Skip to content

Research.

Every peer-reviewed study on fascia in one place — graded for strength of evidence, summarised in plain language for clinicians, researchers, and curious readers.

We grade studies from A to 1A+++ using the Fascia Research Database rubric — 1A+++ is the strongest.

Researchers behind the studies
2,806
studies
602
top-graded
2,783
with plain-language summary
Showing 157–168 of 181 studies · page 14/16fasciaSince 2010
Clear
  1. A
    2011

    Hyaluronan: From Extracellular Glue to Pericellular Cue

    B P Toole

    Hyaluronan is traditionally seen as a biological 'goo' that lubricates joints and holds connective tissues together. This review describes how hyaluronan also functions as an important signaling molecule, or cue, in the…

    hyaluronanfasciasignal transductioncancer
  2. A
    2011

    Elevated [11C]-D-Deprenyl Uptake in Chronic Whiplash Associated Disorder Suggests Persistent Musculoskeletal Inflammation

    Clas Linnman, Lieuwe Appel, Mats Fredrikson, Torsten Gordh, Anne Söderlund, Bengt Långström, Henry Engler

    Diagnosing chronic whiplash-associated disorder (WAD) is often difficult, as standard structural imaging methods seldom show clear signs of injury. This study used Positron Emission Tomography (PET) with a tracer molecu…

    inflammationfasciaWhiplash
  3. A
    2011

    Dynamic fascial release and the role of mechanical/vibrational assist devices in manual therapies

    Zachary Comeaux

    This review article explores the use of mechanical vibration devices in manual therapy. The author examines several such tools, including percussion vibrators, vibrational platforms, and deep tissue oscillation. The art…

    fasciaConnective tissuevibrationpercussion vibrationtonic vibratory reflex
  4. A
    2011

    Anatomical Connection Between the Rectus Capitis Posterior Major and the Dura Mater

    Frank Scali, Eric S Marsili, Matthew E Pontell

    In this anatomical study, researchers dissected 13 cadavers to investigate a connection between a deep neck muscle and the dura mater, the protective covering of the spinal cord. In 11 of the 13 specimens, they found a…

    fasciacervical spineposterior atlantoaxial interspacerectus capitis posterior majorspinal dura
  5. B
    2011

    Fascia redefined: anatomical features and technical relevance in fascial flap surgery

    Carla Stecco, Cesare Tiengo, Antonio Stecco, Andrea Porzionato, Veronica Macchi, Robert Stern, Raffaele De Caro

    Fascia has traditionally been seen as a passive wrapping, but this review redefines it as a dynamic tissue with its own complex blood supply and innervation. The authors detail the specific characteristics of different…

    hyaluronanfasciaConnective tissueaponeurosisFlaps
  6. A
    2011

    Sensory Innervation of the Thoracolumbar Fascia in Rats and Humans

    J Tesarz, U Hoheisel, B Wiedenhöfer, S Mense

    This study investigated the nerve supply of the thoracolumbar fascia (TLF), the connective tissue of the low back, in both rats and humans. Researchers found that the fascia is richly innervated with sensory nerves, but…

    fasciaNociceptionThoracolumbar fascialow back painimmunohistochemistry
  7. A
    2011

    Fibroblast cytoskeletal remodeling contributes to connective tissue tension

    H M Langevin, N A Bouffard, J R Fox, B M Palmer, J Wu, J C Iatridis, W D Barnes, G J Badger, A K Howe

    The mechanical properties of connective tissue, such as its elasticity and resistance, have traditionally been attributed to its non-cellular matrix. This study investigated the role of fibroblasts, the cells residing w…

    fasciaConnective tissuefibroblastcytoskeletal remodeling
  8. A
    2011

    Remodeling and homeostasis of the extracellular matrix: implications for fibrotic diseases and cancer

    Thomas R Cox, Janine T Erler

    In this perspective article, the authors discuss how the extracellular matrix (ECM) is constantly being remodeled, a process essential for normal bodily functions like wound healing and tissue maintenance. When this rem…

    fasciaextracellular matrixcancerfibrosisstiffness
  9. A
    2011

    Hyaluronan as an Immune Regulator in Human Diseases

    Paul W Noble, Jiurong Liang, Dianhua Jiang

    This 2011 narrative review explores the role of hyaluronan (HA) in the immune system. While intact HA is a normal part of the extracellular matrix, fragments of HA produced during tissue injury can act as signals. These…

    hyaluronanfascia
  10. A
    2011

    Fascia and the mechanism of acupuncture

    Steven Finando, Donna Finando

    This theoretical paper re-evaluates the mechanisms of acupuncture. The authors propose that fascia, the body's connective tissue network, is the structure that explains how acupuncture works. They argue for this model b…

    fasciaacupunctureShamPlaceboMechanism
  11. A
    2011

    Chronic Disease: Are We Missing Something?

    James L Oschman

    This 2011 editorial by James L. Oschman poses a question in its title: "Chronic Disease: Are We Missing Something?". Without an abstract or full text available for summary, the specific perspective or argument presented…

    fasciachronic diseaseearthing
  12. A
    2011

    Hyaluronan in intestinal homeostasis and inflammation: implications for fibrosis

    Carol A de la Motte

    This narrative review explores the role of hyaluronan (HA) in intestinal health and disease. Chronic intestinal inflammation can lead to fibrosis, or scarring, a process driven by inflammatory signals and specialized ce…

    hafasciaextracellular matrixfibrosismesenchymal cells