Research.
Every peer-reviewed study on fascia in one place — graded for strength of evidence, summarised in plain language for clinicians, researchers, and curious readers.
We grade studies from A to 1A+++ using the Fascia Research Database rubric — 1A+++ is the strongest.
Researchers behind the studies- A2014
Clinical Relevance of Fascial Tissue and Dysfunctions
Werner Klingler, M Velders, K Hoppe, M Pedro, Robert SchleipFascia is a continuous network of connective tissue that supports the entire body. Traditionally seen as a passive structure, recent research shows it plays a more active role. Fascia contains contractile elements that…
fasciaMyofascial painlumbar fasciadysfunction - A2014
Whey protein hydrolysate augments tendon and muscle hypertrophy independent of resistance exercise contraction mode
J Farup, S K Rahbek, M H Vendelbo, A Matzon, J Hindhede, A Bejder, S Ringgard, K VissingThis study investigated the effects of resistance training combined with either whey protein or a placebo on muscle and tendon growth. Twenty-two participants performed 12 weeks of knee extension training, using eccentr…
patellar tendonstrength trainingeccentric trainingconcentric trainingrate of force development - A2014
Deformations Experienced in the Human Skin, Adipose Tissue, and Fascia in Osteopathic Manipulative Medicine
Hans Chaudhry, Bruce Bukiet, Zhiming Ji, Antonio Stecco, Thomas W FindleyThis study used a mathematical model to investigate how forces from manual therapy affect the skin, adipose tissue, and fascia. The researchers aimed to understand how much each layer deforms under compression and shear…
fasciaosteopathyManual Therapy - A2014
The cervical myodural bridge, a review of literature and clinical implications
Dennis E Enix, Frank Scali, Matthew E PontellThis literature review examines the cervical myodural bridge, a soft tissue connection between deep suboccipital muscles and the dura mater surrounding the spinal cord. This bridge appears to anchor the spinal cord and…
fasciarectus capitis posterior majordura materMyodural Bridgeobliquus capitis inferior - A2014
Primary frozen shoulder: brief review of pathology and imaging abnormalities
Kazuya Tamai, Miwa Akutsu, Yuichiro YanoThis narrative review examines the underlying pathology of primary frozen shoulder, a condition causing spontaneous pain and stiffness in the shoulder joint. The authors summarize evidence indicating that the main issue…
frozen shoulderAdhesive capsulitisShoulder painTherapy - A2014
Hyaluronan Synthase 2 Protects Skin Fibroblasts against Apoptosis Induced by Environmental Stress
Yan Wang, Mark E Lauer, Sanjay Anand, Judith A Mack, Edward V MaytinSkin fibroblasts need to manage environmental stress, such as UV radiation. This study on mouse cells investigated how hyaluronan (HA) and the enzymes that produce it help fibroblasts survive. Researchers found that cel…
Apoptosis; Caspase; Extracellular Matrix; Fibroblast; Hyaluronan; Skin; Stress. - A2014
Chiropractic Management of Pubic Symphysis Shear Dysfunction in a Patient With Overactive Bladder
Robert Cooperstein, Anthony Lisi, Andrew BurdThis case report describes the chiropractic care of a 24-year-old woman with an overactive bladder, specifically frequent nighttime urination that disrupted her sleep. A physical examination revealed a shear dysfunction…
fasciasymphysis pubis dysfunctionpubic symphysispubic symphysis diastasisurinary bladder overactive - A2014
Fascia—Current knowledge and future directions in physiatry: Narrative review
E H Kwong, T W FindleyIn this 2014 narrative review, the authors discuss fascia from the perspective of physiatry, or rehabilitation medicine. They note that while fascia is part of the body's connective tissue, its definition is unclear in…
fasciaHyaluronic acidConnective tissuefibroblastmechanotransduction - A2014
Uptake and intracytoplasmic storage of pigmented particles by human CD34+ stromal cells/telocytes: endocytic property of telocytes
Lucio Díaz-Flores, Ricardo Gutiérrez, M Pino García, Francisco J Sáez, Fernando Aparicio, Lucio Díaz-Flores Jr, Juan F…Researchers investigated whether a specific type of connective tissue cell, called a telocyte, could absorb foreign particles. They examined human colon tissue that had been injected with India ink as a surgical marker.…
CD34+ stromal cells; colon; endocytosis; phagocytosis; skin; telocytes. - A2014
The effectiveness of exercise interventions to prevent sports injuries: a systematic review and meta-analysis of randomised controlled trials
Jeppe Bo Lauersen, Ditte Marie Bertelsen, Lars Bo AndersenThis systematic review and meta-analysis examined 25 studies to evaluate which types of exercise best prevent sports injuries. The analysis included over 26,000 participants and data on more than 3,400 injuries. Researc…
exercisesinjury prevention - A2014
Mechanotransduction and extracellular matrix homeostasis
Jay D Humphrey, Eric R Dufresne, Martin A SchwartzConnective tissues are dynamic, constantly adapting even at rest. Cells within these tissues continually sense mechanical cues from their environment through a process called mechanotransduction. In response, they maint…
fasciaextracellular matrixIntegrinsmechanosensingmechanoregulation - A2014
Specific Sizes of Hyaluronan Oligosaccharides Stimulate Fibroblast Migration and Excisional Wound Repair
C Tolg, P Telmer, E TurleyHyaluronan (HA) is a molecule important for wound healing, and its effects appear to depend on its size. In this study using cell cultures and animal models, researchers investigated how specific, small fragments of HA…
fasciahyaluronan molecular sizehyaluronan fragmentswound healing
