Research.
Every peer-reviewed study on fascia in one place — graded for strength of evidence, summarised in plain language for clinicians, researchers, and curious readers.
We grade studies from A to 1A+++ using the Fascia Research Database rubric — 1A+++ is the strongest.
Researchers behind the studies- A2019
Myofascial Chains of the Upper Limb: A Systematic Review of Anatomical Studies
JAN WILKE, FRIEDER KRAUSEThis systematic review compiled research to determine if myofascial chains, previously identified in the trunk and lower limbs, also exist in the upper limb. Analyzing 13 anatomical dissection studies, the authors found…
continuity; fascia; force transmission; muscles; cadavers; connective tissue; myofascial chains - A2019
Intravascular heavy chain-modification of hyaluronan during endotoxic shock
Kevin Ni, Amar Gill, Danting Cao, Kengo Koike, Kelly S Schweitzer, Stavros Garantziotis, Irina PetracheIn this animal study, researchers investigated why a specific molecule, HC-modified hyaluronan (HC-HA), is critical for survival in systemic inflammation (like endotoxic shock) but less so in localized lung inflammation…
Hyaluronic acidInter-alpha-inhibitorSerum-derived hyaluronan-associated proteinTNFα stimulated gene 6Endotoxic shock - A2019
Benefits of adding stretching to a moderate-intensity aerobic exercise programme in women with fibromyalgia: a randomized controlled trial
Miguel Gómez-Hernández, Tomás Gallego-Izquierdo, Patricia Martínez-Merinero, Daniel Pecos-Martín, Alejandro Ferragut-Ga…This randomized controlled trial investigated whether adding stretching to a moderate-intensity aerobic exercise program provided extra benefits for women with fibromyalgia. One group performed moderate aerobic exercise…
FibromyalgiaStretchingpainsleep qualityquality of life - A2019
Adhesive capsulitis: MRI correlation with clinical stages and proposal of MRI staging
Amarnath Chellathurai, Komalavalli Subbiah, Atchaya Elangovan,, Sivakumar KannappanThis study investigated whether magnetic resonance imaging (MRI) findings can reflect the clinical stages of adhesive capsulitis, also known as frozen shoulder. Researchers analyzed MRIs from 74 patients, looking for sp…
Adhesive capsulitis; MRI staging; magnetic resonance imaging; frozen shoulder - A2019
Innervation of the thoracolumbar fascia
Siegfried MenseThis study, conducted primarily on rats, investigated the types of nerves in the thoracolumbar fascia (TLF) to better understand its sensory roles. Researchers found only free nerve endings, many of which are associated…
NociceptionThoracolumbar fasciainnervationfree nerve endingsproprioception - A2019
Dermatome and Fasciatome
Carla Stecco, Carmelo Pirri, Caterina Fede, Chenglei Fan, Federico Giordani, Luigi Stecco, Calogero Foti, Raffaele De C…This theoretical paper proposes a new distinction between the body's sensory maps, based on increased knowledge of fascial innervation. The authors define a "dermatome" as the area of skin and superficial fascia supplie…
fascia; dermatome; nerve; pain; proprioception - A2019
High-dose vitamin C suppresses the invasion and metastasis of breast cancer cells via inhibiting epithelial-mesenchymal transition
Ling-Hui Zeng, Qing-Mei Wang, Lin-Yi Feng, Yu-Dun Ke, Qian-Zi Xu, An-Yi Wei, Chong Zhang, Rong-Biao YingThis study on breast cancer cells in the lab and in mice explored how different doses of vitamin C affect cancer cell behavior. Researchers found that low and medium doses of vitamin C seemed to encourage cancer cells t…
Breast cancermetastasisTGF-β1Vitamin C - A2019
Putative Primo-Vascular System in Rabbit Placenta
Fatma El-Zahraa A MustafaIn this animal study, researchers investigated the primo vascular system (PVS), a proposed network that may play a role in transport, tissue regeneration, and cell migration. While the PVS has been detected in other rab…
inflammatory cell; placenta; primo vascular system; primo vessel; rabbit. - A2019
Ultrasound Imaging of the Fascial Layers
Carmelo Pirri, Carla Stecco, Levent ÖzçakarThis publication, for which a full summary is not yet available, appears to discuss using ultrasound to visualize the body's fascial layers. Ultrasound imaging is a non-invasive technique that provides real-time views o…
ultrasound.fascial layers - A2019
Where is your head? Perception of relative position of the head on a wielded object
Jeffrey B Wagman, Takahiro HiguchiThis study explored how we perceive our body's position relative to an object we are holding or balancing. Researchers specifically tested this by having participants "wield" an object with their head, a body part not t…
Haptics . Perception and action . Touch - A2019
Role of Hyaluronan in Inflammatory Effects on Human Articular Chondrocytes
Mary K Cowman, Claire Shortt, Shivani Arora, Yuhong Fu, Jemma Villavieja, Jai Rathore, Xiayun Huang, Tatini Rakshit, Gy…Some researchers have proposed that fragments of hyaluronan (HA), a key molecule in connective tissue, can trigger inflammation in cartilage. This study investigated that idea in human articular cartilage cells. Researc…
hyaluronan; hyaluronidase; articular cartilage; chondrocytes; inflammation - A2019
Hyaluronan/collagen hydrogels containing sulfated hyaluronan improve wound healing by sustained release of heparin-binding EGF-like growth factor
Stephan Thönes, Sandra Rother, Tom Wippold, Joanna Blaszkiewicz, Kanagasabai Balamurugan, Stephanie Moeller, Gloria Rui…This study investigated a new type of hydrogel designed to improve wound healing. Researchers combined collagen and hyaluronan (HA), a natural component of connective tissue, with a growth factor that stimulates skin ce…
Biomimetic material; Extracellular matrix (ECM); Fibroblasts; Heparin-binding epidermal growth factor-like growth factor (HB-EGF); Hyaluronan; Hydrogel; Sulfated hyaluronan; Surface plasmon resonance; Wound healing.