Research.
Every peer-reviewed study on fascia in one place — graded for strength of evidence, summarised in plain language for clinicians, researchers, and curious readers.
We grade studies from A to 1A+++ using the Fascia Research Database rubric — 1A+++ is the strongest.
Researchers behind the studiesPrevention and treatment of COVID-19 infection by earthing
This observational study investigated the effects of 'earthing'—direct physical contact with the ground—in 59 people with COVID-19. Participants engaged in earthing for 15 minutes to 3 hours daily. The author reported t…
Long-term resveratrol supplementation improves pain perception, menopausal symptoms, and overall well-being in postmenopausal women: findings from a 24-month randomized, controlled, crossover trial
This 24-month randomized controlled crossover trial investigated the effects of daily resveratrol supplementation in 125 postmenopausal women. The findings suggest that taking 75 mg of resveratrol twice daily may reduce…
Manipulation of the Fascial System Applied During Acute Inflammation of the Connective Tissue of the Thoracolumbar Region Affects Transforming Growth Factor-β1 and Interleukin-4 Levels: Experimental Study in Mice
This animal study investigated the effects of manual fascial manipulation on acute inflammation in the connective tissue of mice's lower backs. Researchers induced inflammation and then applied a specific manipulation p…
Low-frequency mechanical vibration induces apoptosis of A431 epidermoid carcinoma cells
Researchers are exploring mechanical vibration as a potential cancer therapy that avoids harming healthy cells. In this lab study, a brief, low-frequency vibration was applied to a line of human skin cancer cells (A431)…
Calf stretching and plantar fascia-specific stretching for plantar fasciitis: A systematic review and meta-analysis
This systematic review and meta-analysis looked at eight studies to compare two common stretching techniques for plantar fasciitis: calf stretching and plantar fascia-specific stretching. The authors analyzed the data t…
Day of peak pain reduction by a single session of dry needling in the upper trapezius myofascial trigger points: A 14 daily follow-up study
This study tracked daily pain in people with upper trapezius trigger points following a single dry needling session. Participants received one treatment combined with self-stretching exercises and reported their pain fo…
Iliopsoas muscle thickness and pelvic alignment in pronated and normal foot postures
This study investigated whether chronic foot hyperpronation is linked to changes in pelvic alignment and iliopsoas muscle thickness. Researchers compared a group of women with pronated feet to a group with normal foot p…
Morphological and immunophenotypic characterization of perivascular interstitial cells in human glioma: Telocytes, pericytes, and mixed immunophenotypes
Researchers investigated two types of cells, telocytes and pericytes, found around blood vessels in brain tumors. The study found that the number of telocytes was ten times higher in the more aggressive glioblastoma tum…
Bicarbonate use and mortality outcome among critically ill patients with metabolic acidosis: A meta analysis
This meta-analysis investigated whether treating critically ill patients with sodium bicarbonate for metabolic acidosis, a condition of excess acid in the blood, affects mortality. The use of bicarbonate in intensive ca…
The relaxin family peptide receptor 1 (RXFP1): An emerging player in human health and disease
This review article explores the relaxin hormone and its receptor, RXFP1, a signaling pathway known for its ability to soften ligaments and connective tissue. While relaxin shows potent antifibrotic potential in laborat…
Narrative review of the epidemiology, diagnosis and pathophysiology of pelvic organ prolapse
This narrative review examines the epidemiology and causes of pelvic organ prolapse (POP), a condition affecting many women's quality of life. The authors highlight a discrepancy in prevalence rates, noting that while a…
Cannabinoids in Medicine: Cancer, Immunity, and Microbial Diseases
This narrative review explores how cannabinoids, including those from plants and those produced naturally by the body, influence health through the endocannabinoid system. The authors describe how these compounds intera…