Research.
Every peer-reviewed study on fascia in one place — graded for strength of evidence, summarised in plain language for clinicians, researchers, and curious readers.
We grade studies from A to 1A+++ using the Fascia Research Database rubric — 1A+++ is the strongest.
Researchers behind the studies- A2013
Helical Structure of the Cardiac Ventricular Anatomy Assessed by Diffusion Tensor Magnetic Resonance Imaging With Multiresolution Tractography
Ferran Poveda, Debora Gil, Enric Marti, Albert,aluz, Manel Ballester, Francesc CarrerasIn this animal study, researchers used advanced magnetic resonance imaging (MRI) and computer modeling to visualize the complex fiber structure of the heart muscle in dogs. They developed an automated method to trace th…
fasciaheartifdfusion magnetic resonance imagingdiffusion tractographyhelical heart - A2013
Fascia Research Congress Evidence from the 100 year perspective of Andrew Taylor Still
Thomas W Findley, Mona ShalwalaThis review paper examines research from the first three International Fascia Research Congresses through the perspective of Andrew Taylor Still, the founder of osteopathic medicine. Over a century ago, Still described…
fasciaextracellular matrixfibroblastOsteopathic medicinefascia anatomy - A2013
Telocytes: ultrastructural, immunohistochemical and electrophysiological characteristics in human myometrium
Sanda M Cretoiu, Dragos Cretoiu, Adela Marin, Beatrice Mihaela Radu, Laurentiu M PopescuThis study identifies a specific cell type, telocytes, within the muscular wall of both the pregnant and non-pregnant human uterus. Researchers found that these cells have a different structure depending on whether the…
telocytesuterine - A2013
Cellular Control of Connective Tissue Matrix Tension
H M Langevin, M Nedergaard, A HoweThis review article explores how fibroblasts, the cells within connective tissue, actively help regulate tissue tension. Traditionally, the mechanical properties of connective tissue have been attributed to its passive…
Connective tissuefibroblastmechanicalatpcytoskeleton - A2013
The Primo Vascular System as a New Anatomical System
Miroslav Stefanov, Michael Potroz, Jungdae Kim, Jake Lim, Richard Cha, Min-Ho NamThis review paper proposes the existence of a "primo vascular system" (PVS) as the physical, anatomical basis for the meridian system of traditional Eastern medicine. According to the authors, this previously unknown sy…
fasciaEvolutioncirculatory systemnew morphologicalfunctional theory - A2013
A Randomized Steady-State Bioavailability Study of Synthetic versus Natural (Kiwifruit-Derived) Vitamin C
Anitra C Carr, Stephanie M Bozonet, Juliet M Pullar, Jeremy W Simcock, Margreet C M VissersThis randomized study investigated whether the body absorbs vitamin C from kiwifruit as effectively as from a synthetic supplement. Thirty-six young men received either half a kiwifruit or an equivalent dose (50 mg) vit…
ascorbate; ascorbic acid; human; plasma; urine; semen; leukocytes; skeletal muscle - A2013
Metabolic control of hyaluronan synthases
Davide Vigetti, Manuela Viola, Evgenia Karousou, Giancarlo De Luca, Alberto PassiThis narrative review explores how a cell's energy and nutritional status regulate the production of hyaluronan (HA), a key component of the extracellular matrix. HA is synthesized by enzymes called HAS, which require s…
fasciaGlycosaminoglycanO-GlcNacylationUDP-GlcUAUDP-GlcNA - A2013
Plantar fascia anatomy and its relationship with Achilles tendon and paratenon
Carla Stecco, Marco Corradin, Veronica Macchi, Aldo Morra, Andrea Porzionato, Carlo Biz, Raffaele De CaroThis study investigated the detailed anatomy of the plantar fascia and its connection to the Achilles tendon. Dissections of human cadavers revealed that the fascia is more closely linked to the paratenon (the tendon's…
hyaluronanfasciaFasciacyteachilles tendonparatenon - A2013
Applications and Emerging Trends of Hyaluronic Acid in Tissue Engineering, as a Dermal Filler, and in Osteoarthritis Treatment
Amir Fakhari, Cory BerklandThis narrative review summarizes knowledge about hyaluronic acid (HA), a naturally occurring polymer found in the body's connective tissues and fluids. The authors describe how HA contributes to the structural propertie…
fasciaHyaluronic acidcrosslinkingdermal fillerviscosupplement - A2013
Histological analysis of the rectus capitis posterior major’s myodural bridge
Frank Scali, Matthew E Pontell, Dennis E Enix, Ewarld MarshallThis cadaver study investigated a small tissue bridge between a suboccipital muscle (rectus capitis posterior major) and the dura mater, the protective covering of the spinal cord. Using microscopic analysis on tissue f…
fasciacervical spinerectus capitis posterior majorMyodural Bridgecervical dura mater - A2013
Human skeletal muscle ascorbate is highly responsive to changes in vitamin C intake and plasma concentrations
Anitra C Carr, Stephanie M Bozonet, Juliet M Pullar, Jeremy W Simcock, Margreet C M VissersThis study investigated how vitamin C intake affects its concentration in human skeletal muscle. Researchers gave 36 men either half a kiwifruit or two kiwifruits daily for six weeks, as kiwifruit is a rich source of vi…
Vitamin Cascorbate - A2013
Hyaluronan: A Simple Polysaccharide with Diverse Biological Functions
Kevin T Dicker, Lisa A Gurski, Swati Pradhan-Bhatt, Robert L Witt, Mary C Farach-Carson, Xinqiao JiaThis review paper describes hyaluronan (HA), a simple sugar molecule found abundantly throughout the body's connective tissues. Despite its simple structure, HA has a surprising array of biological functions. It helps o…
hyaluronanfasciawound healingsynthasehyaluronidase