with…

    low back painBiomechanicsPostural controlAmputation
  5. A
    2019

    Lipedema: A Call to Action!

    Giacomo Buso, Michele Depairon, Didier Tomson, Wassim Raffoul, Roberto Vettor, Lucia Mazzolai

    This narrative review summarizes the current understanding of lipedema, a chronic and progressive disease primarily affecting women. It is characterized by a painful, abnormal distribution of fat in the limbs, which oft…

    lymphedemalipedema; obesity
  6. A
    2019

    Lymphatic pump manipulation in patients with chronic obstructive pulmonary disease

    Bruno Bordoni

    This narrative review examines the use of lymphatic pump manipulation for patients with chronic obstructive pulmonary disease (COPD). COPD is characterized by persistent inflammation, and lymphatic techniques aim to red…

    inflammationfasciaOsteopathicCOPDlymphatic pump
  7. A+++
    2019

    Cannabidiol differentially regulates basal and LPS-induced inflammatory responses in macrophages, lung epithelial cells, and fibroblasts

    Thivanka Muthumalage, Irfan Rahman

    This laboratory study investigated how cannabidiol (CBD) influences inflammatory responses in lung epithelial cells, fibroblasts, and immune cells. The researchers found that CBD can reduce inflammation triggered by ext…

    CBD; E-cigarette; E-liquid; Lung; Marijuana; Vaping
  8. A++
    2019

    Fascial Entrapment Neuropathy

    ANTONIO STECCO, CARMELO PIRRI, CARLA STECCO

    This narrative review explores how fascia can contribute to nerve entrapment syndromes, which cause pain, sensory abnormalities, and weakness. The authors describe how nerves are surrounded by a microenvironment of conn…

    nerve; nerve entrapment; fascia; Parsonage-Turner
  9. A
    2019

    Cranial osteopathy: Obscurantism and Enlightenment

    Bruno Bordoni, Bruno Morabito, Marta Simonelli

    In this reflective article, the authors discuss the controversial aspects of cranial osteopathy. They address common objections, such as the idea that the cranial bones are immobile in adults and that an operator's hand…

    fasciaOsteopathicquantum physicsneurophysiologycranio
  10. 1A+
    2019

    The Other Side of the Fascia: Visceral Fascia, Part 2

    Bruno Bordoni, Marta Simonelli, Bruno Morabito

    This editorial, part two of a series, argues for including certain internal organs (viscera) within the definition of fascia. From an osteopathic perspective, the authors suggest that understanding these organs as fasci…

    fasciaMyofascialOsteopathicsmooth musclemesoderm
  11. A+
    2019

    Anti-Inflammatory Diets and Fatigue

    Ulrike Hass, Catrin Herpich, Kristina Norman

    This narrative review explores the link between pro-inflammatory status and chronic disease-related fatigue in conditions such as cancer, fibromyalgia, and chronic fatigue syndrome. While evidence for individual nutrien…

    anti-inflammatory nutrition; cancer; chronic fatigue; cytokines; fatigue reduction diet; inflammation; myalgic encephalomyelitis; omega-3 fatty acids; polyphenols; probiotics.
  12. C
    2019

    Involvement of Acid-Sensing Ion Channel 1b in the Development of Acid-Induced Chronic Muscle Pain

    Chu-Ting Chang, Sitt Wai Fong, [...], Chih-Cheng Chen

    In this animal study, researchers investigated the role of a specific ion channel, called ASIC1b, in the development of chronic muscle pain. They created a fibromyalgia-like condition by injecting acid into the leg musc…

    FibromyalgiapainASICASIC1bASIC3