Research.
Every peer-reviewed study on fascia in one place — graded for strength of evidence, summarised in plain language for clinicians, researchers, and curious readers.
We grade studies from A to 1A+++ using the Fascia Research Database rubric — 1A+++ is the strongest.
Researchers behind the studies- A2012
Real-time imaging of cortical areas involved in the generation of increases in skin sympathetic nerve activity when viewing emotionally charged images
Luke A Henderson, Alexandra Stathis, Cheree James, Rachael Brown, Skye McDonald, Vaughan G MacefieldThis study investigated which brain regions are involved when our bodies react to emotional images. Researchers simultaneously measured brain activity with fMRI and skin sympathetic nerve activity (SSNA), a marker of th…
fasciaMRIIASP imagesmicroneurographyskin sympathetic nerve activity - A2012
CTGF is a central mediator of tissue remodeling and fibrosis and its inhibition can reverse the process of fibrosis
Kenneth E Lipson, Carol Wong, Yuchin Teng, Suzanne SpongFibrosis is a process of excessive connective tissue formation, leading to scarring and stiffness in organs. A protein called Connective Tissue Growth Factor (CTGF) plays a central role in driving this process. This res…
extracellular matrixfibrosisfascia CTGFtissue remodeling - A2012
The thoracolumbar fascia: anatomy, function and clinical considerations
Frank H Willard, Andry Vleeming, M D Schuenke, L Danneels, Robert SchleipThis overview paper examines the anatomy and function of the thoracolumbar fascia (TLF), the complex sheet of connective tissue in the lower back. The authors describe its multiple layers, which separate and connect the…
fasciathoracolumbarfascia - A2012
Human myometrium – the ultrastructural 3D network of telocytes
Sanda M Cretoiu, Dragos Cretoiu, Laurentiu M PopescuThis study examined a relatively new type of cell, the telocyte, within the human myometrium, the muscular layer of the uterus. Using advanced microscopy, researchers visualized these cells and their very long extension…
telocytes ! telopodes ! podoms ! podomers ! human uterus ! extracellular vesicles - A2011
Assessing the influence of FDM to the postoperative healing processes in distal fracture of the radius
Tomasz TesznerResearchers investigated if the Fascial Distortion Model (FDM) could improve recovery following surgery for a common wrist fracture. In this study, 65 patients were divided into two groups; one received standard rehabil…
fasciaManual Therapyfasciaefascial distortion modelreductionism - A2011
Correlations Between Fasciology and Yin Yang Doctrine
Hui Tao, Mei-Chun Yu, Hui-Ying Yang, Rong-Mei Qu, Chun Yang, Xin Zhou, Yu Bai, Jing-Peng Wu, Jun Wang, Ou Sha, Lin YuanThis theoretical paper explores correlations between "fasciology," a model based on 3D reconstruction of connective tissue, and the traditional Chinese doctrine of yin and yang. According to fasciology, the body can be…
fasciafasciologyfascial anatomytwo-system theoryyin yang doctrine - A2011
Elevated [11C]-D-Deprenyl Uptake in Chronic Whiplash Associated Disorder Suggests Persistent Musculoskeletal Inflammation
Clas Linnman, Lieuwe Appel, Mats Fredrikson, Torsten Gordh, Anne Söderlund, Bengt Långström, Henry EnglerDiagnosing chronic whiplash-associated disorder (WAD) is often difficult, as standard structural imaging methods seldom show clear signs of injury. This study used Positron Emission Tomography (PET) with a tracer molecu…
inflammationfasciaWhiplash - A2011
Remodeling and homeostasis of the extracellular matrix: implications for fibrotic diseases and cancer
Thomas R Cox, Janine T ErlerIn this perspective article, the authors discuss how the extracellular matrix (ECM) is constantly being remodeled, a process essential for normal bodily functions like wound healing and tissue maintenance. When this rem…
fasciaextracellular matrixcancerfibrosisstiffness - A2011
Sensory Innervation of the Thoracolumbar Fascia in Rats and Humans
J Tesarz, U Hoheisel, B Wiedenhöfer, S MenseThis study investigated the nerve supply of the thoracolumbar fascia (TLF), the connective tissue of the low back, in both rats and humans. Researchers found that the fascia is richly innervated with sensory nerves, but…
fasciaNociceptionThoracolumbar fascialow back painimmunohistochemistry - A2011
Exercise training reduces fibrosis and matrix metalloproteinase dysregulation in the aging rat heart
Hyo-Bum Kwak, Jong-hee Kim, Kumar Joshi, Alvin Yeh, Daniel A Martinez, John M LawlerIn this animal study, researchers investigated how exercise affects age-related fibrosis (scarring) in the rat heart. They found that aging was associated with an increase in collagen and a dysregulation of enzymes call…
collagenRemodelingTIMP-1 - A2011
Correlation of MR Arthrographic Findings and Range of Shoulder Motions in Patients With Frozen Shoulder
So-Yeon Lee, Jeongmi Park, Seok-Whan SongThis study investigated the relationship between findings on MR arthrography (a type of MRI) and range of motion in people with frozen shoulder. Researchers measured the thickness of two structures: the coracohumeral li…
MRIfrozen shoulderAdhesive capsulitiscoracohumeral ligament - A2011
The Genetics of Vitamin C Loss in Vertebrates
Guy Drouin, Jean-Rémi Godin, Benoît PagéThis narrative review explores why some vertebrate species, including humans, cannot produce their own Vitamin C. The inability to synthesize this crucial nutrient, important for collagen and antioxidant functions, stem…
BiosynthesisVitamin CAscorbic acidGLO geneL-gulono-gamma-lactone oxidase
