Research.
Every peer-reviewed study on fascia in one place — graded for strength of evidence, summarised in plain language for clinicians, researchers, and curious readers.
We grade studies from A to 1A+++ using the Fascia Research Database rubric — 1A+++ is the strongest.
Researchers behind the studiesRole of vitamin K 2 in bone metabolism: a point of view and a short reappraisal of the literature
This narrative review examines the role of Vitamin K2 in bone metabolism and its contribution to maintaining skeletal integrity. Vitamin K2 is essential for activating osteocalcin, a key protein that binds calcium to th…
Is the extent of obstetric anal sphincter injury correlated with the severity of fecal incontinence in the long term?
This retrospective study investigated the relationship between the extent of obstetric anal sphincter injury and the severity of long-term fecal incontinence (FI). Researchers analyzed data from 250 women with a mean ag…
The potential of cannabidiol in the COVID-19 pandemic
This scientific hypothesis explores the potential of cannabidiol (CBD) as a supportive treatment during the COVID-19 pandemic. The authors suggest that CBD may down-regulate the receptors the virus uses for cellular ent…
Cannabis and cannabidiol (CBD) for the treatment of fibromyalgia
This narrative review examines the use of cannabis and cannabidiol (CBD) for treating fibromyalgia, a complex condition that often responds poorly to standard therapies. The authors note that while high-quality randomiz…
Sustained Cerebrovascular and Cognitive Benefits of Resveratrol in Postmenopausal Women
This randomized controlled trial investigated how daily resveratrol supplementation affects brain health in postmenopausal women over a 12-month period. Participants took either 75 mg of trans-resveratrol twice daily or…
Ageing of the diaphragm muscle
This narrative review explores how the diaphragm, our main breathing muscle, is affected by aging. Like other muscles, the diaphragm can weaken and lose mass over time, a condition known as sarcopenia. This age-related…
Mechanical sensing protein PIEZO1 regulates bone homeostasis via osteoblast-osteoclast crosstalk
This study using mouse models investigates how the protein PIEZO1 acts as a mechanical sensor in the skeleton to regulate bone mass. Researchers found that a deficiency of PIEZO1 in bone-forming cells (osteoblasts) lead…
Muscle Cramps
Muscle cramps are involuntary, painful, and localized contractions of a muscle or muscle fibers, often felt as a palpable knot. While common in sports, their exact cause is not fully understood and likely depends on var…
Fasting-mimicking diet plus chemotherapy in breast cancer treatment
This clinical trial investigated whether a fasting-mimicking diet (FMD) combined with chemotherapy could improve outcomes for breast cancer patients. The overall results were negative, meaning the study did not find a s…
Sympathetic activation: a potential link between comorbidities and COVID-19
In this perspective article, researchers propose a potential link between common comorbidities and severe COVID-19 outcomes. Conditions like heart disease, hypertension, and diabetes, which are risk factors for severe C…
Diet as a Modulator of Intestinal Microbiota in Rheumatoid Arthritis
This narrative review explores how dietary patterns can influence the gut microbiota in individuals with rheumatoid arthritis (RA). Research indicates that RA patients often exhibit significant differences in their inte…
Gut Microbiota and Cardiovascular Disease
This review explores how the gut microbiota influences cardiovascular health through the production of specific metabolic byproducts. Research suggests that the link is not merely associative; certain bacterial metaboli…