Research.
Every peer-reviewed study on fascia in one place — graded for strength of evidence, summarised in plain language for clinicians, researchers, and curious readers.
We grade studies from A to 1A+++ using the Fascia Research Database rubric — 1A+++ is the strongest.
Researchers behind the studies- A2015
Modeled Osteopathic Manipulative Treatments: A Review of Their in Vitro Effects on Fibroblast Tissue Preparations
Manal Zein-Hammoud, Paul R StandleyThis narrative review summarizes lab-based (in vitro) studies investigating how simulated osteopathic treatments, like myofascial release, affect fibroblasts. The authors found that applying mechanical strain to these c…
fasciaFibroblastsManual TherapyOsteopathic - A2015
Sensory Nerve Fibers Containing Calcitonin Gene-Related Peptide in Gastrocnemius, Latissimus Dorsi and Erector Spinae Muscles and Thoracolumbar Fascia in Mice
C M Barry, G Kestell, M Gillan, R V Haberberger, I L GibbinsIn this animal study, researchers investigated sensory nerve fibers containing CGRP, a peptide involved in pain signaling. They compared the presence of these nerve fibers in various muscles (gastrocnemius, latissimus d…
fasciaBack PainThoracolumbar fasciaimmunohistochemistrysensory innervation - A2015
Tracking CNS and systemic sources of oxidative stress during the course of chronic neuroinflammation
Agata A Mossakowski, Julian Pohlan, Daniel Bremer, Randall Lindquist, Jason M Millward, Markus Bock, Karolin Pollok, Ro…In this animal study, researchers used a mouse model for multiple sclerosis (MS) to track the sources of oxidative stress in the central nervous system. Using an advanced imaging technique, they identified specific immu…
Multiple sclerosis · Oxidative stress · Neuronal dysfunction · Fluorescence lifetime microscopy · Intravital imaging · Oxidative stress memory - A2015
Cellulite treatment: a comprehensive literature review
Irene Zerini, Andrea Sisti, Roberto Cuomo, Serena Ciappi, Francesco Russo, Cesare Brandi, Carlo D’Aniello, Giuseppe NisiIn this 2015 literature review, researchers compiled the results from various cellulite treatments. They analyzed 73 clinical studies involving human subjects, most of whom were women. The evaluated treatments included…
elasticitycellulitefatty tissue - A2015
The fascial system and exercise intolerance in patients with chronic heart failure: hypothesis of osteopathic treatment
Bruno Bordoni, F MarelliThis hypothesis paper proposes a connection between the fascial system and exercise intolerance in people with chronic heart failure. The authors note that heart failure is a complex disease affecting the entire body, l…
fasciaManual TherapyOsteopathicfatiguechronic heart failure - A2015
New Developments in the Primo Vascular System: Imaging and Functions with regard to Acupuncture
Richard C Niemtzow, Kwang-Sup Soh, Kyung A Kang, John H Barker, He Sheng Luo, Moriya OhkumaThis research entry, for which only the title is available, appears to discuss recent advancements in understanding the primo vascular system. The title suggests a focus on new imaging techniques and the system's functi…
acupunctureprimo vascular systemeditorial - A2015
Effects of non-pharmacological interventions on inflammatory biomarker expression in patients with fibromyalgia: a systematic review
Kenji Sanada, Marta Alda Díez, Montserrat Salas Valero, María Cruz Pérez-Yus, Marcelo M P Demarzo, Mauro García-Toro, J…This systematic review examined how non-drug treatments affect inflammatory markers in people with fibromyalgia. Researchers analyzed 12 studies involving 536 participants who underwent exercise, dietary, or multidiscip…
fasciaFibromyalgiapaincytokinessleep quality - A2014
Vitamin C in the Treatment and/or Prevention of Obesity
Diego Fernando GARCIA-DIAZ, Patricia LOPEZ-LEGARREA, Pablo QUINTERO, Jose Alfredo MARTINEZIn this 2014 narrative review, the authors examine the relationship between vitamin C and obesity. Obesity is often linked to oxidative stress, which can lead to other health issues like diabetes and cardiovascular dise…
Oxidative stressAscorbic acidantioxidantbody weight - A2014
Biotensegrity of the extracellular matrix: physiology, dynamic mechanical balance, and implications in oncology and mechanotherapy
Irene Tadeo, Ana P Berbegall, Luis M Escudero,Tomás Álvaro, Rosa NogueraThis 2014 review article explores the concept of biotensegrity, a principle where cells and tissues maintain structural integrity through a balance of tension and compression. This dynamic mechanical balance involves th…
fasciaextracellular matrixcancerbiotensegritymechanotherapy - A2014
Antioxidants in health and disease
E Ginter, V Simko, V PanakovaThis narrative review summarizes research on antioxidants published since 2010. The main role of antioxidants is to neutralize reactive oxygen species (ROS), which are linked to conditions like cardiovascular disease, c…
antioxidantsreactive oxygen species (ROS)vitamin C and Ecarotenoidspolyphenols - A2014
Fat Connected with the Primo Vascular System
Kyoung-Hee Bae, Kwang-Sup SohThis research entry is currently available as a title only, so a detailed summary is not yet possible. The title, "Fat Connected with the Primo Vascular System," suggests an investigation into the relationship between a…
fasciafatadipose tissueprimo vascular system (PVS) - A2014
Lumbopelvic muscle activation patterns in three stances under graded loading conditions: Proposing a tensegrity model for load transfer through the sacroiliac joints
Hamed Pardehshenas, Nader Maroufi, Mohammad Ali Sanjari, Mohamad Parnianpour, Stephen M LevinResearchers investigated how lumbopelvic muscles activate to stabilize the sacroiliac (SI) joints under different loads. They compared muscle activity in 30 men during two-legged and one-legged standing while holding we…
fasciasacroiliac jointload transferwire-spoke wheel modelarch theory; Self-bracing