Research.
Every peer-reviewed study on fascia in one place — graded for strength of evidence, summarised in plain language for clinicians, researchers, and curious readers.
We grade studies from A to 1A+++ using the Fascia Research Database rubric — 1A+++ is the strongest.
Researchers behind the studiesNew Proposal to Define the Fascial System
In this proposal, the authors suggest a new definition for the fascial system, noting that a universally accepted one does not yet exist. They argue for including the epidermis (the outer layer of skin) based on functio…
The myodural bridge in the common rock pigeon (Columbia livia): Morphology and possible physiological implications
In this anatomical study on pigeons, researchers investigated a connective tissue structure called the myodural bridge. Through dissections and tissue analysis of the suboccipital region where the skull meets the neck,…
Human Recombinant Hyaluronidase Injections For Upper Limb Muscle Stiffness in Individuals With Cerebral Injury: A Case Series
This case series investigated injections of the enzyme hyaluronidase to treat upper limb muscle stiffness in 20 individuals with cerebral injury. The researchers hypothesized that an accumulation of hyaluronan in the mu…
A Systematic Review of the Soft-Tissue Connections Between Neck Muscles and Dura Mater
In this systematic review, researchers compiled data from 26 studies to investigate direct soft-tissue connections between neck muscles and the dura mater, the outermost membrane surrounding the spinal cord. The analysi…
Fascia—Current knowledge and future directions in physiatry: Narrative review
In this 2014 narrative review, the authors discuss fascia from the perspective of physiatry, or rehabilitation medicine. They note that while fascia is part of the body's connective tissue, its definition is unclear in…
Cellulite's aetiology: a review
In this literature review, researchers examined the underlying causes of cellulite. They found that cellulite is a complex phenomenon with many interacting factors, rather than a single cause. The research points to wom…
Cellular Control of Connective Tissue Matrix Tension
This review article explores how fibroblasts, the cells within connective tissue, actively help regulate tissue tension. Traditionally, the mechanical properties of connective tissue have been attributed to its passive…
Dynamic fascial release and the role of mechanical/vibrational assist devices in manual therapies
This review article explores the use of mechanical vibration devices in manual therapy. The author examines several such tools, including percussion vibrators, vibrational platforms, and deep tissue oscillation. The art…
Pandiculation: Nature’s way of maintaining the functional integrity of the myofascial system?
This paper explores the hypothesis that pandiculation—the involuntary stretching and yawning most animals do upon waking—serves a key role for the locomotor system. Beyond preparing the nervous system for wakefulness, t…
Sensory Innervation of the Nonspecialized Connective Tissues in the Low Back of the Rat
In this animal study, researchers investigated the sensory nerves in the nonspecialized connective tissue of the rat low back, an area where knowledge is limited. Using 3D reconstruction and dye-labeling techniques, the…
Fibroblast cytoskeletal remodeling contributes to connective tissue tension
The mechanical properties of connective tissue, such as its elasticity and resistance, have traditionally been attributed to its non-cellular matrix. This study investigated the role of fibroblasts, the cells residing w…
Edema and fluid dynamics in connective tissue remodelling
This review describes the role of loose connective tissues, focusing on fluid exchange across capillaries and the formation of edema (swelling). This process is relevant for conditions like inflammation, fibrosis (scarr…