Research.

Every peer-reviewed study on fascia in one place — graded for strength of evidence, summarised in plain language for clinicians, researchers, and curious readers.

We grade studies from A to 1A+++ using the Fascia Research Database rubric — 1A+++ is the strongest.

Researchers behind the studies

2,806

studies

602

top-graded

2,783

with plain-language summary

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Showing 1–12 of 15 studies · page 1/2Connective tissue A Since 2010

A
2018
New Proposal to Define the Fascial System
Bruno Bordoni, Fabiola Marelli, Bruno Morabito, Roberto Castagna, Beatrice Sacconi, Paul Mazzucco
In this proposal, the authors suggest a new definition for the fascial system, noting that a universally accepted one does not yet exist. They argue for including the epidermis (the outer layer of skin) based on functio…
fasciaConnective tissuefibroblastMyofascialSkin
A
2018
The myodural bridge in the common rock pigeon (Columbia livia): Morphology and possible physiological implications
Chukwuemeka Samuel Okoye, Nan Zheng, Sheng-Bo Yu, Hong-Jin Sui
In this anatomical study on pigeons, researchers investigated a connective tissue structure called the myodural bridge. Through dissections and tissue analysis of the suboccipital region where the skull meets the neck,…
Connective tissuecerebrospinal fluiddura materbirdhistological sections
A
2016
Human Recombinant Hyaluronidase Injections For Upper Limb Muscle Stiffness in Individuals With Cerebral Injury: A Case Series
Preeti Raghavan, Ying Lu, Mona Mirchandani, Antonio Stecco
This case series investigated injections of the enzyme hyaluronidase to treat upper limb muscle stiffness in 20 individuals with cerebral injury. The researchers hypothesized that an accumulation of hyaluronan in the mu…
fasciaConnective tissueStrokeHypertoniaspasticity
A
2016
A Systematic Review of the Soft-Tissue Connections Between Neck Muscles and Dura Mater
Luis Palomeque-del-Cerro, Luis A Arráez-Aybar, Cleofás Rodriguez-Blanco, Rafael Guzmán-Garcia, Mar Menendez-Aparicio, Á…
In this systematic review, researchers compiled data from 26 studies to investigate direct soft-tissue connections between neck muscles and the dura mater, the outermost membrane surrounding the spinal cord. The analysi…
fasciaConnective tissueproprioceptionSpineAnatomy
A
2014
Fascia—Current knowledge and future directions in physiatry: Narrative review
E H Kwong, T W Findley
In this 2014 narrative review, the authors discuss fascia from the perspective of physiatry, or rehabilitation medicine. They note that while fascia is part of the body's connective tissue, its definition is unclear in…
fasciaHyaluronic acidConnective tissuefibroblastmechanotransduction
A
2013
Cellulite's aetiology: a review
M de la Casa Almeida, Suarez Serrano, J Rebollo Roldán, J J Jiménez Rejano
In this literature review, researchers examined the underlying causes of cellulite. They found that cellulite is a complex phenomenon with many interacting factors, rather than a single cause. The research points to wom…
Connective tissuecellulites
A
2013
Cellular Control of Connective Tissue Matrix Tension
H M Langevin, M Nedergaard, A Howe
This review article explores how fibroblasts, the cells within connective tissue, actively help regulate tissue tension. Traditionally, the mechanical properties of connective tissue have been attributed to its passive…
Connective tissuefibroblastmechanicalatpcytoskeleton
A
2011
Fibroblast cytoskeletal remodeling contributes to connective tissue tension
H M Langevin, N A Bouffard, J R Fox, B M Palmer, J Wu, J C Iatridis, W D Barnes, G J Badger, A K Howe
The mechanical properties of connective tissue, such as its elasticity and resistance, have traditionally been attributed to its non-cellular matrix. This study investigated the role of fibroblasts, the cells residing w…
fasciaConnective tissuefibroblastcytoskeletal remodeling
A
2011
Pandiculation: Nature’s way of maintaining the functional integrity of the myofascial system?
Luiz Fernando Bertolucci
This paper explores the hypothesis that pandiculation—the involuntary stretching and yawning most animals do upon waking—serves a key role for the locomotor system. Beyond preparing the nervous system for wakefulness, t…
fasciaConnective tissuemyofasciayawningsleep-wake rhythm
A
2011
Dynamic fascial release and the role of mechanical/vibrational assist devices in manual therapies
Zachary Comeaux
This review article explores the use of mechanical vibration devices in manual therapy. The author examines several such tools, including percussion vibrators, vibrational platforms, and deep tissue oscillation. The art…
fasciaConnective tissuevibrationpercussion vibrationtonic vibratory reflex
A
2011
Sensory Innervation of the Nonspecialized Connective Tissues in the Low Back of the Rat
Sarah M Corey, Margaret A Vizzard, Gary J Badger, Helene M Langevin
In this animal study, researchers investigated the sensory nerves in the nonspecialized connective tissue of the rat low back, an area where knowledge is limited. Using 3D reconstruction and dye-labeling techniques, the…
fasciaConnective tissueinnervationlow back painmusculoskeletal pain
A
2010
Transcapillary exchange: role and importance of the interstitial fluid pressure and the extracellular matrix
Rolf K Reed, Kristofer Rubin
This narrative review discusses how the extracellular matrix (ECM) and the pressure of its fluid (interstitial fluid pressure, or Pif) regulate fluid exchange with capillaries. Conventionally, this pressure is seen as a…
inflammationConnective tissueglycosaminoglycansbeta-Integrin receptors