Research.

Every peer-reviewed study on fascia in one place — graded for strength of evidence, summarised in plain language for clinicians, researchers, and curious readers.

We grade studies from A to 1A+++ using the Fascia Research Database rubric — 1A+++ is the strongest.

Researchers behind the studies

2,806

studies

602

top-graded

2,783

with plain-language summary

SortBy grade By year A–Z

View

Showing 145–156 of 181 studies · page 13/16fascia Since 2010

A
2012
Hyaluronic acid, A key molecule in skin aging
Eleni Papakonstantinou, Michael Roth, George Karakiulakis
This review article discusses the role of hyaluronic acid (HA) in skin aging. The authors explain that youthful skin's plumpness and resilience are largely due to its high water content, which HA is uniquely able to ret…
CD44fasciaHyaluronic acidhyaluronic acid synthaseshyaluronidases
1A+
2012
Stretching of the Back Improves Gait, Mechanical Sensitivity and Connective Tissue Inflammation in a Rodent Model
S M Corey, M A Vizzard, N A Bouffard, G J Badger, H M Langevin
In this rodent study, researchers investigated how stretching affects inflammation in the connective tissue of the low back. They first induced local inflammation, which resulted in altered gait, increased mechanical se…
fasciaConnective tissueStretchingManual TherapyMovement Therapy
A+
2012
The role of stromal cells in the persistence of chronic inflammation
A J Naylor, A Filer, C D Buckley
This review article explores why chronic inflammation often persists in specific anatomical locations. The authors highlight that stromal cells, particularly the fibroblasts that define a tissue's architecture, are like…
inflammationfasciafibroblastchronicpersistence
B
2012
Fascia: a morphological description and classification system based on a literature review
Myroslava Kumka, Jason Bonar
In this literature review, the authors address the historical problem of ambiguous and inconsistent terminology for fascia. Based on a review of existing research, they propose a new system for classifying fascia accord…
fasciaConnective tissueManual TherapyterminologyAnatomy
A
2012
Myoton Pro: A Novel Tool for the Assessment of Mechanical Properties of Fascial Tissues
Aleko Peipsi, Ricardas Kerpe, Heike Jäger, Sonja Soeder, Christopher Gordon, Robert Schleip
This research entry, for which only the title is available, appears to introduce a device called the MyotonPRO. The title suggests its purpose is to assess the mechanical properties of fascial tissues, such as their sti…
fasciaMyotone Pro
A++
2012
Lymphatic and interstitial flow in the tumour microenvironment: linking mechanobiology with immunity
Melody A Swartz, Amanda W Lund
This review explores how tumors interact with the lymphatic system to grow and spread. Increased fluid flow from a tumor to nearby lymph nodes does more than just transport cancer cells. This flow also creates mechanica…
fasciacancerstiffnessmechanobiologymicroenvironment
A
2012
A RHAMM Mimetic Peptide Blocks Hyaluronan Signaling and Reduces Inflammation and Fibrogenesis in Excisional Skin Wounds
Cornelia Tolg, Sara R Hamilton, Ewa Zalinska, Lori McCulloch, Ripal Amin, Natalia Akentieva, Francoise Winnik, Rashmin…
In this animal study, researchers investigated how to reduce scarring during skin wound healing. They developed a peptide, P15-1, designed to interfere with signals from fragmented hyaluronan, a molecule involved in inf…
hyaluronaninflammationfasciaextracellular matrixfibrosis
1A+++
2011
Hyaluronan within fascia in the etiology of myofascial pain
Carla Stecco, R Stern, A Porzionato, V Macchi, S Masiero, Antonio Stecco, R De Caro
In this cadaver and ultrasound study, researchers examined the composition of deep fascia. They identified layers of hyaluronan (HA), a lubricating substance, between the fascia and muscle, as well as between the fascia…
fasciaHyaluronic acidSliding systemLoose connective tissueFasciacyte
B
2011
Fascia Research from a Clinician/Scientist’s Perspective
Thomas W Findley
In this perspective piece, a clinician-scientist summarizes exciting areas in fascia research. The article describes the fascial network as a body-wide system that connects individual cells and shares loads with muscles…
fasciaTensegritycollagenfibroblastconference
A
2011
Pandiculation: Nature’s way of maintaining the functional integrity of the myofascial system?
Luiz Fernando Bertolucci
This paper explores the hypothesis that pandiculation—the involuntary stretching and yawning most animals do upon waking—serves a key role for the locomotor system. Beyond preparing the nervous system for wakefulness, t…
fasciaConnective tissuemyofasciayawningsleep-wake rhythm
A
2011
High and Low Molecular Weight Hyaluronic Acid Differentially Regulate Human Fibrocyte Differentiation
A S Maharjan, D Pilling, R H Gomer
Following tissue injury, immune cells called monocytes can differentiate into fibrocytes, a cell type involved in healing and fibrosis. This study investigated how different sizes of hyaluronic acid (HA) affect this pro…
hyaluronanfasciafibrocyte differentiationmonocyte
A
2011
Fibroblasts and Myofibroblasts: What are we talking about?
Jennifer Baum, Heather S Duffy
This 2011 narrative review explores the roles of fibroblasts and myofibroblasts, two key cell types in the heart's connective tissue. Once considered static, research indicates these cells are dynamic and play an active…
fasciafibroblastMyofibroblast